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Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

Machine Learning · Computer Science 2024-09-06 Juan A. Berrios Moya

Alzheimer's disease (AD) persists as a paramount challenge in neurological research, characterized by the pathological hallmarks of amyloid-beta (Abeta) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. This review…

Neurons and Cognition · Quantitative Biology 2025-12-15 Xutong She

Nowadays, scientific challenges usually require approaches that cross traditional boundaries between academic disciplines, driving many researchers towards interdisciplinarity. Despite its obvious importance, there is a lack of studies on…

Physics and Society · Physics 2016-07-25 Elisa Omodei , Manlio De Domenico , Alex Arenas

The majority of common diseases are influenced by multiple genetic and environmental factors such as Cancer. Even though uncovering the main causes of disease is deemed difficult due to the complexity of gene-gene and gene-environment…

Other Computer Science · Computer Science 2017-05-10 Layan Nahlawi

Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research.…

Digital Libraries · Computer Science 2025-12-30 Shahab Mosallaie , Andrea Schiffauerova , Ashkan Ebadi

Understanding the relationship between emerging technology and research and development has long been of interest to companies, policy makers and researchers. In this paper new sources of data and tools are combined with a novel technique…

General Economics · Economics 2023-05-05 Xian Gong , Claire McFarland , Paul McCarthy , Colin Griffith , Marian-Andrei Rizoiu

The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful resource for the…

Quantitative Methods · Quantitative Biology 2011-03-29 Huijun Wang , Ying Ding , Jie Tang , Xiao Dong , Bing He , Judy Qiu , David J. Wild

The Internet of Bio-Nano-Things is a new paradigm that can bring novel remotely controlled actuation and sensing techniques inside the human body. Towards precise bionano sensing techniques in the brain, we investigate the challenges of…

Emerging Technologies · Computer Science 2018-10-23 Michael Taynnan Barros , Walisson Silva , Carlos Danilo Miranda Regis

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…

Link prediction algorithms can help to understand the structure and dynamics of scientific collaborations and the evolution of Science. However, available algorithms based on similarity between nodes of collaboration networks are bounded by…

Physics and Society · Physics 2020-11-25 Marta Tuninetti , Alberto Aleta , Daniela Paolotti , Yamir Moreno , Michele Starnini

This article presents a novel method for causal discovery with generalized structural equation models suited for analyzing diverse types of outcomes, including discrete, continuous, and mixed data. Causal discovery often faces challenges…

Methodology · Statistics 2023-10-26 Minjie Wang , Xiaotong Shen , Wei Pan

A major challenge in biomedical data science is to identify the causal genes underlying complex genetic diseases. Despite the massive influx of genome sequencing data, identifying disease-relevant genes remains difficult as individuals with…

Genomics · Quantitative Biology 2020-01-20 Borislav H. Hristov , Bernard Chazelle , Mona Singh

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

Alzheimer's disease (AD) persists as a paramount challenge in neurological research, characterized by the pathological hallmarks of amyloid-$\beta$ (A$\beta$) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. This…

Molecular Networks · Quantitative Biology 2025-12-05 She Xutong

In scientific research, collaboration is one of the most effective ways to take advantage of new ideas, skills, resources, and for performing interdisciplinary research. Although collaboration networks have been intensively studied, the…

Digital Libraries · Computer Science 2022-09-14 An Zeng , Ying Fan , Zengru Di , Yougui Wang , Shlomo Havlin

Navigating the vast and rapidly increasing sea of academic publications to identify institutional synergies, benchmark research contributions and pinpoint key research contributions has become an increasingly daunting task, especially with…

Digital Libraries · Computer Science 2025-09-09 Moritz Staudinger , Wojciech Kusa , Matteo Cancellieri , David Pride , Petr Knoth , Allan Hanbury

Information integration plays a pivotal role in biomedical studies by facilitating the combination and analysis of independent datasets from multiple studies, thereby uncovering valuable insights that might otherwise remain obscured due to…

Methodology · Statistics 2024-07-02 Chixiang Chen , Jia Liang , Elynn Chen , Ming Wang

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

The current clinical diagnosis framework of Alzheimer's disease (AD) involves multiple modalities acquired from multiple diagnosis stages, each with distinct usage and cost. Previous AD diagnosis research has predominantly focused on how to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 Yuxiao Liu , Mianxin Liu , Yuanwang Zhang , Kaicong Sun , Dinggang Shen