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Over the last two decades, the field of computational science has seen a dramatic shift towards incorporating high-throughput computation and big-data analysis as fundamental pillars of the scientific discovery process. This has…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-18 Martin Uhrin , Sebastiaan P. Huber , Jusong Yu , Nicola Marzari , Giovanni Pizzi

The advent of data-driven science in the 21st century brought about the need for well-organized structured data and associated infrastructure able to facilitate the applications of Artificial Intelligence and Machine Learning. We present an…

Databases · Computer Science 2022-03-03 Alexander Zech , Timur Bazhirov

While machine learning has emerged in recent years as a useful tool for rapid prediction of materials properties, generating sufficient data to reliably train models without overfitting is still impractical for many applications. Towards…

Materials Science · Physics 2022-07-29 Rees Chang , Yu-Xiong Wang , Elif Ertekin

The recent advancements in multicore machines highlight the need to simplify concurrent programming in order to leverage their computational power. One way to achieve this is by designing efficient concurrent data structures (e.g. stacks,…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-31 Nikolaos D. Kallimanis

Scientific progress increasingly depends on synthesizing knowledge across vast literature, yet most experimental data remains trapped in semi-structured formats that resist systematic extraction and analysis. Here, we present MatSKRAFT, a…

Information Retrieval · Computer Science 2025-09-15 Kausik Hira , Mohd Zaki , Mausam , N. M. Anoop Krishnan

Scientific communities naturally tend to organize around data ecosystems created by the combination of their observational devices, their data repositories, and the workflows essential to carry their research from observation to discovery.…

Networking and Internet Architecture · Computer Science 2021-06-30 Mark Asch , François Bodin , Micah Beck , Terry Moore , Michela Taufer , Martin Swany , Jean-Pierre Vilotte

Recently, computational modeling has shifted towards the use of deep learning, and other data-driven modeling frameworks. Although this shift in modeling holds promise in many applications like design optimization and real-time control by…

Fluid Dynamics · Physics 2021-10-11 Suraj Pawar , Omer San , Prakash Vedula , Adil Rasheed , Trond Kvamsdal

The automation of scientific discovery represents a critical milestone in Artificial Intelligence (AI) research. However, existing agentic systems for science suffer from two fundamental limitations: rigid, pre-programmed workflows that…

Artificial Intelligence · Computer Science 2025-10-20 Ed Li , Junyu Ren , Xintian Pan , Cat Yan , Chuanhao Li , Dirk Bergemann , Zhuoran Yang

As Large Language Models (LLMs) become ubiquitous across various scientific domains, their lack of ability to perform complex tasks like running simulations or to make complex decisions limits their utility. LLM-based agents bridge this gap…

Computation and Language · Computer Science 2026-01-21 Anurag Acharya , Timothy Vega , Rizwan A. Ashraf , Anshu Sharma , Derek Parker , Robert Rallo

The growing reliance on data-driven applications in sectors such as healthcare, finance, and law enforcement underscores the need for secure, privacy-preserving, and scalable mechanisms for data generation and sharing. Synthetic data…

Cryptography and Security · Computer Science 2025-08-21 Eduardo Brito , Mahmoud Shoush , Kristian Tamm , Paula Etti , Liina Kamm

To harness the potential of advanced computing technologies, efficient (real time) analysis of large amounts of data is as essential as are front-line simulations. In order to optimise this process, experts need to be supported by…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-03 Jovana Knežević , Ralf-Peter Mundani , Ernst Rank

The current landscape of AI for Science (AI4S) is predominantly anchored in large-scale textual corpora, where generative AI systems excel at hypothesis generation, literature search, and multi-modal reasoning. However, a critical…

The emergence of "big data" offers unprecedented opportunities for not only accelerating scientific advances but also enabling new modes of discovery. Scientific progress in many disciplines is increasingly enabled by our ability to examine…

Computers and Society · Computer Science 2017-07-03 Vasant G. Honavar , Mark D. Hill , Katherine Yelick

Design, control, and estimation for dynamic systems require accurate and analytically tractable models. However, modern engineered systems contain components that are described with heterogeneous modeling paradigms, as well as subsystems…

Systems and Control · Electrical Eng. & Systems 2026-04-21 Leeroy Makusha , Preston Abadie , Donald J. Docimo

Engineering efficient implementations of compact and succinct structures is a time-consuming and challenging task, since there is no standard library of easy-to- use, highly optimized, and composable components. One consequence is that…

Data Structures and Algorithms · Computer Science 2013-11-07 Simon Gog , Timo Beller , Alistair Moffat , Matthias Petri

Large language models (LLMs) have shown impressive performance on general-purpose tasks, yet adapting them to specific domains remains challenging due to the scarcity of high-quality domain data. Existing data synthesis tools often struggle…

Computation and Language · Computer Science 2025-07-08 Ziyang Miao , Qiyu Sun , Jingyuan Wang , Yuchen Gong , Yaowei Zheng , Shiqi Li , Richong Zhang

The increasingly collaborative, globalized nature of scientific research combined with the need to share data and the explosion in data volumes present an urgent need for a scientific data management system (SDMS). An SDMS presents a…

Databases · Computer Science 2020-04-09 Dale Stansberry , Suhas Somnath , Jessica Breet , Gregory Shutt , Mallikarjun Shankar

High Performance Computing (HPC) centers provide advanced infrastructure that enables scientific research at extreme scale. These centers operate with hardware configurations, software environments, and security requirements that differ…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-03 Sean R. Wilkinson , Patrick Widener , Sarp Oral , Rafael Ferreira da Silva

Autonomous materials research systems allow scientists to fail smarter, learn faster, and spend less resources in their studies. As these systems grow in number, capability, and complexity, a new challenge arises - how will they work…

Multiagent Systems · Computer Science 2023-03-21 A. Gilad Kusne , Austin McDannald

The collaborative efforts of large communities in science experiments, often comprising thousands of global members, reflect a monumental commitment to exploration and discovery. Recently, advanced and complex data processing has gained…