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Challenging research in various fields has driven a wide range of methodological advances in variable selection for regression models with high-dimensional predictors. In comparison, selection of nonlinear functions in models with additive…

Methodology · Statistics 2013-03-05 Fabian Scheipl , Thomas Kneib , Ludwig Fahrmeir

Penalized regression methods, such as lasso and elastic net, are used in many biomedical applications when simultaneous regression coefficient estimation and variable selection is desired. However, missing data complicates the…

A kidney exchange program, also called a kidney paired donation program, can be viewed as a repeated, dynamic trading and allocation mechanism. This suggests that a dynamic algorithm for transplant exchange selection may have superior…

Optimization and Control · Mathematics 2023-09-26 Margarida Carvalho , Alison Caulfield , Yi Lin , Adrian Vetta

Sparsity-inducing penalties are useful tools for variable selection and they are also effective for regression settings where the data are functions. We consider the problem of selecting not only variables but also decision boundaries in…

Methodology · Statistics 2020-06-01 Hidetoshi Matsui

Estimating causal effects from observational data is challenging due to selection bias, which leads to imbalanced covariate distributions across treatment groups. Propensity score-based weighting methods are widely used to address this…

Machine Learning · Computer Science 2025-08-08 Ahmad Saeed Khan , Erik Schaffernicht , Johannes Andreas Stork

Federated learning of causal estimands offers a powerful strategy to improve estimation efficiency by leveraging data from multiple study sites while preserving privacy. Existing literature has primarily focused on the average treatment…

Methodology · Statistics 2025-11-24 Siqi Cao , Shu Yang

Federated learning (FL) has received high interest from researchers and practitioners to train machine learning (ML) models for healthcare. Ensuring the trustworthiness of these models is essential. Especially bias, defined as a disparity…

Machine Learning · Computer Science 2023-05-04 Konstantin D. Pandl , Florian Leiser , Scott Thiebes , Ali Sunyaev

For many complex diseases, prognosis is of essential importance. It has been shown that, beyond the main effects of genetic (G) and environmental (E) risk factors, the gene-environment (G$\times$E) interactions also play a critical role. In…

Applications · Statistics 2015-05-15 Hao Chai , Qingzhao Zhang , Yu Jiang , Guohua Wang , Sanguo Zhang , Shuangge Ma

Clustering analysis is one of the most widely used statistical tools in many emerging areas such as microarray data analysis. For microarray and other high-dimensional data, the presence of many noise variables may mask underlying…

Machine Learning · Statistics 2008-03-26 Benhuai Xie , Wei Pan , Xiaotong Shen

In observational studies of survival time featuring a binary time-dependent treatment, the hazard ratio (an instantaneous measure) is often used to represent the treatment effect. However, investigators are often more interested in the…

Methodology · Statistics 2020-05-21 Yun Li , Douglas E. Schaubel , Kevin He

For a data-generating process for random variables that can be described with a linear structural equation model, we consider a situation in which (i) a set of covariates satisfying the back-door criterion cannot be observed or (ii) such a…

Methodology · Statistics 2025-03-06 Hisayoshi Nanmo , Manabu Kuroki

In traditional logistic regression models, the link function is often assumed to be linear and continuous in predictors. Here, we consider a threshold model that all continuous features are discretized into ordinal levels, which further…

Methodology · Statistics 2022-02-18 Yinan Lin , Wen Zhou , Zhi Geng , Gexin Xiao , Jianxin Yin

This paper focuses on variable selection for a partially linear single-index varying-coefficient model. A regularized variable selection procedure by combining basis function approximations with SCAD penalty is proposed. It can…

Statistics Theory · Mathematics 2024-12-19 Lijuan Han , Liugen Xue , Junshan Xie

When predicting a target variable $Y$ from features $X$, the prediction $\hat{Y}$ can be performative: an agent might act on this prediction, affecting the value of $Y$ that we eventually observe. Performative predictions are deliberately…

Machine Learning · Computer Science 2024-04-09 Philip Boeken , Onno Zoeter , Joris M. Mooij

Deep learning models for survival analysis have gained significant attention in the literature, but they suffer from severe performance deficits when the dataset contains many irrelevant features. We give empirical evidence for this problem…

Machine Learning · Computer Science 2019-03-08 Carl Rietschel , Jinsung Yoon , Mihaela van der Schaar

Time-to-event models are commonly used to study associations between risk factors and disease outcomes in the setting of electronic health records (EHR). In recent years, focus has intensified on social determinants of health, highlighting…

Applications · Statistics 2025-11-26 Yueming Shen , Christian Pean , David Dunson , Samuel Berchuck

Developing predictive modelling solutions for risk estimation is extremely challenging in health-care informatics. Risk estimation involves integration of heterogeneous clinical sources having different representation from different…

Machine Learning · Computer Science 2016-09-30 Priyanka H U , Vivek R

A load sharing system has several components and the failure of one component can affect the lifetime of the surviving components. Since component failure does not equate to system failure for different system designs, the analysis of the…

Applications · Statistics 2023-07-20 Tim Pesch , Erhard Cramer , Edward Cripps , Adriano Polpo

Time-to-event modelling, known as survival analysis, differs from standard regression as it addresses censoring in patients who do not experience the event of interest. Despite competitive performances in tackling this problem, machine…

Machine Learning · Computer Science 2023-05-12 Vincent Jeanselme , Chang Ho Yoon , Brian Tom , Jessica Barrett

In survival analysis, cure models have gained much importance due to rapid advancements in medical sciences. More recently, a subset of cure models, called destructive cure models, have been studied extensively under competing risks…

Methodology · Statistics 2021-09-20 Narayanaswamy Balakrishnan , Sandip Barui
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