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Diabetes prevalence is on the rise in the UK, and for public health strategy, estimation of relative disease risk and subsequent mapping is important. We consider an application to London data on diabetes prevalence and mortality. In order…

Applications · Statistics 2020-12-08 Marco Gramatica , Peter Congdon , Silvia Liverani

Bayesian inference for survival regression modeling offers numerous advantages, especially for decision-making and external data borrowing, but demands the specification of the baseline hazard function, which may be a challenging task. We…

In heterogeneous cohorts and those where censoring by non-primary risks is informative many conventional survival analysis methods are not applicable; the proportional hazards assumption is usually violated at population level and the…

Commonly used methods to analyze incomplete longitudinal clinical trial data include complete case analysis (CC) and last observation carried forward (LOCF). However, such methods rest on strong assumptions, including missing completely at…

Statistics Theory · Mathematics 2007-06-13 Ivy Jansen , Caroline Beunckens , Geert Molenberghs , Geert Verbeke , Craig Mallinckrodt

Early, reliable detection of disease outbreaks is a critical problem today. This paper reports an investigation of the use of causal Bayesian networks to model spatio-temporal patterns of a non-contagious disease (respiratory anthrax…

Applications · Statistics 2012-07-19 Gregory F. Cooper , Denver Dash , John Levander , Weng-Keen Wong , William Hogan , Michael Wagner

We propose a new statistical approach to obtain differential gene expression of non-detects in quantitative real-time PCR (qPCR) experiments through Bayesian hierarchical modeling. We propose to treat non-detects as non-random missing data,…

Applications · Statistics 2019-10-31 Valeriia Sherina , Matthew N. McCall , Tanzy M. T. Love

In this work, we propose a new Bayesian spatial homogeneity pursuit method for survival data under the proportional hazards model to detect spatially clustered patterns in baseline hazard and regression coefficients. Specially, regression…

Applications · Statistics 2021-02-24 Lijiang Geng , Guanyu Hu

We study the problem of missing not at random (MNAR) datasets with binary outcomes. We propose an exponential tilt based approach that bypasses any knowledge on 'nonresponse instruments' or 'shadow variables' that are usually required for…

Methodology · Statistics 2025-02-11 Subha Maity

Public health policy makers are faced with making crucial decisions rapidly during infectious disease outbreaks such as that caused by SARS-CoV-2. Ideally, rapidly deployed representative health surveys could provide needed data for such…

Applications · Statistics 2023-06-16 Yan Li , Laura Yee , Sally Hunsberger , Matthew J. Memoli , Kaitlyn Sadtler , Barry I. Graubard

The prior distribution on parameters of a sampling distribution is the usual starting point for Bayesian uncertainty quantification. In this paper, we present a different perspective which focuses on missing observations as the source of…

Methodology · Statistics 2021-11-23 Edwin Fong , Chris Holmes , Stephen G. Walker

Bayesian data analysis (BDA) is today used by a multitude of research disciplines. These disciplines use BDA as a way to embrace uncertainty by using multilevel models and making use of all available information at hand. In this chapter, we…

Software Engineering · Computer Science 2020-01-03 Richard Torkar , Robert Feldt , Carlo A. Furia

We derive a family of loss functions to train models in the presence of sampling bias. Examples are when the prevalence of a pathology differs from its sampling rate in the training dataset, or when a machine learning practioner rebalances…

Despite the recent development of methods dealing with partially observed epidemic dynamics (unobserved model coordinates, discrete and noisy outbreak data), limitations remain in practice, mainly related to the quantity of augmented data…

Applications · Statistics 2021-07-26 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Missing data are inevitable in clinical trials, and trials that produce categorical ordinal responses are not exempted from this. Typically, missing values in the data occur due to different missing mechanisms, such as missing completely at…

Methodology · Statistics 2025-05-09 Arnab Kumar Maity , Huaming Tan , Vivek Pradhan , Soutir Bandyopadhyay

Many datasets describing contacts in a population suffer from incompleteness due to population sampling and underreporting of contacts. Data-driven simulations of spreading processes using such incomplete data lead to an underestimation of…

Physics and Society · Physics 2017-09-07 Julie Fournet , Alain Barrat

Studies have shown that exposure to air pollution, even at low levels, significantly increases mortality. As regulatory actions are becoming prohibitively expensive, robust evidence to guide the development of targeted interventions to…

Applications · Statistics 2018-02-20 Kwonsang Lee , Dylan S. Small , Francesca Dominici

We propose a comprehensive Bayesian joint modeling framework for zero-inflated longitudinal count data and time-to-event outcomes, explicitly incorporating a cure fraction to account for subjects who never experience the event. The…

Methodology · Statistics 2025-08-27 Taban Baghfalaki , Mojtaba Ganjali

We consider nonparametric inference for event time distributions based on current status data. We show that in this scenario conventional mixture priors, including the popular Dirichlet process mixture prior, lead to biologically…

Methodology · Statistics 2020-09-23 Giorgio Paulon , Peter Müller , Victor G. Sal Y Rosas

Many recently developed Bayesian methods have focused on sparse signal detection. However, much less work has been done addressing the natural follow-up question: how to make valid inferences for the magnitude of those signals after…

Methodology · Statistics 2021-03-02 Spencer Woody , Oscar Hernan Madrid Padilla , James G. Scott

We consider a binary unsupervised classification problem where each observation is associated with an unobserved label that we want to retrieve. More precisely, we assume that there are two groups of observation: normal and abnormal. The…

Machine Learning · Statistics 2011-05-05 Stevenn Volant , Marie-Laure Martin Magniette , Stéphane Robin