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Developing automated and semi-automated solutions for reconstructing wiring diagrams of the brain from electron micrographs is important for advancing the field of connectomics. While the ultimate goal is to generate a graph of neuron…

Computer Vision and Pattern Recognition · Computer Science 2016-08-09 William Gray Roncal , Colin Lea , Akira Baruah , Gregory D. Hager

Recent characterisations of self-organising systems depend upon the presence of a Markov blanket: a statistical boundary that mediates the interactions between what is inside of and outside of a system. We leverage this idea to provide an…

Neurons and Cognition · Quantitative Biology 2020-06-05 Ines Hipolito , Maxwell Ramstead , Laura Convertino , Anjali Bhat , Karl Friston , Thomas Parr

Neuroscience has long informed the development of artificial neural networks, but the success of modern architectures invites, in turn, the converse: can modern networks teach us lessons about brain function? Here, we examine the structure…

Neurons and Cognition · Quantitative Biology 2026-03-17 Peter Koenig , Mario Negrello

Networks have become the de facto diagram of the Big Data age (try searching Google Images for [big data AND visualisation] and see). The concept of networks has become central to many fields of human inquiry and is said to revolutionise…

Social and Information Networks · Computer Science 2018-06-22 Liliana Bounegru , Tommaso Venturini , Jonathan Gray , Mathieu Jacomy

The power of any kind of network approach lies in the ability to simplify a complex system so that one can better understand its function as a whole. Sometimes it is beneficial, however, to include more information than in a simple graph of…

Physics and Society · Physics 2015-09-21 Petter Holme

Technological advancements in noninvasive imaging facilitate the construction of whole brain interconnected networks, known as brain connectivity. Existing approaches to analyze brain connectivity frequently disaggregate the entire network…

Methodology · Statistics 2023-09-26 Xinyuan Tian , Fan Li , Li Shen , Denise Esserman , Yize Zhao

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Individual differences in human intelligence can be modeled and predicted from in vivo neurobiological connectivity. Many established modeling frameworks for predicting intelligence, however, discard higher-order information about…

Neurons and Cognition · Quantitative Biology 2022-03-07 Evan D. Anderson , Ramsey Wilcox , Anuj Nayak , Christopher Zwilling , Pablo Robles-Granda , Been Kim , Lav R. Varshney , Aron K. Barbey

From interacting cellular components to networks of neurons and neural systems, interconnected units comprise a fundamental organizing principle of the nervous system. Understanding how their patterns of connections and interactions give…

Neurons and Cognition · Quantitative Biology 2018-08-01 Danielle S. Bassett , Perry Zurn , Joshua I. Gold

Studying neural connectivity is considered one of the most promising and challenging areas of modern neuroscience. The underpinnings of cognition are hidden in the way neurons interact with each other. However, our experimental methods of…

Machine Learning · Statistics 2018-06-22 George Panagopoulos

Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…

Social and Information Networks · Computer Science 2020-06-11 Tommaso Lanciano , Francesco Bonchi , Aristides Gionis

Neuroscience is undergoing faster changes than ever before. Over 100 years our field qualitatively described and invasively manipulated single or few organisms to gain anatomical, physiological, and pharmacological insights. In the last 10…

Neurons and Cognition · Quantitative Biology 2016-08-12 Danilo Bzdok , B. T. Thomas Yeo

Brain connectivity analysis is crucial for understanding brain structure and neurological function, shedding light on the mechanisms of mental illness. To study the association between individual brain connectivity networks and the clinical…

Whole-brain network analyses remain the vanguard in neuroimaging research, coming to prominence within the last decade. Network science approaches have facilitated these analyses and allowed examining the brain as an integrated system.…

Applications · Statistics 2015-05-04 Sean L. Simpson , Paul J. Laurienti

To further advance our understanding of the brain, new concepts and theories are needed. In particular, the ability of the brain to create information flows must be reconciled with its propensity for synchronization and mass action. The…

Neurons and Cognition · Quantitative Biology 2014-07-04 Emmanuelle Tognoli , J. A. Scott Kelso

The networking field has recently started to incorporate artificial intelligence (AI), machine learning (ML), big data analytics combined with advances in networking (such as software-defined networks, network functions virtualization, and…

Computers and Society · Computer Science 2018-04-10 Touseef Yaqoob , Muhammad Usama , Junaid Qadir , Gareth Tyson

Tremendous neuroscientific progress has recently been made by mapping brain connectivity, complementing extensive knowledge of task-evoked brain activation patterns. However, despite evidence that they are related, these connectivity and…

Neurons and Cognition · Quantitative Biology 2024-02-06 Michael W. Cole

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

Neurons and Cognition · Quantitative Biology 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Many recent efforts in computational modeling of macro-scale brain dynamics have begun to take a data-driven approach by incorporating structural and/or functional information derived from subject data. Here, we discuss recent work using…

Neurons and Cognition · Quantitative Biology 2018-11-15 Kanika Bansal , Johan Nakuci , Sarah Feldt Muldoon

With the increasing availability and size of multi-omics datasets, investigating the casual relationships between molecular phenotypes has become an important aspect of exploring underlying biology and genetics. This paper aims to introduce…

Molecular Networks · Quantitative Biology 2022-01-31 Jack Kelly , Carlo Berzuini , Bernard Keavney , Maciej Tomaszewski , Hui Guo