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The recent paper Cand\`es et al. (2018) introduced model-X knockoffs, a method for variable selection that provably and non-asymptotically controls the false discovery rate with no restrictions or assumptions on the dimensionality of the…

Methodology · Statistics 2020-06-16 Dongming Huang , Lucas Janson

We consider the variable selection problem, which seeks to identify important variables influencing a response $Y$ out of many candidate features $X_1, \ldots, X_p$. We wish to do so while offering finite-sample guarantees about the…

Methodology · Statistics 2019-02-12 Rina Foygel Barber , Emmanuel J. Candès , Richard J. Samworth

Controlling the False Discovery Rate (FDR) is critical for reproducible variable selection, especially given the prevalence of complex predictive modeling. The recent Split Knockoff method, an extension of the canonical Knockoffs framework,…

Methodology · Statistics 2025-09-05 Yang Cao , Hangyu Lin , Xinwei Sun , Yuan Yao

Model-X knockoffs is a general procedure that can leverage any feature importance measure to produce a variable selection algorithm, which discovers true effects while rigorously controlling the number or fraction of false positives.…

Methodology · Statistics 2020-12-07 Zhimei Ren , Yuting Wei , Emmanuel Candès

Recently, the scheme of model-X knockoffs was proposed as a promising solution to address controlled feature selection under high-dimensional finite-sample settings. However, the procedure of model-X knockoffs depends heavily on the…

Methodology · Statistics 2022-03-10 Xuebin Zhao , Hong Chen , Yingjie Wang , Weifu Li , Tieliang Gong , Yulong Wang , Feng Zheng

A new statistical procedure (Model-X \cite{candes2018}) has provided a way to identify important factors using any supervised learning method controlling for FDR. This line of research has shown great potential to expand the horizon of…

Methodology · Statistics 2018-10-01 Ying Liu , Cheng Zheng

Model-X knockoffs is a wrapper that transforms essentially any feature importance measure into a variable selection algorithm, which discovers true effects while rigorously controlling the expected fraction of false positives. A frequently…

Methodology · Statistics 2024-03-12 Stephen Bates , Emmanuel Candès , Lucas Janson , Wenshuo Wang

The knockoffs is a recently proposed powerful framework that effectively controls the false discovery rate (FDR) for variable selection. However, none of the existing knockoff solutions are directly suited to handle multivariate or…

Methodology · Statistics 2024-06-28 Xinghao Qiao , Mingya Long , Qizhai Li

Model-X knockoffs is a flexible wrapper method for high-dimensional regression algorithms, which provides guaranteed control of the false discovery rate (FDR). Due to the randomness inherent to the method, different runs of model-X…

Methodology · Statistics 2023-09-01 Zhimei Ren , Rina Foygel Barber

This paper introduces a machine for sampling approximate model-X knockoffs for arbitrary and unspecified data distributions using deep generative models. The main idea is to iteratively refine a knockoff sampling mechanism until a criterion…

Methodology · Statistics 2020-03-03 Yaniv Romano , Matteo Sesia , Emmanuel J. Candès

Model-free knockoffs is a recently proposed technique for identifying covariates that is likely to have an effect on a response variable. The method is an efficient method to control the false discovery rate in hypothesis tests for separate…

Methodology · Statistics 2019-03-29 Lars Holden , Kristoffer Hellton

Modern scientific studies often require the identification of a subset of relevant explanatory variables, in the attempt to understand an interesting phenomenon. Several statistical methods have been developed to automate this task, but…

Methodology · Statistics 2019-05-14 Matteo Sesia , Chiara Sabatti , Emmanuel J. Candès

We describe a series of algorithms that efficiently implement Gaussian model-X knockoffs to control the false discovery rate on large scale feature selection problems. Identifying the knockoff distribution requires solving a large scale…

Machine Learning · Computer Science 2020-06-17 Armin Askari , Quentin Rebjock , Alexandre d'Aspremont , Laurent El Ghaoui

The Model-X knockoff procedure has recently emerged as a powerful approach for feature selection with statistical guarantees. The advantage of knockoff is that if we have a good model of the features X, then we can identify salient features…

Machine Learning · Statistics 2019-05-30 Jaime Roquero Gimenez , James Zou

Although there is a huge literature on feature selection for the Cox model, none of the existing approaches can control the false discovery rate (FDR) unless the sample size tends to infinity. In addition, there is no formal power analysis…

Methodology · Statistics 2023-08-02 Daoji Li , Jinzhao Yu , Hui Zhao

Consider a case-control study in which we have a random sample, constructed in such a way that the proportion of cases in our sample is different from that in the general population---for instance, the sample is constructed to achieve a…

Methodology · Statistics 2019-01-01 Rina Foygel Barber , Emmanuel Candes

The fixed-X knockoff filter is a flexible framework for variable selection with false discovery rate (FDR) control in linear models with arbitrary design matrices (of full column rank) and it allows for finite-sample selective inference via…

Statistics Theory · Mathematics 2023-11-28 Mehrdad Pournaderi , Yu Xiang

Model-X knockoff has garnered significant attention among various feature selection methods due to its guarantees for controlling the false discovery rate (FDR). Since its introduction in parametric design, knockoff techniques have evolved…

Machine Learning · Computer Science 2024-11-11 Hongyu Shen , Yici Yan , Zhizhen Zhao

In many research fields, researchers aim to identify significant associations between a set of explanatory variables and a response while controlling the FDR. The Knockoff filter has been recently proposed in the frequentist paradigm to…

Methodology · Statistics 2026-04-22 Lorenzo Focardi-Olmi , Anna Gottard , Michele Guindani , Marina Vannucci

Model-X knockoffs allows analysts to perform feature selection using almost any machine learning algorithm while still provably controlling the expected proportion of false discoveries. To apply model-X knockoffs, one must construct…

Methodology · Statistics 2021-06-30 Asher Spector , Lucas Janson
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