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Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Despite the versatility of generalized linear mixed models in handling complex experimental designs, they often suffer from misspecification and convergence problems. This makes inference on the values of coefficients problematic. To…

Methodology · Statistics 2025-03-31 Angela Andreella , Jelle Goeman , Jesse Hemerik , Livio Finos

Ordinary differential equation models facilitate the understanding of cellular signal transduction and other biological processes. However, for large and comprehensive models, the computational cost of simulating or calibrating can be…

Quantitative Methods · Quantitative Biology 2023-11-29 Fabian Fröhlich , Daniel Weindl , Yannik Schälte , Dilan Pathirana , Łukasz Paszkowski , Glenn Terje Lines , Paul Stapor , Jan Hasenauer

We consider the problem of modeling cardiovascular responses to physical activity and sleep changes captured by wearable sensors in free living conditions. We use an attentional convolutional neural network to learn parsimonious signatures…

Machine Learning · Computer Science 2018-12-06 Haraldur T. Hallgrímsson , Filip Jankovic , Tim Althoff , Luca Foschini

Regression learning is classic and fundamental for medical image analysis. It provides the continuous mapping for many critical applications, like the attribute estimation, object detection, segmentation and non-rigid registration. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Chaoyu Chen , Xin Yang , Ruobing Huang , Xindi Hu , Yankai Huang , Xiduo Lu , Xinrui Zhou , Mingyuan Luo , Yinyu Ye , Xue Shuang , Juzheng Miao , Yi Xiong , Dong Ni

In the last decade, research on artificial intelligence has seen rapid growth with deep learning models, especially in the field of medical image segmentation. Various studies demonstrated that these models have powerful prediction…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Dominik Müller , Iñaki Soto-Rey , Frank Kramer

Artificial intelligence (AI) is increasingly being utilized to optimize magnetic resonance imaging (MRI) protocols. Given that image details are critical for diagnostic accuracy, optimizing MRI acquisition protocols is essential for…

Machine Learning · Computer Science 2025-02-05 Alice Vian , Diego Andre Eifer , Mauricio Anes , Guilherme Ribeiro Garcia , Mariana Recamonde-Mendoza

We propose a new segmentation evaluation metric, called segmentation similarity (S), that quantifies the similarity between two segmentations as the proportion of boundaries that are not transformed when comparing them using edit distance,…

Computation and Language · Computer Science 2012-06-08 Chris Fournier , Diana Inkpen

In an interlaboratory key comparison, a data analysis procedure for this comparison was proposed and recommended by CIPM [1, 2, 3], therein the degrees of equivalence of measurement standards of the laboratories participated in the…

Other Statistics · Statistics 2011-12-14 Thang H. Le , Nguyen D. Do

In many practical settings one can sequentially and adaptively guide the collection of future data, based on information extracted from data collected previously. These sequential data collection procedures are known by different names,…

Statistics Theory · Mathematics 2013-11-28 Ervin Tánczos , Rui M. Castro

Clinical diagnosis of meniscus injuries requires radiologists to integrate volumetric MRI evidence with patient context (e.g., sex, age, BMI) and to produce structured diagnostic reports. Existing knee MRI benchmarks are typically unimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Shurui Xu , Siqi Yang , Weiping Ding , Hui Wang , Mengzhen Fan , Yuyu Sun , Shuyan Li

Suppose (standardized) measurements or statistics are monitored to raise an alarm when a threshold is exceeded. Often, the underlying population is heterogenous with respect to important discrete variables and thus samples may consist of…

Statistics Theory · Mathematics 2025-10-10 Ansgar Steland

Spinal cord injury (SCI) is a debilitating condition that often results in significant motor and sensory deficits, impacting the quality of life. Current rehabilitation methods, including physical therapy and electrical stimulation, offer…

Neurons and Cognition · Quantitative Biology 2024-12-18 Ruidong Cheng , Yuling Shao , Xi Li , Li Zhang , Zehao Sheng , Chenyang Li , Xu Xie , Huilin Mou , Weidong Chen , Shaomin Zhang , Yuchen Xu , Minmin Wang

Over the years, there has been growing interest in using Machine Learning techniques for biomedical data processing. When tackling these tasks, one needs to bear in mind that biomedical data depends on a variety of characteristics, such as…

Machine Learning · Computer Science 2020-02-05 Elisa Ferrari , Alessandra Retico , Davide Bacciu

The journal impact factor is not comparable among fields of science and social science because of systematic differences in publication and citation behaviour across disciplines. In this work, a source normalization of the journal impact…

This paper presents a novel quantitative approach for comparative economic studies, addressing limitations in current classification methods. Conventional approaches in comparative economics often rely on ad hoc and categorical…

General Economics · Economics 2025-12-24 Ali Zeytoon-Nejad

Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

Applications · Statistics 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

When assessing the causal effect of a binary exposure using observational data, confounder imbalance across exposure arms must be addressed. Matching methods, including propensity score-based matching, can be used to deconfound the causal…

Methodology · Statistics 2024-10-01 Ernesto Ulloa-Pérez , Marco Carone , Alex Luedtke

Medical imaging classifiers can achieve high predictive accuracy, but quantifying their uncertainty remains an unresolved challenge, which prevents their deployment in medical clinics. We present an algorithm that can modify any classifier…

Machine Learning · Computer Science 2024-08-12 Roy Hirsch , Jacob Goldberger

This note proposes a method, which can be applied to searches and more in general to any cross section measurement, to maximize the analysis sensitivity.

High Energy Physics - Experiment · Physics 2007-05-23 A. Favara , M. Pieri