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Increasing emphasis on data and quantitative methods in the biomedical sciences is making biological research more computational. Collecting, curating, processing, and analysing large genomic and imaging data sets poses major computational…

Quantitative Methods · Quantitative Biology 2021-09-22 Elisabeth Roesch , Joe G. Greener , Adam L. MacLean , Huda Nassar , Christopher Rackauckas , Timothy E. Holy , Michael P. H. Stumpf

We present an open source computational framework geared towards the efficient numerical investigation of open quantum systems written in the Julia programming language. Built exclusively in Julia and based on standard quantum optics…

Quantum Physics · Physics 2018-03-14 Sebastian Krämer , David Plankensteiner , Laurin Ostermann , Helmut Ritsch

Apart from forming the backbone of compiler optimization, static dataflow analysis has been widely applied in a vast variety of applications, such as bug detection, privacy analysis, program comprehension, etc. Despite its importance,…

Programming Languages · Computer Science 2024-12-18 Zewen Sun , Yujin Zhang , Duanchen Xu , Yiyu Zhang , Yun Qi , Yueyang Wang , Yi Li , Zhaokang Wang , Yue Li , Xuandong Li , Zhiqiang Zuo , Qingda Lu , Wenwen Peng , Shengjian Guo

Constraint-based metabolic modeling is the predominant framework for simulating cellular metabolism. The central assumption of these models is that metabolism operates at a steady state, meaning that the production and consumption rates of…

Quantitative Methods · Quantitative Biology 2026-05-22 Ariel Bruner , Mona Singh

Reinforcement Learning (RL) has proven highly effective in addressing complex control and decision-making tasks. However, in most traditional RL algorithms, the policy is typically parameterized as a diagonal Gaussian distribution, which…

Machine Learning · Computer Science 2026-04-02 Ruijie Hao , Longfei Zhang , Yang Dai , Yang Ma , Xingxing Liang , Guangquan Cheng

Distributed resource allocation (DRA) is fundamental to modern networked systems, spanning applications from economic dispatch in smart grids to CPU scheduling in data centers. Conventional DRA approaches require reliable communication, yet…

Systems and Control · Electrical Eng. & Systems 2025-10-22 Mohammadreza Doostmohammadian , Sergio Pequito

Detailed chemistry-based computational fluid dynamics (CFD) simulations are computationally expensive due to the solution of the underlying chemical kinetics system of ordinary differential equations (ODEs). Here, we introduce a novel…

Split Federated Learning (SFL) is a distributed machine learning framework which strategically divides the learning process between a server and clients and collaboratively trains a shared model by aggregating local models updated based on…

Machine Learning · Computer Science 2025-12-29 Jiarong Yang , Yuan Liu

Distributed diffusion is a powerful algorithm for multi-task state estimation which enables networked agents to interact with neighbors to process input data and diffuse information across the network. Compared to a centralized approach,…

Multiagent Systems · Computer Science 2020-03-27 Jiani Li , Xenofon Koutsoukos

We present Groebner.jl, a Julia package for computing Groebner bases with the F4 algorithm. Groebner.jl is an efficient, portable, and open-source software. Groebner.jl works over integers modulo a prime and over the rationals, supports…

Mathematical Software · Computer Science 2024-02-13 Alexander Demin , Shashi Gowda

Federated Learning (FL) enables collaborative model training across multiple clients while preserving data privacy. Traditional FL methods often use a global model to fit all clients, assuming that clients' data are independent and…

Machine Learning · Computer Science 2025-12-01 Dario Fenoglio , Mohan Li , Pietro Barbiero , Nicholas D. Lane , Marc Langheinrich , Martin Gjoreski

This paper presents a distributed simulation based method for harmonic resonance assessment (HRA) in multi-area large-scale power systems. Further consideration is devoted to the early harmonic frequency-scan formulation to shape them into…

Signal Processing · Electrical Eng. & Systems 2018-08-22 Amirreza Sahami , Shahram Montaser Kouhsari

We present FreeBird, an extensible Julia-based platform for computational studies of phase equilibria at generic interfaces. The package supports a range of system configurations, from atomistic solid surfaces to coarse-grained…

Statistical Mechanics · Physics 2025-12-19 Ray Yang , Junchi Chen , Douglas Thibodeaux , Robert B. Wexler

Quite generally, constraint-based metabolic flux analysis describes the space of viable flux configurations for a metabolic network as a high-dimensional polytope defined by the linear constraints that enforce the balancing of production…

Molecular Networks · Quantitative Biology 2013-09-24 Francesco Alessandro Massucci , Francesc Font-Clos , Andrea De Martino , Isaac Pérez Castillo

As astronomical data grows in volume and complexity, the scalability of analysis software becomes increasingly important. At the same time, astrophysics analysis software relies heavily on open-source contributions, so languages and tools…

Instrumentation and Methods for Astrophysics · Physics 2024-02-01 Edward Berman , Jacqueline McCleary

Cybersecurity threats highlight the need for robust network intrusion detection systems to identify malicious behaviour. These systems rely heavily on large datasets to train machine learning models capable of detecting patterns and…

Cryptography and Security · Computer Science 2025-01-14 Daniela Pinto , Ivone Amorim , Eva Maia , Isabel Praça

Flux analysis is a class of constraint-based approaches to the study of biochemical reaction networks: they are based on determining the reaction flux configurations compatible with given stoichiometric and thermodynamic constraints. One of…

Molecular Networks · Quantitative Biology 2015-05-18 A. De Martino , E. Marinari

Accurate and efficient methods to simulate nonadiabatic and quantum nuclear effects in high-dimensional and dissipative systems are crucial for the prediction of chemical dynamics in condensed phase. To facilitate effective development,…

Constraint based methods, such as the Flux Balance Analysis, are widely used to model cellular growth processes without relying on extensive information on the regulatory features. The regulation is instead substituted by an optimization…

Optimization and Control · Mathematics 2017-06-14 Henning Lindhorst , Sergio Lucia , Rolf Findeisen , Steffen Waldherr

Computational load imbalance is a well-known performance issue in multiprocessor reacting flow simulations utilizing directly integrated chemical kinetics. We introduce an open-source dynamic load balancing model named DLBFoam to address…

Fluid Dynamics · Physics 2021-06-29 Bulut Tekgül , Petteri Peltonen , Heikki Kahila , Ossi Kaario , Ville Vuorinen