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Microplastics (MPs) are ubiquitous in all ecosystems, affecting wildlife and, ultimately, human health. The complexity of natural samples plus the unspecificity of their treatments to isolate polymers renders the characterization of…

Instrumentation and Detectors · Physics 2025-04-01 Adrian Lopez-Rosales , Jose Andrade , Borja Ferreiro , Soledad Muniategui

We have developed a global analysis model for randomly oriented, fully hydrated inverted hexagonal (H$_\text{II}$) phases formed by many amphiphiles in aqueous solution, including membrane lipids. The model is based on a structure factor…

Biomolecules · Quantitative Biology 2019-04-08 Moritz P. K. Frewein , Michael Rumetshofer , Georg Pabst

Physical models of biological systems can become difficult to interpret when they have a large number of parameters. But the models themselves actually depend on (i.e. are sensitive to) only a subset of those parameters. Rigorously…

Biological Physics · Physics 2018-11-27 Chieh-Ting Hsu , Gary J. Brouhard , Paul François

We investigate protein-protein interactions in solution by small-angle X-ray scattering (SAXS) and theoretical modeling. The structure factor for solutions of bovine pancreatic trypsin inhibitor (BPTI), myoglobin (Mb), and intestinal fatty…

Biological Physics · Physics 2014-08-29 Shuji Kaieda , Mikael Lund , Tomás S. Plivelic , Bertil Halle

Laser-induced breakdown spectroscopy (LIBS) is a laser based diagnostics used to study atomic emission from the expanding plasma plume formed during the laser-matter interaction. It provides valuable information about the composition of the…

Optics · Physics 2014-07-03 V. N. Rai , Awadhesh K. Rai , Fang-Yu Yueh , J. P. Singh

Multiple types or views of data (e.g. genetics, proteomics) measured on the same set of individuals are now popularly generated in many biomedical studies. A particular interest might be the detection of sample subgroups (e.g. subtypes of…

Methodology · Statistics 2025-05-09 Kaifeng Yang , Thierry Chekouo , Sandra E. Safo

Single-cell proteomics (SCP) is transforming our understanding of biological complexity by shifting from bulk proteomics, where signals are averaged over thousands of cells, to the proteome analysis of individual cells. This granular…

Quantitative Methods · Quantitative Biology 2025-04-01 Amanda Momenzadeh , Jesse G. Meyer

Biomolecular condensates composed of intrinsically disordered proteins (IDPs) are vital for proper cellular function, and their dysfunction is associated with diseases including neurodegeneration and cancer. Despite their biological…

Soft Condensed Matter · Physics 2025-02-21 Luke K. Davis , Andrew J. Baldwin , Philip Pearce

The survival of time-reversal symmetry in the presence of strong multiple scattering lies at the heart of some of the most robust interference effects of light in complex media. Here, the use of time-reversed light paths for imaging in…

Optics · Physics 2020-04-22 Jesse Dykes , Zeina Nazer , Allard P. Mosk , Otto L. Muskens

Small-x DIS is described as the scattering of a partonic fluctuation of the photon off a superposition of target color fields. Diffraction occurs if the emerging partonic state is in a color singlet. Introducing a specific model for the…

High Energy Physics - Phenomenology · Physics 2010-03-25 W. Buchmuller , T. Gehrmann , A. Hebecker

The protein-protein interactions (PPIs) are crucial for understanding the majority of cellular processes. PPIs play important role in gene transcription regulation, cellular signaling, molecular basis of immune response and more. Moreover,…

Biomolecules · Quantitative Biology 2016-05-31 Maciej Pawel Ciemny , Mateusz Kurcinski , Andrzej Kolinski , Sebastian Kmiecik

Protein structure reconstruction from Nuclear Magnetic Resonance (NMR) experiments largely relies on computational algorithms. Recently, some effective low-rank matrix completion (MC) methods, such as ASD and ScaledASD, have been…

Biological Physics · Physics 2018-09-24 Z. Li , S. Li , X. Wei , X. Peng , Q. Zhao

This work aims to build connections between the electromagnetic and communication aspects of Reconfigurable Intelligent Surfaces (RIS) by proposing a methodology to combine outputs from electromagnetic RIS design into an RIS-tailored…

Applied Physics · Physics 2025-01-03 Sravan K. R. Vuyyuru , Le Hao , Markus Rupp , Sergei A. Tretyakov , Risto Valkonen

The ability to characterize proteins at sequence-level resolution is vital to biological research. Currently, the leading method for protein sequencing is by liquid chromatography mass spectrometry (LC-MS) whereas proteins are reduced to…

Genomics · Quantitative Biology 2025-07-11 René L. Warren

Understanding protein dynamics are essential for deciphering protein functional mechanisms and developing molecular therapies. However, the complex high-dimensional dynamics and interatomic interactions of biological processes pose…

Quantitative Methods · Quantitative Biology 2025-05-15 Tiexin Qin , Mengxu Zhu , Chunyang Li , Terry Lyons , Hong Yan , Haoliang Li

Disordered dielectrics with structural correlations on length scales comparable to visible light wavelengths exhibit complex optical properties. Such materials exist in nature, leading to beautiful structural non-iridescent color, and they…

Optics · Physics 2022-02-02 Pavel Yazhgur , Geoffroy J. Aubry , Luis S. Froufe , Frank Scheffold

The sol-gel silica glasses doped with copper selenide nanoparticles were studied through small-angle neutron scattering (SANS) and transmission electron microscopy. SANS intensities demonstrate the complicated dependence on the scattering…

Mesoscale and Nanoscale Physics · Physics 2021-12-03 V. S. Gurin , A. V. Rutkauskas , Yu. E. Gorshkova , S. E. Kichanov , A. A. Alexeenko , D. P. Kozlenko

From the spread of pollutants in the atmosphere to the transmission of nutrients across cell membranes, anomalous diffusion processes are ubiquitous in natural systems. The ability to understand and control the mechanisms guiding such…

Statistical Mechanics · Physics 2021-01-04 E G Kostadinova , J L Padgett , C D Liaw , L S Matthews , T W Hyde

Polyp segmentation plays a pivotal role in colorectal cancer diagnosis. Recently, the emergence of the Segment Anything Model (SAM) has introduced unprecedented potential for polyp segmentation, leveraging its powerful pre-training…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Huiqian Li , Dingwen Zhang , Jieru Yao , Longfei Han , Zhongyu Li , Junwei Han

To explore dense packings of soft colloids, scattering experiments are ideal to access the structure factor. However, for soft microgels determination of the structure factor is difficult because of the low contrast of the polymer network…

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