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Developing networks of neural systems can exhibit spontaneous, synchronous activities called neural bursts, which can be important in the organization of functional neural circuits. Before the network matures, the activity level of a burst…

Neurons and Cognition · Quantitative Biology 2017-05-24 Chih-Hsu Huang , Yu-Ting Huang , Chun-Chung Chen , C. K. Chan

We report on the origin of synchronized bursting dynamics in various networks of neural spiking oscillators, when a certain threshold in coupling strength is exceeded. These ensembles synchronize at relatively low coupling strength and lose…

Chaotic Dynamics · Physics 2007-05-23 Mikhail V. Ivanchenko , Grigory V. Osipov , Vladimir D. Shalfeev , Jurgen Kurths

Spontaneous, synchronous bursting of neural population is a widely observed phenomenon in nervous networks, which is considered important for functions and dysfunctions of the brain. However, how the global synchrony across a large number…

Neurons and Cognition · Quantitative Biology 2022-06-08 Satohiro Tajima , Takeshi Mita , Douglas J. Bakkum , Hirokazu Takahashi , Taro Toyoizumi

All higher order central nervous systems exhibit spontaneous neural activity, though the purpose and mechanistic origin of such activity remains poorly understood. We explore the ignition and spread of collective spontaneous…

Neurons and Cognition · Quantitative Biology 2010-04-14 Michael I. Ham , Vadas Gintautas , Guenter W. Gross

We report experimental studies of synchronization phenomena in a pair of biological neurons that interact through naturally occurring, electrical coupling. When these neurons generate irregular bursts of spikes, the natural coupling…

Cultures of neurons grown on multi-electrode arrays have become a common experimental preparation for investigating developing neural networks. Experiment and simulation have shown that these developing networks eventually exhibit bursting…

Neurons and Cognition · Quantitative Biology 2026-02-27 Michael Stiber , Natalie Gonzales , Jewel YunHsuan Lee

At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis…

Neurons and Cognition · Quantitative Biology 2009-12-18 Hugo Gabriel Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

Adaptation to environmental change is a common property of biological systems. Cells initially respond to external changes in the environment, but after some time, they regain their original state. By considering an element consisting of…

Biological Physics · Physics 2015-05-13 Masayo Inoue , Kunihiko Kaneko

The onset of regular bursts in a group of irregularly bursting neurons with different individual properties is one of the most interesting dynamical properties found in neurobiological systems. In this paper we show how synchronization…

Chaotic Dynamics · Physics 2009-10-31 Nikolai F. Rulkov

A fundamental question in neuroscience is how structure and function of neural systems are related. We study this interplay by combining a familiar auto-associative neural network with an evolving mechanism for the birth and death of…

Adaptation and Self-Organizing Systems · Physics 2019-04-26 Ana P. Millán , J. J. Torres , S. Johnson , J. Marro

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Alexander Rothkegel , Christian E. Elger , Klaus Lehnertz

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa

Large networks of sparsely coupled, excitatory and inhibitory cells occur throughout the brain. A striking feature of these networks is that they are chaotic. How does this chaos manifest in the neural code? Specifically, how variable are…

Neurons and Cognition · Quantitative Biology 2014-02-25 Guillaume Lajoie , Jean-Philippe Thivierge , Eric Shea-Brown

This paper investigates the dependence of synchronization transitions of bursting oscillations on the information transmission delay over scale-free neuronal networks with attractive and repulsive coupling. It is shown that for both types…

Disordered Systems and Neural Networks · Physics 2011-01-10 Qingyun Wang , Guanrong Chen , Matjaz Perc

Multiple interlinked positive feedback loops shape the stimulus responses of various biochemical systems, such as the cell cycle or intracellular calcium release. Recent studies with simplified models have identified two advantages of…

Molecular Networks · Quantitative Biology 2012-08-31 Paul Smolen , Douglas A. Baxter , John H. Byrne

The analysis of the activity of neuronal cultures is considered to be a good proxy of the functional connectivity of in vivo neuronal tissues. Thus, the functional complex network inferred from activity patterns is a promising way to…

Neurons and Cognition · Quantitative Biology 2014-09-09 Sara Teller , Clara Granell , Manlio De Domenico , Jordi Soriano , Sergio Gomez , Alex Arenas

Research on synchronization of coupled oscillators has helped explain how uniform behavior emerges in populations of non-uniform systems. But explaining how uniform populations engage in sustainable non-uniform synchronization may prove to…

Chaotic Dynamics · Physics 2010-03-15 Adilson E. Motter

A network of propagating nonlinear oscillatory modes (waves) in the human brain is shown to generate collectively synchronized spiking activity (hypersynchronous spiking) when both amplitude and phase coupling between modes are taken into…

Biological Physics · Physics 2021-04-28 Vitaly L. Galinsky , Lawrence R. Frank

Genetic oscillators are present in the cells of many organisms and control several biological processes. The common feature of such oscillators is the presence of a protein which represses the transcription of its own gene. Recently, it has…

Molecular Networks · Quantitative Biology 2017-06-07 Nahuel Almeira , Sebastian Risau Gusman

In this paper, we investigated the neural spikes synchronisation in a neural network with synaptic plasticity and external perturbation. In the simulations the neural dynamics is described by the Hodgkin Huxley model considering chemical…

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