English
Related papers

Related papers: Penalized Variable Selection for Multi-center Comp…

200 papers

Variable selection is fundamental to high-dimensional statistical modeling. Many variable selection techniques may be implemented by maximum penalized likelihood using various penalty functions. Optimizing the penalized likelihood function…

Statistics Theory · Mathematics 2007-06-13 David R. Hunter , Runze Li

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

Methodology · Statistics 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

Datasets for training recommender systems are often subject to distribution shift induced by users' and recommenders' selection biases. In this paper, we study the impact of selection bias on datasets with different quantization. We then…

Information Retrieval · Computer Science 2022-12-29 Fengyu Li , Sarah Dean

Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…

Methodology · Statistics 2022-06-27 Julien St-Pierre , Karim Oualkacha , Sahir Rai Bhatnagar

In machine learning, incorporating more data is often seen as a reliable strategy for improving model performance; this work challenges that notion by demonstrating that the addition of external datasets in many cases can hurt the resulting…

Machine Learning · Computer Science 2023-08-09 Rhys Compton , Lily Zhang , Aahlad Puli , Rajesh Ranganath

Data sharing barriers are paramount challenges arising from multicenter clinical trials where multiple data sources are stored in a distributed fashion at different local study sites. Merging such data sources into a common data storage for…

Methodology · Statistics 2022-04-05 Mengtong Hu , Xu Shi , Peter X. -K. Song

High-dimensional variable selection in the proportional hazards (PH) model has many successful applications in different areas. In practice, data may involve confounding variables that do not satisfy the PH assumption, in which case the…

Computation · Statistics 2018-03-22 Emily Morris , Kevin He , Yanming Li , Yi Li , Jian Kang

We encounter variables with little variation often in educational data mining (EDM) due to the demographics of higher education and the questions we ask. Yet, little work has examined how to analyze such data. Therefore, we conducted a…

Methodology · Statistics 2022-01-12 Nicholas T. Young , Marcos D. Caballero

Credit risk forecasting plays a crucial role for commercial banks and other financial institutions in granting loans to customers and minimise the potential loss. However, traditional machine learning methods require the sharing of…

Machine Learning · Computer Science 2024-01-17 Shuyao Zhang , Jordan Tay , Pedro Baiz

Accurately assessing a patient's risk of a given event is essential in making informed treatment decisions. One approach is to stratify patients into two or more distinct risk groups with respect to a specific outcome using both clinical…

Methodology · Statistics 2015-03-17 Karen Lostritto , Robert Strawderman , Annette Molinaro

Density regression characterizes the conditional density of the response variable given the covariates, and provides much more information than the commonly used conditional mean or quantile regression. However, it is often computationally…

Methodology · Statistics 2022-06-15 Yunlu Chen , Nan Zhang

In this paper, we introduce a novel combined reward cum penalty loss function to handle the regression problem. The proposed combined reward cum penalty loss function penalizes the data points which lie outside the $\epsilon$-tube of the…

Machine Learning · Computer Science 2020-05-05 Pritam Anand , Reshma Rastogi , Suresh Chandra

We develop methodology for causal inference in observational studies when using propensity score subclassification on data constructed with probabilistic record linkage techniques. We focus on scenarios where covariates and binary treatment…

Methodology · Statistics 2018-04-03 Joan Heck Wortman , Jerome P. Reiter

Variable selection has been widely used in data analysis for the past decades, and it becomes increasingly important in the Big Data era as there are usually hundreds of variables available in a dataset. To enhance interpretability of a…

Methodology · Statistics 2020-08-17 Yuxiang Xie , Kwun Chuen Gary Chan

Federated or multi-site studies have distinct advantages over single-site studies, including increased generalizability, the ability to study underrepresented populations, and the opportunity to study rare exposures and outcomes. However,…

Machine Learning · Statistics 2023-09-25 Larry Han , Zhu Shen , Jose Zubizarreta

Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another…

Machine Learning · Computer Science 2022-07-07 Mohammadreza Nemati , Haonan Zhang , Michael Sloma , Dulat Bekbolsynov , Hong Wang , Stanislaw Stepkowski , Kevin S. Xu

The kidney paired donation (KPD) program provides an innovative solution to overcome incompatibility challenges in kidney transplants by matching incompatible donor-patient pairs and facilitating kidney exchanges. To address unequal access…

Methodology · Statistics 2026-01-21 Mingrui Zhang , Xiaowu Dai , Lexin Li

Accurate time-to-event prediction is integral to decision-making, informing medical guidelines, hiring decisions, and resource allocation. Survival analysis, the quantitative framework used to model time-to-event data, accounts for patients…

Machine Learning · Computer Science 2025-08-08 Vincent Jeanselme , Brian Tom , Jessica Barrett

In cancer epidemiology using population-based data, regression models for the excess mortality hazard is a useful method to estimate cancer survival and to describe the association between prognosis factors and excess mortality. This method…

Methodology · Statistics 2019-04-19 Francisco J. Rubio , Bernard Rachet , Roch Giorgi , Camille Maringe , Aurelien Belot

Covariate imbalance between treatment groups makes it difficult to compare cumulative incidence curves in competing risk analyses. In this paper we discuss different methods to estimate adjusted cumulative incidence curves including inverse…