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We study a stochastic multiscale spatial gene network. These naturally arise in molecular biology. In our model, the reactants are subject to on-site reactions on both scales and diffusion on the continuous scale only, although diffusion on…

Probability · Mathematics 2026-04-01 Arnaud Debussche , Baptiste Huguet

Gaussian Process state-space models capture complex temporal dependencies in a principled manner by placing a Gaussian Process prior on the transition function. These models have a natural interpretation as discretized stochastic…

Machine Learning · Computer Science 2022-02-24 Krista Longi , Jakob Lindinger , Olaf Duennbier , Melih Kandemir , Arto Klami , Barbara Rakitsch

The paper addresses the problem of calculating the noise-induced switching rates in systems with delay-distributed kernels and Gaussian noise. A general variational formulation for the switching rate is derived for any distribution kernel,…

Data Analysis, Statistics and Probability · Physics 2018-07-04 Y. N. Kyrychko , I. B. Schwartz

We present a framework and algorithms to learn controlled dynamics models using neural stochastic differential equations (SDEs) -- SDEs whose drift and diffusion terms are both parametrized by neural networks. We construct the drift term to…

Machine Learning · Computer Science 2023-10-17 Franck Djeumou , Cyrus Neary , Ufuk Topcu

In this paper, we present the discrete-time unbiased extremum seeking (ES) algorithm for n-dimensional (nD) static quadratic maps in the presence of unknown time-varying measurement delays bounded by known constants which can be large. The…

Optimization and Control · Mathematics 2026-04-07 Adam Jbara , Emilia Fridman , Xuefei Yang

Stochastic differential equations (SDEs) are popular tools to analyse time series data in many areas, such as mathematical finance, physics, and biology. They provide a mechanistic description of the phenomeon of interest, and their…

Methodology · Statistics 2021-02-01 Théo Michelot , Richard Glennie , Catriona Harris , Len Thomas

Dynamical phase transitions are crucial features of the fluctuations of statistical systems, corresponding to boundaries between qualitatively different mechanisms of maintaining unlikely values of dynamical observables over long periods of…

Statistical Mechanics · Physics 2017-06-02 Alexandre Lazarescu

Tracer diffusion in single-file systems, where particles are restricted to move on a line without passing each other, has been a fertile ground to investigate anomalous diffusion and strong memory effects. While the long-time behavior of…

Statistical Mechanics · Physics 2025-05-28 Alexis Poncet , Aurélien Grabsch , Olivier Bénichou

System identification is of special interest in science and engineering. This article is concerned with a system identification problem arising in stochastic dynamic systems, where the aim is to estimate the parameters of a system along…

Methodology · Statistics 2022-01-27 Christos Merkatas , Simo Särkkä

Gaussian macroscopic fluctuation theory underpins the understanding of noise in a broad class of nonequilibrium systems. We derive exact fluctuation-response relations linking the power spectral density of stationary fluctuations to the…

Statistical Mechanics · Physics 2026-02-11 Timur Aslyamov , Krzysztof Ptaszyński , Massimiliano Esposito

Dynamic gene-regulatory networks are complex since the number of potential components involved in the system is very large. Estimating dynamic networks is an important task because they compromise valuable information about interactions…

Methodology · Statistics 2012-05-15 Antonino Abbruzzo , Ernst Wit

We propose here a method to estimate a delay from a time series taking advantage of analysis of random walks with delay. This method is applicable to a time series coming out of a system which is or can be approximated as a linear feedback…

Statistical Mechanics · Physics 2009-10-30 Toru Ohira , Ryusuke Sawatari

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

We consider a jump-diffusion process on a bounded domain with reflection at the boundary, and establish long-term results for a general additive process of its path. This includes the long-term behaviour of its occupation time in the…

Probability · Mathematics 2022-07-29 Lea Popovic , Giovanni Zoroddu

Diffusion models achieve state-of-the-art generation quality across many applications, but their ability to capture rare or extreme events in heavy-tailed distributions remains unclear. In this work, we show that traditional diffusion and…

Machine Learning · Computer Science 2024-10-30 Kushagra Pandey , Jaideep Pathak , Yilun Xu , Stephan Mandt , Michael Pritchard , Arash Vahdat , Morteza Mardani

We introduce simple models of genetic regulatory networks and we proceed to the mathematical analysis of their dynamics. The models are discrete time dynamical systems generated by piecewise affine contracting mappings whose variables…

Dynamical Systems · Mathematics 2007-05-23 Ricardo Coutinho , Bastien Fernandez , Ricardo Lima , Arnaud Meyroneinc

In this work, we explore modeling change points in time-series data using neural stochastic differential equations (neural SDEs). We propose a novel model formulation and training procedure based on the variational autoencoder (VAE)…

Machine Learning · Computer Science 2025-06-16 Yousef El-Laham , Zhongchang Sun , Haibei Zhu , Tucker Balch , Svitlana Vyetrenko

We prove the dynamical large deviations for a particle system in which particles may have different velocities. We assume that we have two infinite reservoirs of particles at the boundary: this is the so-called boundary driven process. The…

Probability · Mathematics 2010-06-02 Jonathan Farfan , Alexandre B. Simas , Fabio J. Valentim

Are there hidden dynamical common patterns in the evolution of social and cultural history? While the growing availability of digitized social data invites us to answer this question, prevailing quantitative methods often rely on…

Social and Information Networks · Computer Science 2026-01-27 Youngkyoung Bae , Hajime Shimao , Seungwoong Ha , Luna Yang , David Wolpert

Landscape is one of the key notions in literature on biological processes and physics of complex systems with both deterministic and stochastic dynamics. The large deviation theory (LDT) provides a possible mathematical basis for the…

Mathematical Physics · Physics 2012-06-19 Hao Ge , Hong Qian
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