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Controlling an epidemiological model is often performed using optimal control theory techniques for which the solution depends on the equations of the control system, objective functional and possible state and/or control constraints. In…

Optimization and Control · Mathematics 2021-11-25 Loïc Michel , Cristiana J. Silva , Delfim F. M. Torres

Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment…

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

Optimization and Control · Mathematics 2021-02-16 Aaron Z. Palmer , Zelda B. Zabinsky , Shan Liu

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

Populations and Evolution · Quantitative Biology 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

We propose a model predictive control (MPC) approach for minimising the social distancing and quarantine measures during a pandemic while maintaining a hard infection cap. To this end, we study the admissible and the maximal robust…

Optimization and Control · Mathematics 2022-05-05 Philipp Sauerteig , Willem Esterhuizen , Mitsuru Wilson , Tobias K. S. Ritschel , Karl Worthmann , Stefan Streif

A model with six mutually-exclusive compartments related to dengue is studied. Three vector control tools are considered: insecticides (larvicide and adulticide) and mechanical control. The basic reproduction number associated to the model…

Optimization and Control · Mathematics 2013-11-26 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

We present an application of optimal control theory to Dengue epidemics. This epidemiologic disease is an important theme in tropical countries due to the growing number of infected individuals. The dynamic model is described by a set of…

Optimization and Control · Mathematics 2010-08-27 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

We analyze the optimal control of disease prevention and treatment in a basic SIS model. We develop a simple macroeconomic setup in which the social planner determines how to optimally intervene, through income taxation, in order to…

Theoretical Economics · Economics 2019-10-09 Davide La Torre , Tufail Malik , Simone Marsiglio

In this work, two mathematical models for malaria under resistance are presented. More precisely, the first model shows the interaction between humans and mosquitoes inside a patch under infection of malaria when the human population is…

Populations and Evolution · Quantitative Biology 2020-02-04 Cristhian Montoya , Jhoana P. Romero-Leiton

Despite extensive control efforts over the centuries, cholera remains a globally significant health issue. Seasonal emergence of cholera cases has been reported, particularly in the Bengal delta region, which is often synchronized with…

Populations and Evolution · Quantitative Biology 2025-03-31 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Jon Pitchford , Joydev Chattopadhyay

We propose a tractable epidemic model that includes containment measures. In the absence of containment measures, the epidemics spread exponentially fast whenever the infectivity rate is positive, $\lambda>0$. The containment measures are…

Populations and Evolution · Quantitative Biology 2020-10-29 Ginestra Bianconi , Pavel L. Krapivsky

We develop a mathematical model, based on a system of ordinary differential equations, to the upshot of farming alertness in crop pest administration, bearing in mind plant biomass, pest, and level of control. Main qualitative analysis of…

Optimization and Control · Mathematics 2021-06-21 Teklebirhan Abraha , Fahad Al Basir , Legesse Lemecha Obsu , Delfim F. M. Torres

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

Populations and Evolution · Quantitative Biology 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin

We consider a behavioral-feedback SIR epidemic model, in which the infection rate depends in feedback on the fractions of susceptible and infected agents, respectively. The considered model allows one to account for endogenous adaptation…

Systems and Control · Electrical Eng. & Systems 2026-02-11 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We propose and analyse an optimal control problem where the control system is a mathematical model for tuberculosis that considers reinfection. The control functions represent the fraction of early latent and persistent latent individuals…

Optimization and Control · Mathematics 2014-10-13 Paula Rodrigues , Cristiana J. Silva , Delfim F. M. Torres

A deterministic mathematical model is formulated and analyzed to study the transmission dynamics of Nipah virus both qualitatively and numerically. Existence and stability of equilibria were investigated and the model was rigorously…

Dynamical Systems · Mathematics 2020-10-09 BI Omede , PO Ameh , A Omame , B Bolaji

The COVID-19 pandemic has forced policy makers to decree urgent confinements to stop a rapid and massive contagion. However, after that stage, societies are being forced to find an equilibrium between the need to reduce contagion rates and…

We study the effects of switching social contacts as a strategy to control epidemic outbreaks. Connections between susceptible and infective individuals can be broken by either individual, and then reconnected to a randomly chosen member of…

Populations and Evolution · Quantitative Biology 2008-06-12 Sebastian Risau-Gusman , Damian H. Zanette

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

Optimal control of interdependent epidemics spreading over complex networks is a critical issue. We first establish a framework to capture the coupling between two epidemics, and then analyze the system's equilibrium states by categorizing…

Systems and Control · Computer Science 2017-10-19 Juntao Chen , Rui Zhang , Quanyan Zhu
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