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Discovery of novel protein biomarkers for clinical applications is an active research field across a manifold of diseases. Despite some successes and progress, the biomarker development pipeline still frequently ends in failure as biomarker…

Biomolecules · Quantitative Biology 2025-05-01 Katharina Waury

The value of biomedical research--a $1.7 trillion annual investment--is ultimately determined by its downstream, real-world impact. Current objective predictors of impact rest on proxy, reductive metrics of dissemination, such as paper…

While computer modeling and simulation are crucial for understanding scientometrics, their practical use in literature remains somewhat limited. In this study, we establish a joint coauthorship and citation network using preferential…

Digital Libraries · Computer Science 2024-04-22 Haobai Xue

Speech is a rich biomarker that encodes substantial information about the health of a speaker, and thus it has been proposed for the detection of numerous diseases, achieving promising results. However, questions remain about what the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Catarina Botelho , Alberto Abad , Tanja Schultz , Isabel Trancoso

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates…

Understanding the relationship between the composition of a research team and the potential impact of their research papers is crucial as it can steer the development of new science policies for improving the research enterprise. Numerous…

Digital Libraries · Computer Science 2023-07-03 Angelo Salatino , Simone Angioni , Francesco Osborne , Diego Reforgiato Recupero , Enrico Motta

The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Chen Yang , Wang Ziyue , Fang Zijie , Bian Hao , Zhang Yongbing

This paper contributes to the quest for an operational definition of 'research excellence' and proposes a translation of the excellence concept into a bibliometric indicator. Starting from a textual analysis of funding program calls aimed…

Digital Libraries · Computer Science 2013-07-29 Nadine Rons , Lucy Amez

Citation metrics are the best tools for research assessments. However, current metrics may be misleading in research systems that pursue simultaneously different goals, such as the advance of science and incremental innovations, because…

Digital Libraries · Computer Science 2023-09-27 Alonso Rodriguez-Navarro , Ricardo Brito

The development of inventions is theorized as a process of searching and recombining existing knowledge components. Previous studies under this theory have examined myriad characteristics of recombined knowledge and their performance…

Digital Libraries · Computer Science 2024-11-15 Qing Ke , Ziyou Teng , Chao Min

Aim: provide a methodological framework for the process of clinical tests, clinical acceptance, and scientific assessment of algorithms and software based on the artificial intelligence (AI) technologies. Clinical tests are considered as a…

The web application presented in this paper allows for an analysis to reveal centres of excellence in different fields worldwide using publication and citation data. Only specific aspects of institutional performance are taken into account…

Digital Libraries · Computer Science 2013-07-25 Lutz Bornmann , Moritz Stefaner , Felix de Moya Anegon , Ruediger Mutz

Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example…

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

British biophysics has a tradition of scientific invention and innovation, resulting in new technologies transforming biological insight, such as rapid DNA sequencing, super-resolution and label-free microscopy, high-throughput and…

Biological Physics · Physics 2025-06-24 Jack Shepherd , Mark Leake

Medical errors are a major public health concern and a leading cause of death worldwide. Many healthcare centers and hospitals use reporting systems where medical practitioners write a preliminary medical report and the report is later…

Information Retrieval · Computer Science 2020-05-01 Sean MacAvaney , Arman Cohan , Nazli Goharian , Ross Filice

Subject classification schemes are foundational to the organization, evaluation, and navigation of scientific knowledge. While expert-curated systems like Scopus provide widely used taxonomies, they often suffer from coarse granularity,…

Digital Libraries · Computer Science 2025-12-30 Zhuoqi Lyu , Qing Ke

Peer review and citation metrics are two means of gauging the value of scientific research, but the lack of publicly available peer review data makes the comparison of these methods difficult. Mathematics can serve as a useful laboratory…

Digital Libraries · Computer Science 2020-12-17 Lawrence Smolinsky , Daniel S. Sage , Aaron J. Lercher , Aaron Cao

The explosive growth of scientists, scientific journals, articles and findings in recent years exponentially increases the difficulty scientists face in navigating prior knowledge. This challenge is exacerbated by uncertainty about the…

Social and Information Networks · Computer Science 2025-01-27 Alexander V. Belikov , Andrey Rzhetsky , James Evans