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We consider the problem of efficiently managing massive data in a large-scale distributed environment. We consider data strings of size in the order of Terabytes, shared and accessed by concurrent clients. On each individual access, a…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-10-14 Bogdan Nicolae , Gabriel Antoniu , Luc Bougé

Matrix decomposition is one of the fundamental tools to discover knowledge from big data generated by modern applications. However, it is still inefficient or infeasible to process very big data using such a method in a single machine.…

Machine Learning · Computer Science 2020-02-11 Chihao Zhang , Yang Yang , Wei Zhang , Shihua Zhang

Image quality plays a big role in CNN-based image classification performance. Fine-tuning the network with distorted samples may be too costly for large networks. To solve this issue, we propose a transfer learning approach optimized to…

Computer Vision and Pattern Recognition · Computer Science 2019-06-04 Alessandro Bianchi , Moreno Raimondo Vendra , Pavlos Protopapas , Marco Brambilla

The advent of high-throughput sequencing technologies has revolutionized genome analysis by enabling the rapid and cost-effective sequencing of large genomes. Despite these advancements, the increasing complexity and volume of genomic data…

Genomics · Quantitative Biology 2025-03-06 Can Firtina

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Grzegorz Skorupko , Richard Osuala , Zuzanna Szafranowska , Kaisar Kushibar , Vien Ngoc Dang , Nay Aung , Steffen E Petersen , Karim Lekadir , Polyxeni Gkontra

Generating high-quality steganographic text is a fundamental challenge in the field of generative linguistic steganography. This challenge arises primarily from two aspects: firstly, the capabilities of existing models in text generation…

Computation and Language · Computer Science 2025-05-08 Yingquan Chen , Qianmu Li , Xiaocong Wu , Huifeng Li , Qing Chang

Varying-size models are often required to deploy ASR systems under different hardware and/or application constraints such as memory and latency. To avoid redundant training and optimization efforts for individual models of different sizes,…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-30 Jingjing Xu , Wei Zhou , Zijian Yang , Eugen Beck , Ralf Schlueter

High throughput sequencing of RNA (RNA-Seq) can provide us with millions of short fragments of RNA transcripts from a sample. How to better recover the original RNA transcripts from those fragments (RNA-Seq assembly) is still a difficult…

Genomics · Quantitative Biology 2019-02-15 Shunfu Mao , Yihan Jiang , Edwin Basil Mathew , Sreeram Kannan

Dataset pruning is the process of removing sub-optimal tuples from a dataset to improve the learning of a machine learning model. In this paper, we compared the performance of different algorithms, first on an unpruned dataset and then on…

Machine Learning · Computer Science 2019-01-31 Arun Thundyill Saseendran , Lovish Setia , Viren Chhabria , Debrup Chakraborty , Aneek Barman Roy

Sequence alignment data is often ordered by coordinate (id of the reference sequence plus position on the sequence where the fragment was mapped) when stored in BAM files, as this simplifies the extraction of variants between the mapped…

Genomics · Quantitative Biology 2014-06-24 German Tischler , Steven Leonard

MRI is an inherently slow process, which leads to long scan time for high-resolution imaging. The speed of acquisition can be increased by ignoring parts of the data (undersampling). Consequently, this leads to the degradation of image…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Soumick Chatterjee , Mario Breitkopf , Chompunuch Sarasaen , Hadya Yassin , Georg Rose , Andreas Nürnberger , Oliver Speck

Motivation: Recent advances in sequencing technologies promise ultra-long reads of $\sim$100 kilo bases (kb) in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 mega bases (Mb) in length. Existing…

Genomics · Quantitative Biology 2018-09-17 Heng Li

Deep Convolutional Neural Network (DCNN) and Transformer have achieved remarkable successes in image recognition. However, their performance in fine-grained image recognition is still difficult to meet the requirements of actual needs. This…

Computer Vision and Pattern Recognition · Computer Science 2021-06-08 Chaorong Li , Malu Zhang , Wei Huang , Fengqing Qin , Anping Zeng , Yuanyuan Huang

Long reads produced by third-generation sequencing technologies are used to construct an assembly (i.e., the subject's genome), which is further used in downstream genome analysis. Unfortunately, long reads have high sequencing error rates…

Genomics · Quantitative Biology 2020-10-29 Can Firtina , Jeremie S. Kim , Mohammed Alser , Damla Senol Cali , A. Ercument Cicek , Can Alkan , Onur Mutlu

The extraction of k-mers from sequencing reads is an important task in many bioinformatics applications, such as all DNA sequence analysis methods based on de Bruijn graphs. These methods tend to be more accurate when the used k-mers are…

Genomics · Quantitative Biology 2021-10-01 Miika Leinonen , Leena Salmela

Genome analysis has revolutionized fields such as personalized medicine and forensics. Modern sequencing machines generate vast amounts of fragmented strings of genome data called reads. The alignment of these reads into a complete DNA…

Hardware Architecture · Computer Science 2024-11-22 Rotem Ben-Hur , Orian Leitersdorf , Ronny Ronen , Lidor Goldshmidt , Idan Magram , Lior Kaplun , Leonid Yavitz , Shahar Kvatinsky

The success of deep learning in supervised fine-grained recognition for domain-specific tasks relies heavily on expert annotations. The Open-Set for fine-grained Self-Supervised Learning (SSL) problem aims to enhance performance on…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Prajwal Singh , Gautam Vashishtha , Indra Deep Mastan , Shanmuganathan Raman

Deep shotgun sequencing and analysis of genomes, transcriptomes, amplified single-cell genomes, and metagenomes has enabled investigation of a wide range of organisms and ecosystems. However, sampling variation in short-read data sets and…

Genomics · Quantitative Biology 2012-05-22 C. Titus Brown , Adina Howe , Qingpeng Zhang , Alexis B. Pyrkosz , Timothy H. Brom

The tremdendous advances in high-throughput sequencing technologies have made population-scale sequencing as performed in the 1000 Genomes project and the Genome of the Netherlands project possible. Next-generation sequencing has allowed…

Genomics · Quantitative Biology 2013-03-15 Tobias Marschall , Alexander Schönhuth

Convolutional Neural Networks (CNN) have gained great success in many artificial intelligence tasks. However, finding a good set of hyperparameters for a CNN remains a challenging task. It usually takes an expert with deep knowledge, and…

Neural and Evolutionary Computing · Computer Science 2020-06-25 Xueli Xiao , Ming Yan , Sunitha Basodi , Chunyan Ji , Yi Pan