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Critically ill patients in regular wards are vulnerable to unanticipated adverse events which require prompt transfer to the intensive care unit (ICU). To allow for accurate prognosis of deteriorating patients, we develop a novel…

Machine Learning · Computer Science 2017-05-16 Ahmed M. Alaa , Scott Hu , Mihaela van der Schaar

Modeling continuous-time physiological processes that manifest a patient's evolving clinical states is a key step in approaching many problems in healthcare. In this paper, we develop the Hidden Absorbing Semi-Markov Model (HASMM): a…

Artificial Intelligence · Computer Science 2016-12-28 Ahmed M. Alaa , Mihaela van der Schaar

We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population…

Machine Learning · Computer Science 2016-05-04 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Objective: In this paper, we develop a personalized real-time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs; the proposed…

Artificial Intelligence · Computer Science 2016-10-28 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Detection of occult hemorrhage (i.e., internal bleeding) in patients in intensive care units (ICUs) can pose significant challenges for critical care workers. Because blood loss may not always be clinically apparent, clinicians rely on…

We report the development and validation of a data-driven real-time risk score that provides timely assessments for the clinical acuity of ward patients based on their temporal lab tests and vital signs, which allows for timely intensive…

Machine Learning · Computer Science 2017-05-23 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Accurately predicting the criticalness of ICU patients (such as in-ICU mortality risk) is vital for early intervention in critical care. However, conventional models often treat each patient in isolation and struggle to exploit the…

Machine Learning · Computer Science 2025-08-04 Mukesh Kumar Sahu , Pinki Roy

Machine learning (ML) applied to routine patient monitoring within intensive care units (ICUs) has the potential to improve care by providing clinicians with novel insights into each patient's health and expected response to interventions.…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Thomas Kite , Uzair Tahamid Siam , Brian Ayers , Nicholas Houstis , Aaron D Aguirre

We present a Discriminative Switching Linear Dynamical System (DSLDS) applied to patient monitoring in Intensive Care Units (ICUs). Our approach is based on identifying the state-of-health of a patient given their observed vital signs using…

Machine Learning · Computer Science 2015-04-27 Konstantinos Georgatzis , Christopher K. I. Williams

Cardiac biosignals, such as electrocardiograms (ECG) and photoplethysmograms (PPG), are of paramount importance for the diagnosis, prevention, and management of cardiovascular diseases, and have been extensively used in a variety of…

Computational models providing accurate estimates of their uncertainty are crucial for risk management associated with decision making in healthcare contexts. This is especially true since many state-of-the-art systems are trained using the…

Machine Learning · Computer Science 2022-06-09 Hongshu Liu , Nabeel Seedat , Julia Ive

Recently latent factor model (LFM) has been drawing much attention in recommender systems due to its good performance and scalability. However, existing LFMs predict missing values in a user-item rating matrix only based on the known ones,…

Machine Learning · Computer Science 2020-03-06 Chaochao Chen , Kevin C. Chang , Qibing Li , Xiaolin Zheng

Remote patient monitoring is crucial in modern healthcare, but current systems struggle with real-time analysis and prediction of vital signs. This paper presents a novel architecture combining deep learning with 5G network capabilities to…

Networking and Internet Architecture · Computer Science 2025-01-03 Iqra Batool

Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the…

Methodology · Statistics 2026-01-21 Xiaoru Huang , Tonghui Yu , Xiaoyu Liu

Survival time prediction from medical images is important for treatment planning, where accurate estimations can improve healthcare quality. One issue affecting the training of survival models is censored data. Most of the current survival…

Computer Vision and Pattern Recognition · Computer Science 2022-05-27 Renato Hermoza , Gabriel Maicas , Jacinto C. Nascimento , Gustavo Carneiro

In Intensive Care Units (ICU), the abundance of multivariate time series presents an opportunity for machine learning (ML) to enhance patient phenotyping. In contrast to previous research focused on electronic health records (EHR), here we…

Machine Learning · Computer Science 2024-10-04 Hollan Haule , Ian Piper , Patricia Jones , Tsz-Yan Milly Lo , Javier Escudero

Continuous glucose monitoring (CGM) combined with AI offers new opportunities for proactive diabetes management through real-time glucose forecasting. However, most existing models are task-specific and lack generalization across patient…

Quantitative Methods · Quantitative Biology 2025-08-04 Junjie Luo , Abhimanyu Kumbara , Mansur Shomali , Rui Han , Anand Iyer , Ritu Agarwal , Gordon Gao

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal,…

Machine Learning · Computer Science 2025-10-28 Yujie Xiao , Gongzhen Tang , Wenhui Liu , Jun Li , Guangkun Nie , Zhuoran Kan , Deyun Zhang , Qinghao Zhao , Shenda Hong

This paper presents a new and flexible prognostics framework based on a higher order hidden semi-Markov model (HOHSMM) for systems or components with unobservable health states and complex transition dynamics. The HOHSMM extends the basic…

Applications · Statistics 2020-02-14 Ying Liao , Yisha Xiang , Min Wang

Recent work on predicting patient outcomes in the Intensive Care Unit (ICU) has focused heavily on the physiological time series data, largely ignoring sparse data such as diagnoses and medications. When they are included, they are usually…

Machine Learning · Computer Science 2021-01-12 Emma Rocheteau , Catherine Tong , Petar Veličković , Nicholas Lane , Pietro Liò
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