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Pedigrees, or family trees, are graphs of family relationships that are used to study inheritance. A fundamental problem in computational biology is to find, for a pedigree with $n$ individuals genotyped at every site, a set of…

Data Structures and Algorithms · Computer Science 2016-02-16 Bonnie Kirkpatrick

An important and well-studied problem in phylogenetics is to compute a \emph{consensus tree} so as to summarize the common features within a collection of rooted phylogenetic trees, all whose leaf-sets are bijectively labeled by the same…

Populations and Evolution · Quantitative Biology 2021-07-22 Katharina T. Huber , Vincent Moulton , Andreas Spillner

This is a survey article on trees, with a modest number of proofs to give a flavor of the way these topologies can be efficiently handled. Trees are defined in set-theorist fashion as partially ordered sets in which the elements below each…

General Topology · Mathematics 2007-05-23 Peter J. Nyikos

We present an algorithm for phylogenetic reconstruction using quartets that returns the correct topology for $n$ taxa in $O(n \log n)$ time with high probability, in a probabilistic model where a quartet is not consistent with the true…

Populations and Evolution · Quantitative Biology 2010-10-12 Daniel G. Brown , Jakub Truszkowski

Credible intervals and credible sets, such as highest posterior density (HPD) intervals, form an integral statistical tool in Bayesian phylogenetics, both for phylogenetic analyses and for development. Readily available for continuous…

Data Structures and Algorithms · Computer Science 2026-05-05 Jonathan Klawitter , Alexei J. Drummond

In this paper, we lay the groundwork on the comparison of phylogenetic networks based on edge contractions and expansions as edit operations, as originally proposed by Robinson and Foulds to compare trees. We prove that these operations…

Data Structures and Algorithms · Computer Science 2025-02-21 Bertrand Marchand , Nadia Tahiri , Olivier Tremblay-Savard , Manuel Lafond

Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…

Data Structures and Algorithms · Computer Science 2011-10-19 Bonnie Kirkpatrick , Yakir Reshef , Hilary Finucane , Haitao Jiang , Binhai Zhu , Richard M. Karp

The amount of completely sequenced chloroplast genomes increases rapidly every day, leading to the possibility to build large scale phylogenetic trees of plant species. Considering a subset of close plant species defined according to their…

Artificial Intelligence · Computer Science 2015-04-21 Bassam AlKindy , Christophe Guyeux , Jean-François Couchot , Michel Salomon , Christian Parisod , Jacques M. Bahi

Attempting to recognize a tree inside a phylogenetic network is a fundamental undertaking in evolutionary analysis. In the last few years, therefore, tree-based phylogenetic networks, which are defined by a spanning tree called a…

Combinatorics · Mathematics 2020-09-29 Momoko Hayamizu

The statistical estimation of phylogenies is always associated with uncertainty, and accommodating this uncertainty is an important component of modern phylogenetic comparative analysis. The birth-death polytomy resolver is a method of…

Quantitative Methods · Quantitative Biology 2015-03-18 Daniel L. Rabosky

Between the leaves and the nodes of a complete binary tree, a separate parent-child-sister hierarchy is employed independent of the parent-child-sister hierarchy used for the rest of the tree. Two different versions of such a local…

Data Structures and Algorithms · Computer Science 2014-01-31 Mevlut Bulut

Phylogenetic networks generalize phylogenetic trees by allowing the modelization of events of reticulate evolution. Among the different kinds of phylogenetic networks that have been proposed in the literature, the subclass of binary…

Data Structures and Algorithms · Computer Science 2020-07-01 Gabriel Cardona , Joan Carles Pons , Celine Scornavacca

The maximum common subtree isomorphism problem asks for the largest possible isomorphism between subtrees of two given input trees. This problem is a natural restriction of the maximum common subgraph problem, which is ${\sf NP}$-hard in…

Data Structures and Algorithms · Computer Science 2016-08-23 Andre Droschinsky , Nils M. Kriege , Petra Mutzel

The problem of selecting small groups of itemsets that represent the data well has recently gained a lot of attention. We approach the problem by searching for the itemsets that compress the data efficiently. As a compression technique we…

Data Structures and Algorithms · Computer Science 2019-02-08 Nikolaj Tatti , Jilles Vreeken

This paper introduces constNJ, the first algorithm for phylogenetic reconstruction of sets of trees with constrained pairwise rooted subtree-prune regraft (rSPR) distance. We are motivated by the problem of constructing sets of trees which…

Populations and Evolution · Quantitative Biology 2009-09-30 Frederick A. Matsen

An important problem in phylogenetics is the construction of phylogenetic trees. One way to approach this problem, known as the supertree method, involves inferring a phylogenetic tree with leaves consisting of a set $X$ of species from a…

Populations and Evolution · Quantitative Biology 2017-11-21 Katharine T. Huber , Vincent Moulton , Charles Semple , Taoyang Wu

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

Given a set $X$ of species, a phylogenetic tree is an unrooted binary tree whose leaves are bijectively labelled by $X$. Such trees can be used to show the way species evolve over time. One way of understanding how topologically different…

Populations and Evolution · Quantitative Biology 2023-09-01 Steven Kelk , Ruben Meuwese

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

Populations and Evolution · Quantitative Biology 2019-04-09 Erin Molloy , Tandy Warnow

The Persistent-Phylogeny Model is an extension of the widely studied Perfect-Phylogeny Model, encompassing a broader range of evolutionary phenomena. Biological and algorithmic questions concerning persistent phylogeny have been intensely…

Populations and Evolution · Quantitative Biology 2015-06-03 Dan Gusfield