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Genome-wide association studies (GWA studies or GWAS) investigate the relationships between genetic variants such as single-nucleotide polymorphisms (SNPs) and individual traits. Recently, incorporating biological priors together with…

Machine Learning · Statistics 2017-09-13 Tao Yang , Paul Thompson , Sihai Zhao , Jieping Ye

Recent technological developments have enabled us to collect complex and high-dimensional data in many scientific fields, such as population health, meteorology, econometrics, geology, and psychology. It is common to encounter such datasets…

Methodology · Statistics 2020-03-16 Ufuk Beyaztas , Han Lin Shang

High-dimensional multivariate longitudinal data, which arise when many outcome variables are measured repeatedly over time, are becoming increasingly common in social, behavioral and health sciences. We propose a latent variable model for…

Methodology · Statistics 2025-12-09 Sze Ming Lee , Yunxiao Chen , Tony Sit

Graphical models describe associations between variables through the notion of conditional independence. Gaussian graphical models are a widely used class of such models where the relationships are formalized by non-null entries of the…

Methodology · Statistics 2023-08-08 Sagnik Bhadury , Riten Mitra , Jeremy T. Gaskins

Functional data contains two components: shape (or amplitude) and phase. This paper focuses on a branch of functional data analysis (FDA), namely Shape-Based FDA, that isolates and focuses on shapes of functions. Specifically, this paper…

Methodology · Statistics 2024-11-26 Sayan Bhadra , Anuj Srivastava

In clinical trials, identification of prognostic and predictive biomarkers is essential to precision medicine. Prognostic biomarkers can be useful for the prevention of the occurrence of the disease, and predictive biomarkers can be used to…

Methodology · Statistics 2022-06-28 Wencan Zhu , Céline Lévy-Leduc , Nils Ternès

An approach to inference for relative sparsity was developed in prior work, and an adaptive lasso asymptotic normality theorem was given there, but this theorem was not fully used when estimating the variance of the policy coefficients.…

Methodology · Statistics 2026-05-05 Samuel Julian Weisenthal

A new estimator, named S-LASSO, is proposed for the coefficient function of the Function-on-Function linear regression model. The S-LASSO estimator is shown to be able to increase the interpretability of the model, by better locating…

Methodology · Statistics 2022-07-15 Fabio Centofanti , Matteo Fontana , Antonio Lepore , Simone Vantini

We establish oracle inequalities for a version of the Lasso in high-dimensional fixed effects dynamic panel data models. The inequalities are valid for the coefficients of the dynamic and exogenous regressors. Separate oracle inequalities…

Statistics Theory · Mathematics 2016-01-05 Anders Bredahl Kock , Haihan Tang

Effect modification occurs when the effect of the treatment on an outcome differs according to the level of a third variable (the effect modifier, EM). A natural way to assess effect modification is by subgroup analysis or include the…

Methodology · Statistics 2021-12-22 Asma Bahamyirou , Mireille E. Schnitzer , Edward H. Kennedy , Lucie Blais , Yi Yang

Massive data bring the big challenges of memory and computation for analysis. These challenges can be tackled by taking subsamples from the full data as a surrogate. For functional data, it is common to collect multiple measurements over…

Methodology · Statistics 2021-07-07 Hua Liu , Jinhong You , Jiguo Cao

Neuroimage analysis usually involves learning thousands or even millions of variables using only a limited number of samples. In this regard, sparse models, e.g. the lasso, are applied to select the optimal features and achieve high…

Machine Learning · Computer Science 2015-03-26 Bo Xin , Lingjing Hu , Yizhou Wang , Wen Gao

Sparse variational approximations are popular methods for scaling up inference and learning in Gaussian processes to larger datasets. For $N$ training points, exact inference has $O(N^3)$ cost; with $M \ll N$ features, state of the art…

Machine Learning · Statistics 2024-04-15 Talay M Cheema , Carl Edward Rasmussen

In a polynomial regression model, the divisibility conditions implicit in polynomial hierarchy give way to a natural construction of constraints for the model parameters. We use this principle to derive versions of strong and weak hierarchy…

Computation · Statistics 2020-01-23 Hugo Maruri-Aguilar , Simon Lunagomez

There has been much recent work on inference after model selection when the noise level is known, however, $\sigma$ is rarely known in practice and its estimation is difficult in high-dimensional settings. In this work we propose using the…

Statistics Theory · Mathematics 2017-02-13 Xiaoying Tian , Joshua R. Loftus , Jonathan E. Taylor

We propose a general family of algorithms for regression estimation with quadratic loss. Our algorithms are able to select relevant functions into a large dictionary. We prove that a lot of algorithms that have already been studied for this…

Statistics Theory · Mathematics 2008-11-25 Pierre Alquier

Inference for high-dimensional logistic regression models using penalized methods has been a challenging research problem. As an illustration, a major difficulty is the significant bias of the Lasso estimator, which limits its direct…

Methodology · Statistics 2024-10-29 Yuming Zhang , Stéphane Guerrier , Runze Li

This paper develops a new framework, called modular regression, to utilize auxiliary information -- such as variables other than the original features or additional data sets -- in the training process of linear models. At a high level, our…

Methodology · Statistics 2023-11-27 Ying Jin , Dominik Rothenhäusler

This paper considers quantile model with grouped explanatory variables. In order to have the sparsity of the parameter groups but also the sparsity between two successive groups of variables, we propose and study an adaptive fused group…

Statistics Theory · Mathematics 2016-07-20 Gabriela Ciuperca

We develop tools for selective inference in the setting of group sparsity, including the construction of confidence intervals and p-values for testing selected groups of variables. Our main technical result gives the precise distribution of…

Methodology · Statistics 2016-07-28 Fan Yang , Rina Foygel Barber , Prateek Jain , John Lafferty
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