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We present a microscopic approach for the coupling of cortical activity, as resulting from proper dipole currents of pyramidal neurons, to the electromagnetic field in extracellular fluid in presence of diffusion and Ohmic conduction.…

Neurons and Cognition · Quantitative Biology 2013-10-08 Peter beim Graben , Serafim Rodrigues

The stochastic FitzHugh-Nagumo (FHN) model is a two-dimensional nonlinear stochastic differential equation with additive degenerate noise, whose first component, the only one observed, describes the membrane voltage evolution of a single…

Computation · Statistics 2024-10-08 Adeline Samson , Massimiliano Tamborrino , Irene Tubikanec

Population rate or activity equations are the foundation of a common approach to modeling for neural networks. These equations provide mean field dynamics for the firing rate or activity of neurons within a network given some connectivity.…

Neurons and Cognition · Quantitative Biology 2009-05-15 Michael A. Buice , Jack D. Cowan , Carson C. Chow

Simulation of extracellular fields is one of the substantial methods used in the area of computational neuroscience. Its most common usage is validation of experimental methods as EEG and extracellular spike recordings or modeling of…

Neurons and Cognition · Quantitative Biology 2013-01-22 Pavol Bauer , Sanja Mikulovic , Stefan Engblom , Katarina E. Leão , Frank Rattay , Richardson N. Leão

This paper introduces a model of excitability that unifies the mechanism of an important neuronal property both in time and in space. As a starting point, we revisit both a key model of temporal excitability, proposed by Hodgkin and Huxley,…

Systems and Control · Electrical Eng. & Systems 2025-05-29 Thomas SJ Burger , Amir Shahhosseini , Rodolphe Sepulchre

Neurons fire irregularly on multiple timescales when stimulated with a periodic pulse train. This raises two questions: Does this irregularity imply significant intrinsic stochasticity? Can existing neuron models be readily extended to…

Cell Behavior · Quantitative Biology 2013-01-14 Daniel Soudry , Ron Meir

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model. Internal noise stemming from the stochastic…

Subcellular Processes · Quantitative Biology 2007-05-23 Gerhard Schmid , Igor Goychuk , Peter Hanggi

Recurrent neural networks are powerful tools for understanding and modeling computation and representation by populations of neurons. Continuous-variable or "rate" model networks have been analyzed and applied extensively for these…

Neurons and Cognition · Quantitative Biology 2016-01-29 Brian DePasquale , Mark M. Churchland , L. F. Abbott

We consider multi-class systems of interacting nonlinear Hawkes processes modeling several large families of neurons and study their mean field limits. As the total number of neurons goes to infinity we prove that the evolution within each…

Probability · Mathematics 2016-10-04 Susanne Ditlevsen , Eva Löcherbach

The diversity of diffusive systems exhibiting long-range correlations characterized by a stochastically varying Hurst exponent calls for a generic multifractional model. We present a simple, analytically tractable model which fills the gap…

The effect of external fluctuations on the formation of spatial patterns is analysed by means of a stochastic Swift-Hohenberg model with multiplicative space-correlated noise. Numerical simulations in two dimensions show a shift of the…

Condensed Matter · Physics 2009-10-28 J. Garcia-Ojalvo , J. M. Sancho

We study the stochastic system of interacting neurons introduced in De Masi et al. (2015) and in Fournier and L\"ocherbach (2016) in a diffusive scaling. The system consists of $N$ neurons, each spiking randomly with rate depending on its…

Probability · Mathematics 2020-03-03 Xavier Erny , Eva Löcherbach , Dasha Loukianova

Subthreshold oscillations in neurons are those oscillations which do not attain the critical value of the membrane's voltage needed for triggering an action potential (a spike). Their contribution to the forming of action potentials in…

Dynamical Systems · Mathematics 2024-03-22 G. Moza , R. Efrem

The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection away from a neuron. Under normal conditions two axonal cytoskeletal polymers microtubules and neurofilaments…

Cell Behavior · Quantitative Biology 2016-02-17 Chuan Xue , Blerta Shtylla , Anthony Brown

A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

Methodology · Statistics 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

Modeling and simulating how oxygen supply shapes neuronal excitability is crucial for advancing the understanding of brain function in pathological scenarios, such as ischemia. This condition is caused by a reduced blood supply, leading to…

Numerical Analysis · Mathematics 2026-03-19 Francesco Daniele , Caterina B. Leimer Saglio , Stefano Pagani , Paola F. Antonietti

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Neurons and Cognition · Quantitative Biology 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

We investigate numerically the collective dynamical behavior of pulse-coupled non-leaky integrate-and-fire-neurons that are arranged on a two-dimensional small-world network. To ensure ongoing activity, we impose a probability for…

Computational Physics · Physics 2012-02-15 Alexander Rothkegel , Klaus Lehnertz

Results are presented from numerical experiments aiming at the computation of stochastic phase-field models for phase transformations by coarse-graining molecular dynamics. The studied phase transformations occur between a solid crystal and…

Numerical Analysis · Mathematics 2009-08-11 Erik von Schwerin