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We use HIP-NN, a neural network architecture that excels at predicting molecular energies, to predict atomic charges. The charge predictions are accurate over a wide range of molecules (both small and large) and for a diverse set of charge…

The ability to accurately model interatomic interactions in large-scale systems is fundamental to understanding a wide range of physical and chemical phenomena, from drug-protein binding to the behavior of next-generation materials. While…

Materials Science · Physics 2025-05-26 Taskin Mehereen , Sourav Saha , Intesar Jawad Jaigirdar , Chanwook Park

We present a neural network (NN) potential based on a new set of atomic fingerprints built upon two- and three-body contributions that probe distances and local orientational order respectively. Compared to existing NN potentials, the…

Soft Condensed Matter · Physics 2023-03-22 Francesco Guidarelli Mattioli , Francesco Sciortino , John Russo

Existing adaptive bias techniques, which seek to estimate free energies and physical properties from molecular simulations, are limited by their reliance on fixed kernels or basis sets which hinder their ability to efficiently conform to…

Statistical Mechanics · Physics 2018-04-04 Hythem Sidky , Jonathan K. Whitmer

Density Functional Theory (DFT) has been a cornerstone in computational science, providing powerful insights into structure-property relationships for molecules and materials through first-principles quantum-mechanical (QM) calculations.…

Chemical Physics · Physics 2024-08-13 Yicheng Chen , Wenjie Yan , Zhanfeng Wang , Jianming Wu , Xin Xu

Deep artificial neural networks are powerful tools with many possible applications in nanophotonics. Here, we demonstrate how a deep neural network can be used as a fast, general purpose predictor of the full near-field and far-field…

Computational Physics · Physics 2020-01-28 Peter R. Wiecha , Otto L. Muskens

The large computing and memory cost of deep neural networks (DNNs) often precludes their use in resource-constrained devices. Quantizing the parameters and operations to lower bit-precision offers substantial memory and energy savings for…

Machine Learning · Computer Science 2023-09-01 Clemens JS Schaefer , Siddharth Joshi , Shan Li , Raul Blazquez

Accuracy of molecular dynamics simulations depends crucially on the interatomic potential used to generate forces. The gold standard would be first-principles quantum mechanics (QM) calculations, but these become prohibitively expensive at…

Modern applications of atomic physics, including the determination of frequency standards, and the analysis of astrophysical spectra, require prediction of atomic properties with exquisite accuracy. For complex atomic systems,…

Atomic Physics · Physics 2024-08-02 Pavlo Bilous , Charles Cheung , Marianna Safronova

Interatomic potentials learned using machine learning methods have been successfully applied to atomistic simulations. However, accurate models require large training datasets, while generating reference calculations is computationally…

Machine Learning · Computer Science 2024-01-23 John Falk , Luigi Bonati , Pietro Novelli , Michele Parrinello , Massimiliano Pontil

Atomic neural networks (ANNs) constitute a class of machine learning methods for predicting potential energy surfaces and physico-chemical properties of molecules and materials. Despite many successes, developing interpretable ANN…

Computational Physics · Physics 2020-01-17 Yunqi Shao , Matti Hellström , Pavlin D. Mitev , Lisanne Knijff , Chao Zhang

Molecular modeling is an important topic in drug discovery. Decades of research have led to the development of high quality scalable molecular force fields. In this paper, we show that neural networks can be used to train a universal…

Quantitative Methods · Quantitative Biology 2021-04-20 Ke Liu , Zekun Ni , Zhenyu Zhou , Suocheng Tan , Xun Zou , Haoming Xing , Xiangyan Sun , Qi Han , Junqiu Wu , Jie Fan

Spiking neural networks (SNNs) have great potential for energy-efficient implementation of Deep Neural Networks (DNNs) on dedicated neuromorphic hardware. Recent studies demonstrated competitive performance of SNNs compared with DNNs on…

Neural and Evolutionary Computing · Computer Science 2020-12-24 Weihao Tan , Devdhar Patel , Robert Kozma

We demonstrate that a committee of deep neural networks is capable of predicting the ground-state and excited energies of more than 1800 atomic nuclei with an accuracy akin to the one achieved by state-of-the-art nuclear energy density…

Nuclear Theory · Physics 2020-04-29 R. -D. Lasseri , D. Regnier , J. -P. Ebran , A. Penon

An interatomic potential for Al-Tb alloy around the composition of Al90Tb10 was developed using the deep neural network (DNN) learning method. The atomic configurations and the corresponding total potential energies and forces on each atom…

Materials Science · Physics 2023-07-19 L. Tang , Z. J. Yang , T. Q. Wen , K. M. Ho , M. J. Kramer , C. Z. Wang

The discovery and optimization of high-energy materials (HEMs) are constrained by the prohibitive computational expense and prolonged development cycles inherent in conventional approaches. In this work, we develop a general neural network…

Materials Science · Physics 2025-03-05 Mingjie Wen , Jiahe Han , Wenjuan Li , Xiaoya Chang , Qingzhao Chu , Dongping Chen

Deep learning techniques have opened a new venue for electronic structure theory in recent years. In contrast to traditional methods, deep neural networks provide much more expressive and flexible wave function ansatz, resulting in better…

Chemical Physics · Physics 2021-09-08 Xiang Li , Cunwei Fan , Weiluo Ren , Ji Chen

Machine-learning models in chemistry - when based on descriptors of atoms embedded within molecules - face essential challenges in transferring the quality of predictions of local electronic structures and their associated properties across…

Chemical Physics · Physics 2024-09-27 Frederik Ø. Kjeldal , Janus J. Eriksen

The rapid scaling of deep neural networks comes at the cost of unsustainable power consumption. While optical neural networks offer an alternative, their capabilities remain constrained by the lack of efficient optical nonlinearities. To…

Optics · Physics 2026-01-06 Qingyi Zhou , Jungmin Kim , Yutian Tao , Guoming Huang , Ming Zhou , Zewei Shao , Zongfu Yu

We present large-scale molecular dynamics (MD) simulations based on a machine-learning interatomic potential to investigate the wet etching behavior of various GaN facets in alkaline solution-a process critical to the fabrication of…

Materials Science · Physics 2025-05-14 Purun-hanul Kim , Jeong Min Choi , Seungwu Han , Youngho Kang