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Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Yejia Zhang , Xinrong Hu , Nishchal Sapkota , Yiyu Shi , Danny Z. Chen

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

A widely used approach for extracting information from gene expression data employ the construction of a gene co-expression network and the subsequent application of algorithms that discover network structure. In particular, a common goal…

Genomics · Quantitative Biology 2024-08-20 Niloofar Aghaieabiane , Ioannis Koutis

Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those methods aim to streamline the analysis of scRNA-seq data by focusing on the most informative…

Artificial Intelligence · Computer Science 2024-06-12 Weiliang Zhang , Zhen Meng , Dongjie Wang , Min Wu , Kunpeng Liu , Yuanchun Zhou , Meng Xiao

Characterizing patient somatic mutations through next-generation sequencing technologies opens up possibilities for refining cancer subtypes. However, catalogues of mutations reveal that only a small fraction of the genes are altered…

Computational Engineering, Finance, and Science · Computer Science 2017-01-05 Ali Burak Ünal , Öznur Taştan

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

Gene annotation addresses the problem of predicting unknown associations between gene and functions (e.g., biological processes) of a specific organism. Despite recent advances, the cost and time demanded by annotation procedures that rely…

Machine Learning · Computer Science 2022-05-02 Miguel Romero , Oscar Ramírez , Jorge Finke , Camilo Rocha

The methodology of community detection can be divided into two principles: imposing a network model on a given graph, or optimizing a designed objective function. The former provides guarantees on theoretical detectability but falls short…

Machine Learning · Statistics 2017-10-06 Pin-Yu Chen , Lingfei Wu

Spatial variable genes (SVGs) reveal critical information about tissue architecture, cellular interactions, and disease microenvironments. As spatial transcriptomics (ST) technologies proliferate, accurately identifying SVGs across diverse…

Applications · Statistics 2025-10-21 Jiawen Chen , Jinwei Zhang , Dongshen Peng , Yutong Song , Aitong Ruan , Yun Li , Didong Li

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Unsupervised region representation learning aims to extract dense and effective features from unlabeled urban data. While some efforts have been made for solving this problem based on multiple views, existing methods are still insufficient…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Liang Zhang , Cheng Long , Gao Cong

To understand the nature of a cell, one needs to understand the structure of its genome. For this purpose, experimental techniques such as Hi-C detecting chromosomal contacts are used to probe the three-dimensional genomic structure. These…

Quantitative Methods · Quantitative Biology 2019-09-23 Andreas Hofmann , Fatema Zahra Rashid , Frédéric Crémazy , Remus T. Dame , Dieter W. Heermann

Semi-supervised learning has substantially advanced medical image segmentation since it alleviates the heavy burden of acquiring the costly expert-examined annotations. Especially, the consistency-based approaches have attracted more…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Zhe Xu , Yixin Wang , Donghuan Lu , Lequan Yu , Jiangpeng Yan , Jie Luo , Kai Ma , Yefeng Zheng , Raymond Kai-yu Tong

Deep convolutional neural networks (CNNs) have shown excellent performance in object recognition tasks and dense classification problems such as semantic segmentation. However, training deep neural networks on large and sparse datasets is…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Lorenz Berger , Eoin Hyde , M. Jorge Cardoso , Sebastien Ourselin

Multi-label image classification presents a challenging task in many domains, including computer vision and medical imaging. Recent advancements have introduced graph-based and transformer-based methods to improve performance and capture…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Ahmad Sajedi , Samir Khaki , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Saban Ozturk , Tolga Cukur

The ability to accurately detect and classify objects at varying pixel sizes in cluttered scenes is crucial to many Navy applications. However, detection performance of existing state-of the-art approaches such as convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2017-08-28 JT Turner , Kalyan Moy Gupta , David Aha

We introduce a novel method to analyse complete genomes and recognise some distinctive features by means of an adaptive compression algorithm, which is not DNA-oriented. We study the Information Content as a function of the number of…

Genomics · Quantitative Biology 2007-05-23 Giulia Menconi

Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased genomes have already been sequenced; however, obtaining the…

Genomics · Quantitative Biology 2024-06-18 Teddy Lazebnik , Liron Simon-Keren

Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can…

Subcellular Processes · Quantitative Biology 2019-06-19 Jingyu Zhang , Hengyu Chen , Ruoyan Li , David A. Taft , Guang Yao , Fan Bai , Jianhua Xing