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The ability to extract relevant information is critical to learning. An ingenious approach as such is the information bottleneck, an optimisation problem whose solution corresponds to a faithful and memory-efficient representation of…

Quantum Physics · Physics 2023-03-08 Masahito Hayashi , Yuxiang Yang

Real-world decision-making systems are often subject to uncertainties that have to be resolved through observational data. Therefore, we are frequently confronted with combinatorial optimization problems of which the objective function is…

Machine Learning · Computer Science 2022-03-29 Guangmo Tong

Heterogeneous computing is one of the most important computational solutions to meet rapidly increasing demands on system performance. It typically allows the main flow of applications to be executed on a CPU while the most computationally…

Software Engineering · Computer Science 2020-12-11 Hugo Andrade , Ola Benderius , Christian Berger , Ivica Crnkovic , Jan Bosch

As the demand grows for scalable and privacy-aware AI systems, Federated Learning (FL) has emerged as a promising solution, allowing decentralized model training without moving raw data. At the same time, the combination of high-performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-26 Sangam Ghimire , Paribartan Timalsina , Nirjal Bhurtel , Bishal Neupane , Bigyan Byanju Shrestha , Subarna Bhattarai , Prajwal Gaire , Jessica Thapa , Sudan Jha

Artificial Intelligence for scientific applications increasingly requires training large models on data that cannot be centralized due to privacy constraints, data sovereignty, or the sheer volume of data generated. Federated learning (FL)…

Machine Learning · Computer Science 2026-03-23 Yijiang Li , Zilinghan Li , Kyle Chard , Ian Foster , Todd Munson , Ravi Madduri , Kibaek Kim

The histogram is an analysis tool in widespread use within many sciences, with high energy physics as a prime example. However, there exists an inherent bias in the choice of binning for the histogram, with different choices potentially…

Data Analysis, Statistics and Probability · Physics 2014-05-21 Abram Krislock , Nathan Krislock

The AIPC concept is gaining popularity, and more and more hybrid CPUs will be running AI models on client devices. However, the current AI inference framework overlooks the imbalanced hardware capability of hybrid CPUs, leading to low…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-02 Luo Yu , Liu Yucheng , Shen Haihao

Bilevel learning refers to machine learning problems that can be formulated as bilevel optimization models, where decisions are organized in a hierarchical structure. This paradigm has recently gained considerable attention in machine…

Optimization and Control · Mathematics 2026-05-05 Riccardo Grazzi , Massimiliano Pontil , Saverio Salzo , Alain Zemkoho

Programming for today's quantum computers is making significant strides toward modern workflows compatible with high performance computing (HPC), but fundamental challenges still remain in the integration of these vastly different…

IMPORTANCE: Modern ultrasound systems are universal diagnostic tools capable of imaging the entire body. However, current AI solutions remain fragmented into single-task tools. This critical gap between hardware versatility and software…

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

An applied problem facing all areas of data science is harmonizing data sources. Joining data from multiple origins with unmapped and only partially overlapping features is a prerequisite to developing and testing robust, generalizable…

Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

Deep learning is one of the most successful and far-reaching strategies used in machine learning today. However, the scale and utility of neural networks is still greatly limited by the current hardware used to train them. These concerns…

Machine Learning · Computer Science 2022-01-12 Davis Arthur , Prasanna Date

There is an ever-increasing need for computational power to train complex artificial intelligence (AI) & machine learning (ML) models to tackle large scientific problems. High performance computing (HPC) resources are required to…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-22 David Brayford , Sofia Vallercorsa

We give a simple, fast algorithm for hyperparameter optimization inspired by techniques from the analysis of Boolean functions. We focus on the high-dimensional regime where the canonical example is training a neural network with a large…

Machine Learning · Computer Science 2018-01-23 Elad Hazan , Adam Klivans , Yang Yuan

Today's computing systems require moving data back-and-forth between computing resources (e.g., CPUs, GPUs, accelerators) and off-chip main memory so that computation can take place on the data. Unfortunately, this data movement is a major…

Hardware Architecture · Computer Science 2022-05-31 Geraldo F. Oliveira , Amirali Boroumand , Saugata Ghose , Juan Gómez-Luna , Onur Mutlu

As the bioinformatics field grows, it must keep pace not only with new data but with new algorithms. Here we contribute a thorough analysis of 13 state-of-the-art, commonly used machine learning algorithms on a set of 165 publicly available…

Quantitative Methods · Quantitative Biology 2018-01-09 Randal S. Olson , William La Cava , Zairah Mustahsan , Akshay Varik , Jason H. Moore

One major criticism of deep learning centers around the biological implausibility of the credit assignment schema used for learning -- backpropagation of errors. This implausibility translates into practical limitations, spanning scientific…

Neural and Evolutionary Computing · Computer Science 2024-03-29 Alexander Ororbia , Ankur Mali , Adam Kohan , Beren Millidge , Tommaso Salvatori

We study the problem of computing a full Conjunctive Query in parallel using $p$ heterogeneous machines. Our computational model is similar to the MPC model, but each machine has its own cost function mapping from the number of bits it…

Databases · Computer Science 2025-03-12 Simon Frisk , Paraschos Koutris
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