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Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space…

Populations and Evolution · Quantitative Biology 2014-12-18 Chiara Poletto , Sandro Meloni , Ashleigh Van Metre , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergence, maintenance, and evolution. The full description of…

Populations and Evolution · Quantitative Biology 2013-08-21 Chiara Poletto , Sandro Meloni , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Host mobility plays a fundamental role in the spatial spread of infectious diseases. Previous theoretical works based on the integration of network theory into the metapopulation framework have shown that the heterogeneities that…

Physics and Society · Physics 2013-09-26 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

We formulate a compartmental model for the propagation of a respiratory disease in a patchy environment. The patches are connected through the mobility of individuals, and we assume that disease transmission and recovery are possible during…

Populations and Evolution · Quantitative Biology 2021-10-11 Indrajit Ghosh , Sk Shahid Nadim , Soumyendu Raha , Debnath Pal

The structure of heterogeneous networks and human mobility patterns profoundly influence the spreading of endemic diseases. In small-scale communities, individuals engage in social interactions within confined environments, such as homes…

Physics and Society · Physics 2025-05-20 Yusheng Li , Yichao Yao , Minyu Feng , Tina P. Benko , Matjaž Perc , Jernej Završnik

Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements,…

Physics and Society · Physics 2021-07-26 Wesley Cota , David Soriano-Paños , Alex Arenas , Silvio C. Ferreira , Jesús Gómez-Gardeñes

The spatial structure of populations is a key element in the understanding of the large scale spreading of epidemics. Motivated by the recent empirical evidence on the heterogeneous properties of transportation and commuting patterns among…

Populations and Evolution · Quantitative Biology 2008-03-19 Vittoria Colizza , Alessandro Vespignani

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

The spread of infectious disease and the evolution of antigenically distinct strains are often modeled separately, despite strong feedbacks mediated by host immune memory and heterogeneous contacts. To tackle this challenging problem, we…

Populations and Evolution · Quantitative Biology 2026-04-01 Davide Zanchetta , Vittoria Bettio , Sandro Azaele , Manlio De Domenico

Mathematical disease modelling has long operated under the assumption that any one infectious disease is caused by one transmissible pathogen spreading among a population. This paradigm has been useful in simplifying the biological reality…

Populations and Evolution · Quantitative Biology 2021-06-02 Blake J. M. Williams , Guillaume St-Onge , Laurent Hébert-Dufresne

We use a stochastic metapopulation model to study the combined effects of seasonality and spatial heterogeneity on disease persistence. We find a pronounced effect of enhanced persistence associated with strong heterogeneity, intermediate…

Populations and Evolution · Quantitative Biology 2015-02-23 Ganna Rozhnova , Ana Nunes , Alan J. McKane

Epidemic spreading over populations networks has been an important subject of research for several decades, and especially during the Covid-19 pandemic. Most epidemic outbreaks are likely to create multiple mutations during their spreading…

Populations and Evolution · Quantitative Biology 2025-09-30 Aviel Ivry , Reuven Cohen , Amikam Patron

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

The analysis of contagion-diffusion processes in metapopulations is a powerful theoretical tool to study how mobility influences the spread of communicable diseases. Nevertheless, many metapopulation approaches use indistinguishable agents…

Physics and Society · Physics 2022-04-20 Pablo Valgañón , David Soriano-Paños , Alex Arenas , Jesús Gómez-Gardeñes

Despite the advanced stage of epidemic modeling, there is a major demand for methods to incorporate behavioral responses to the spread of a disease such as social distancing and adoption of prevention methods. Mobility plays an important…

Physics and Society · Physics 2022-03-14 Paulo Cesar Ventura , Alberto Aleta , Francisco A. Rodrigues , Yamir Moreno

Human mobility and activity patterns mediate contagion on many levels, including the spatial spread of infectious diseases, diffusion of rumors, and emergence of consensus. These patterns however are often dominated by specific locations…

Physics and Society · Physics 2011-07-05 Duygu Balcan , Alessandro Vespignani

The dynamics of epidemic spreading is often reduced to the single control parameter $R_0$, whose value, above or below unity, determines the state of the contagion. If, however, the pathogen evolves as it spreads, $R_0$ may change over…

Populations and Evolution · Quantitative Biology 2022-11-07 Xiyun Zhang , Zhongyuan Ruan , Muhua Zheng , Jie Zhou , Stefano Boccaletti , Baruch Barzel

We present a thorough inspection of the dynamical behavior of epidemic phenomena in populations with complex and heterogeneous connectivity patterns. We show that the growth of the epidemic prevalence is virtually instantaneous in all…

Disordered Systems and Neural Networks · Physics 2007-05-23 Marc Barthelemy , Alain Barrat , Romualdo Pastor-Satorras , Alessandro Vespignani
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