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We propose a whole-body model of the metabolism in man as well as a generalized approach for modeling metabolic networks. Using this approach, we are able to write a large metabolic network in a systematic and compact way. We demonstrate…

Quantitative Methods · Quantitative Biology 2022-05-04 Peter Emil Carstensen , Jacob Bendsen , Asbjørn Thode Reenberg , Tobias K. S. Ritschel , John Bagterp Jørgensen

Capturing users' precise preferences is of great importance in various recommender systems (eg., e-commerce platforms), which is the basis of how to present personalized interesting product lists to individual users. In spite of significant…

Information Retrieval · Computer Science 2021-10-11 Lianghao Xia , Chao Huang , Yong Xu , Peng Dai , Bo Zhang , Liefeng Bo

We consider the multi-label ranking approach to multi-label learning. Boosting is a natural method for multi-label ranking as it aggregates weak predictions through majority votes, which can be directly used as scores to produce a ranking…

Machine Learning · Statistics 2018-02-27 Young Hun Jung , Ambuj Tewari

Metabolic networks, formed by a series of metabolic pathways, are made of intracellular and extracellular reactions that determine the biochemical properties of a cell, and by a set of interactions that guide and regulate the activity of…

Logic in Computer Science · Computer Science 2020-08-24 Jean-Marc Alliot , Marta Cialdea Mayer , Robert Demolombe , Martín Diéguez , Luis Fariñas del Cerro

Supervised machine learning often operates on the data-driven paradigm, wherein internal model parameters are autonomously optimized to converge predicted outputs with the ground truth, devoid of explicitly programming rules or a priori…

Machine Learning · Computer Science 2024-12-12 Daniel Geissler , Bo Zhou , Mengxi Liu , Paul Lukowicz

Parallel imaging, a fast MRI technique, involves dynamic adjustments based on the configuration i.e. number, positioning, and sensitivity of the coils with respect to the anatomy under study. Conventional deep learning-based image…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Sriprabha Ramanarayanan , Mohammad Al Fahim , Rahul G. S. , Amrit Kumar Jethi , Keerthi Ram , Mohanasankar Sivaprakasam

Boosting is a learning scheme that combines weak prediction rules to produce a strong composite estimator, with the underlying intuition that one can obtain accurate prediction rules by combining "rough" ones. Although boosting is proved to…

Machine Learning · Computer Science 2015-05-07 Shaobo Lin , Yao Wang , Lin Xu

Modeling and optimization of metabolic networks has been one of the hottest topics in computational systems biology within recent years. However, the complexity and uncertainty of these networks in addition to the lack of necessary data has…

Molecular Networks · Quantitative Biology 2014-07-01 Erfan Khaji , Mahsa Mortazavi

Repeating patterns of spike sequences from a neuronal network have been proposed to be useful in the reconstruction of the network topology. Reverberations in a physiologically realistic model with various physical connection topologies…

Neurons and Cognition · Quantitative Biology 2014-07-15 Hao Song , Chun-Chung Chen , Jyh-Jang Sun , Pik-Yin Lai , C. K. Chan

Drug discovery is crucial for identifying candidate drugs for various diseases.However, its low success rate often results in a scarcity of annotations, posing a few-shot learning problem. Existing methods primarily focus on single-scale…

Machine Learning · Computer Science 2025-02-19 Ruifeng Li , Mingqian Li , Wei Liu , Yuhua Zhou , Xiangxin Zhou , Yuan Yao , Qiang Zhang , Hongyang Chen

A matrix network is a family of matrices, with relatedness modeled by a weighted graph. We consider the task of completing a partially observed matrix network. We assume a novel sampling scheme where a fraction of matrices might be…

Machine Learning · Computer Science 2018-06-11 Qingyun Sun , Mengyuan Yan David Donoho , Stephen Boyd

Many real world, complex phenomena have underlying structures of evolving networks where nodes and links are added and removed over time. A central scientific challenge is the description and explanation of network dynamics, with a key test…

Physics and Society · Physics 2014-08-15 Catherine A. Bliss , Morgan R. Frank , Christopher M. Danforth , Peter Sheridan Dodds

Predicting compound-protein affinity is critical for accelerating drug discovery. Recent progress made by machine learning focuses on accuracy but leaves much to be desired for interpretability. Through molecular contacts underlying…

Biomolecules · Quantitative Biology 2020-01-01 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Link prediction in complex networks has attracted increasing attention from both physical and computer science communities. The algorithms can be used to extract missing information, identify spurious interactions, evaluate network evolving…

Physics and Society · Physics 2015-05-20 Linyuan Lu , Tao Zhou

Multilayer networks offer a powerful framework for modeling complex systems across diverse domains, effectively capturing multiple types of connections and interdependent subsystems commonly found in real world scenarios. To analyze these…

Social and Information Networks · Computer Science 2026-02-20 Martin Guillemaud , Vera Dinkelacker , Mario Chavez

Class-imbalanced data, in which some classes contain far more samples than others, is ubiquitous in real-world applications. Standard techniques for handling class-imbalance usually work by training on a re-weighted loss or on re-balanced…

Artificial Intelligence · Computer Science 2021-06-18 Arpit Bansal , Micah Goldblum , Valeriia Cherepanova , Avi Schwarzschild , C. Bayan Bruss , Tom Goldstein

Link prediction, a foundational task in complex network analysis, has extensive applications in critical scenarios such as social recommendation, drug target discovery, and knowledge graph completion. However, existing evaluations of…

Other Statistics · Statistics 2025-12-30 Yilin Bi , Junhao Bian , Shuyan Wan , Shuaijia Wang , Tao Zhou

Link prediction is one of the most productive branches in network science, aiming to predict links that would have existed but have not yet been observed, or links that will appear during the evolution of the network. Over nearly two…

Social and Information Networks · Computer Science 2024-10-01 Shuyan Wan , Yilin Bi , Xinshan Jiao , Tao Zhou

Relation extraction has been widely studied to extract new relational facts from open corpus. Previous relation extraction methods are faced with the problem of wrong labels and noisy data, which substantially decrease the performance of…

Information Retrieval · Computer Science 2018-05-01 Dongdong Yang , Senzhang Wang , Zhoujun Li

We present a statistical approach for the discovery of relationships between mathematical entities that is based on linear regression and deep learning with fully connected artificial neural networks. The strategy is applied to…

Geometric Topology · Mathematics 2022-04-28 Daniel Grünbaum