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Phylogeographic methods aim to infer migration trends and the history of sampled lineages from genetic data. Applications of phylogeography are broad, and in the context of pathogens include the reconstruction of transmission histories and…

Populations and Evolution · Quantitative Biology 2015-03-30 Nicola De Maio , Chieh-Hsi Wu , Kathleen M O'Reilly , Daniel Wilson

In this article, we present a recently released R package for Bayesian calibration. Many industrial fields are facing unfeasible or costly field experiments. These experiments are replaced with numerical/computer experiments which are…

Computation · Statistics 2018-08-30 Mathieu Carmassi , Pierre Barbillon , Matthieu Chiodetti , Merlin Keller , Eric Parent

A novel sequential inferential method for Bayesian dynamic generalised linear models is presented, addressing both univariate and multivariate $k$-parametric exponential families. It efficiently handles diverse responses, including…

Methodology · Statistics 2025-01-15 Mariane Branco Alves , Helio S. Migon , Silvaneo V. Santos , Raíra Marotta

Probabilistic graphical models, such as Markov random fields (MRFs), are useful for describing high-dimensional distributions in terms of local dependence structures. The probabilistic inference is a fundamental problem related to graphical…

Data Structures and Algorithms · Computer Science 2020-11-30 Weiming Feng , Kun He , Xiaoming Sun , Yitong Yin

Advancements in medical informatics tools and high-throughput biological experimentation make large-scale biomedical data routinely accessible to researchers. Competing risks data are typical in biomedical studies where individuals are at…

Computation · Statistics 2021-11-30 Eric S Kawaguchi , Jenny I Shen , Gang Li , Marc A Suchard

The INLA package provides a tool for computationally efficient Bayesian modeling and inference for various widely used models, more formally the class of latent Gaussian models. It is a non-sampling based framework which provides…

Methodology · Statistics 2019-07-26 Janet van Niekerk , Haakon Bakka , Haavard Rue , Olaf Schenk

The P\'olya tree (PT) process is a general-purpose Bayesian nonparametric model that has found wide application in a range of inference problems. It has a simple analytic form and the posterior computation boils down to beta-binomial…

Methodology · Statistics 2021-12-09 Naoki Awaya , Li Ma

Phylogenetics has seen an steady increase in substitution model complexity, which requires increasing amounts of computational power to compute likelihoods. This model complexity motivates strategies to approximate the likelihood functions…

Populations and Evolution · Quantitative Biology 2017-06-05 Brian C. Claywell , Vu C. Dinh , Connor O. McCoy , Frederick A. Matsen

A body of recent work in modeling neural activity focuses on recovering low-dimensional latent features that capture the statistical structure of large-scale neural populations. Most such approaches have focused on linear generative models,…

Neurons and Cognition · Quantitative Biology 2016-10-26 Yuanjun Gao , Evan Archer , Liam Paninski , John P. Cunningham

This article introduces epidemia, an R package for Bayesian, regression-oriented modeling of infectious diseases. The implemented models define a likelihood for all observed data while also explicitly modeling transmission dynamics: an…

The longevity R package provides provide maximum likelihood estimation routine for modelling of survival data that are subject to non-informative censoring and truncation mechanisms. It includes a selection of 12 parametric models of…

Applications · Statistics 2023-11-17 Léo R. Belzile

We propose an algorithm for the efficient and robust sampling of the posterior probability distribution in Bayesian inference problems. The algorithm combines the local search capabilities of the Manifold Metropolis Adjusted Langevin…

Phylogenetic stochastic mapping is a method for reconstructing the history of trait changes on a phylogenetic tree relating species/organisms carrying the trait. State-of-the-art methods assume that the trait evolves according to a…

Computation · Statistics 2014-03-21 Jan Irvahn , Vladimir N. Minin

Kingman's coalescent is one of the most popular models in population genetics. It describes the genealogy of a population whose genetic composition evolves in time according to the Wright-Fisher model, or suitable approximations of it…

Methodology · Statistics 2018-04-20 Stefano Favaro , Shui Feng , Paul A. Jenkins

Forward marginal effects have recently been introduced as a versatile and effective model-agnostic interpretation method particularly suited for non-linear and non-parametric prediction models. They provide comprehensible model explanations…

Machine Learning · Computer Science 2024-09-13 Holger Löwe , Christian A. Scholbeck , Christian Heumann , Bernd Bischl , Giuseppe Casalicchio

The FBMS R package facilitates Bayesian model selection and model averaging in complex regression settings by employing a variety of Monte Carlo model exploration methods. At its core, the package implements an efficient Mode Jumping Markov…

Methodology · Statistics 2025-09-03 Florian Frommlet , Jon Lachmann , Geir Storvik , Aliaksandr Hubin

Statistical analysis of agricultural experiments is based on structured experimental designs such as randomized block, factorial, split-plot, and multi-environment trials. While the theoretical bases of these approaches are sound, their…

Methodology · Statistics 2026-03-11 Aqib Gul

Modelling in biology must adapt to increasingly complex and massive data. The efficiency of the inference algorithms used to estimate model parameters is therefore questioned. Many of these are based on stochastic optimization processes…

Stochastic mapping is a simulation-based method for probabilistically mapping substitution histories onto phylogenies according to continuous-time Markov models of evolution. This technique can be used to infer properties of the…

Computation · Statistics 2017-02-10 Amrit Dhar , Vladimir N. Minin

We define the Sampled Moran Genealogy Process, a continuous-time Markov process on the space of genealogies with the demography of the classical Moran process, sampled through time. To do so, we begin by defining the Moran Genealogy Process…

Populations and Evolution · Quantitative Biology 2020-10-21 Aaron A. King , Qianying Lin , Edward L. Ionides