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A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional methods of characterization. Environmental shotgun sequencing…

Genomics · Quantitative Biology 2007-08-24 Sourav Chatterji , Ichitaro Yamazaki , Zhaojun Bai , Jonathan Eisen

The mRNA optimization is critical for therapeutic and biotechnological applications, since sequence features directly govern protein expression levels and efficacy. However, current methods face significant challenges in simultaneously…

Quantitative Methods · Quantitative Biology 2025-06-02 Zheng Gong , Ziyi Jiang , Weihao Gao , Deng Zhuo , Lan Ma

Extracting an understanding of the underlying system from high dimensional data is a growing problem in science. Discovering informative and meaningful features is crucial for clustering, classification, and low dimensional data embedding.…

Machine Learning · Statistics 2019-12-10 Samuel Melton , Sharad Ramanathan

Recent advances in generative models have highlighted the need for robust detectors capable of distinguishing real images from AI-generated images. While existing methods perform well on known generators, their performance often declines…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kuo Shi , Jie Lu , Shanshan Ye , Guangquan Zhang , Zhen Fang

Functional or non-coding RNAs are attracting more attention as they are now potentially considered valuable resources in the development of new drugs intended to cure several human diseases. The identification of drugs targeting the…

Genomics · Quantitative Biology 2019-12-25 Muhammad Nabeel Asima , Muhammad Imran Malik , Andreas Dengela , Sheraz Ahmed

In this modern technological era, categorization and ranking of research journals is gaining popularity among researchers and scientists. It plays a significant role for publication of their research findings in a quality journal. Although,…

Digital Libraries · Computer Science 2022-10-07 Rabia Shabbir Ranjha , Arshad Ali , Shahid Yousaf

Deep convolutional neural networks require large amounts of labeled data samples. For many real-world applications, this is a major limitation which is commonly treated by augmentation methods. In this work, we address the problem of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Christoph Reinders , Frederik Schubert , Bodo Rosenhahn

This paper presents an effective method for fingerprint classification using data mining approach. Initially, it generates a numeric code sequence for each fingerprint image based on the ridge flow patterns. Then for each class, a seed is…

Computer Vision and Pattern Recognition · Computer Science 2012-11-21 Monowar H. Bhuyan , Sarat Saharia , Dhruba Kr Bhattacharyya

Content-based mammographic image retrieval systems require exact BIRADS categorical matching across five distinct classes, presenting significantly greater complexity than binary classification tasks commonly addressed in literature.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 MD Shaikh Rahman , Feiroz Humayara , Syed Maudud E Rabbi , Muhammad Mahbubur Rashid

In an effort to explore high-throughput processing of microscopic image data, a method based on deep convolutional neural network is proposed. The state-of-the-art computer vision algorithm, Faster R-CNN, was trained for the detection of…

Disordered Systems and Neural Networks · Physics 2021-03-09 Ze-Bin Wu

We propose rectified factor networks (RFNs) to efficiently construct very sparse, non-linear, high-dimensional representations of the input. RFN models identify rare and small events in the input, have a low interference between code units,…

Machine Learning · Computer Science 2018-01-31 Djork-Arné Clevert , Andreas Mayr , Thomas Unterthiner , Sepp Hochreiter

While data are the primary fuel for machine learning models, they often suffer from missing values, especially when collected in real-world scenarios. However, many off-the-shelf machine learning models, including artificial neural network…

Despite being the main tool to visualize molecules at the atomic scale, AFM with CO-functionalized metal tips is unable to chemically identify the observed molecules. Here we present a strategy to address this challenging task using deep…

Materials Science · Physics 2025-09-03 Jaime Carracedo-Cosme , Carlos Romero-Muñiz , Pablo Pou , Rubén Pérez

Functional miRNA--mRNA targeting is a large-bag prediction problem where each transcript yields a heavy-tailed pool of candidate target sites (CTSs), yet only a pair-level label is observed. Prior methods use max-pooling over individual CTS…

Machine Learning · Computer Science 2026-05-11 Jiaqi Yin , Baiming Chen , Jia Fei , Mingjun Yang

Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations…

Computational Engineering, Finance, and Science · Computer Science 2023-08-29 Yi Zhou , Meixuan Wu , Chengzhou Ouyang , Min Zhu

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Other Quantitative Biology · Quantitative Biology 2020-11-03 Xiangxie Zhang , Ben Beinke , Berlian Al Kindhi , Marco Wiering

The evolutionary classification of molecular clumps, crucial for understanding star formation, is commonly based on human-assigned categories derived from infrared (IR) emission and well-established morphological criteria. However, due to…

Astrophysics of Galaxies · Physics 2026-02-27 K. V. Plakitina , M. S. Kirsanova , A. B. Ostrovskii , A. D. Gimalieva , S. V. Salii , A. V. Meshcheryakov

We investigate methods of microstructure representation for the purpose of predicting processing condition from microstructure image data. A binary alloy (uranium-molybdenum) that is currently under development as a nuclear fuel was studied…

Fine-grained image classification remains challenging due to the large intra-class variance and small inter-class variance. Since the subtle visual differences are only in local regions of discriminative parts among subcategories, part…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Runsheng Zhang , jian zhang , Yaping Huang , Qi Zou

Recently, microRNAs (miRNAs) have emerged as central posttranscriptional regulators of gene expression. miRNAs regulate many key biological processes, including cell growth, death, development and differentiation. This discovery is…

Molecular Networks · Quantitative Biology 2007-12-24 Edwin Wang