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Previous works utilized ''smaller-norm-less-important'' criterion to prune filters with smaller norm values in a convolutional neural network. In this paper, we analyze this norm-based criterion and point out that its effectiveness depends…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Yang He , Ping Liu , Ziwei Wang , Zhilan Hu , Yi Yang

Background: In the metagenome assembly of a microbiome community, we may think abundant species would be easier to assemble due to their deeper coverage. However, this conjucture is rarely tested. We often do not know how many abundant…

Genomics · Quantitative Biology 2022-11-23 Xiaowen Feng , Heng Li

Recently there has been a lot of work on pruning filters from deep convolutional neural networks (CNNs) with the intention of reducing computations.The key idea is to rank the filters based on a certain criterion (say, l1-norm) and retain…

Machine Learning · Computer Science 2018-12-27 Deepak Mittal , Shweta Bhardwaj , Mitesh M. Khapra , Balaraman Ravindran

Modern high throughput sequencing technologies like metagenomic sequencing generate millions of sequences which have to be classified based on their taxonomic rank. Modern approaches either apply local alignment and comparison to existing…

Genomics · Quantitative Biology 2023-03-14 Wolfgang Fuhl , Susanne Zabel , Kay Nieselt

Deep learning (DL) techniques have shown unprecedented success when applied to images, waveforms, and text. Generally, when the sample size ($N$) is much bigger than the number of features ($d$), DL often outperforms other machine learning…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Thanh Hai Nguyen , Edi Prifti , Yann Chevaleyre , Nataliya Sokolovska , Jean-Daniel Zucker

We introduce a parallel algorithmic architecture for metagenomic sequence assembly, termed MetaPar, which allows for significant reductions in assembly time and consequently enables the processing of large genomic datasets on computers with…

Quantitative Methods · Quantitative Biology 2013-11-18 Minji Kim , Jonathan G. Ligo , Amin Emad , Farzad Farnoud , Olgica Milenkovic , Venugopal V. Veeravalli

Diffraction drastically limits the bit density in optical data storage. To increase the storage density, alternative strategies involving supplementary recording dimensions and robust read-out schemes must be explored. Here, we propose to…

Applied Physics · Physics 2020-01-28 Peter R. Wiecha , Aurélie Lecestre , Nicolas Mallet , Guilhem Larrieu

Genomic data I used in many fields but, it has become known that most of the platforms used in the sequencing process produce significant errors. This means that the analysis and inferences generated from these data may have some errors…

Genomics · Quantitative Biology 2024-09-05 Ferdinand Kartriku , Robert Sowah , Charles Saah

Deep Neural Networks (DNNs) are prone to overfitting and hence have high variance. Overfitted networks do not perform well for a new data instance. So instead of using a single DNN as classifier we propose an ensemble of seven independent…

Machine Learning · Computer Science 2021-05-11 Anmol Jain , Aishwary Kumar , Seba Susan

This paper describes an effective and efficient image classification framework nominated distributed deep representation learning model (DDRL). The aim is to strike the balance between the computational intensive deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2016-07-05 Le Dong , Na Lv , Qianni Zhang , Shanshan Xie , Ling He , Mengdie Mao

Despite the promising results of convolutional neural networks (CNNs), their application on devices with limited resources is still a big challenge; this is mainly due to the huge memory and computation requirements of the CNN. To counter…

Machine Learning · Computer Science 2020-03-04 Csanád Sándor , Szabolcs Pável , Lehel Csató

Recently there has been a lot of work on pruning filters from deep convolutional neural networks (CNNs) with the intention of reducing computations. The key idea is to rank the filters based on a certain criterion (say, $l_1$-norm, average…

Computer Vision and Pattern Recognition · Computer Science 2018-02-01 Deepak Mittal , Shweta Bhardwaj , Mitesh M. Khapra , Balaraman Ravindran

With the increasing demand for substantial amounts of high-quality data to train large language models (LLMs), efficiently filtering large web corpora has become a critical challenge. For this purpose, KenLM, a lightweight n-gram-based…

Computation and Language · Computer Science 2024-09-17 Yungi Kim , Hyunsoo Ha , Sukyung Lee , Jihoo Kim , Seonghoon Yang , Chanjun Park

Even though norm-based filter pruning methods are widely accepted, it is questionable whether the "smaller-norm-less-important" criterion is optimal in determining filters to prune. Especially when we can keep only a small fraction of the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-22 Mincheol Park , Woojeong Kim , Suhyun Kim

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

Background and Objective: Biomedical Named Entity Recognition (BioNER) is a foundational task in medical informatics, crucial for downstream applications like drug discovery and clinical trial matching. However, adapting general-domain…

Computation and Language · Computer Science 2025-12-30 Jian Chen , Leilei Su , Cong Sun

DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, such as cancer. Mapping and understanding DNAme profiles offers considerable promise for…

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

In image Super-Resolution (SR), relying on large datasets for training is a double-edged sword. While offering rich training material, they also demand substantial computational and storage resources. In this work, we analyze dataset…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Brian B. Moser , Federico Raue , Andreas Dengel