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In low- and middle-income countries (LMICs), accurate estimates of subnational health and demographic indicators are critical for guiding policy and identifying disparities. Many indicators of interest are proportions of binary outcomes and…

Applications · Statistics 2025-06-23 Jon Wakefield , Peter A. Gao , Geir-Arne Fuglstad , Zehang Richard Li

Missing data theory deals with the statistical methods in the occurrence of missing data. Missing data occurs when some values are not stored or observed for variables of interest. However, most of the statistical theory assumes that data…

There has been an increasing interest in using cell and gene therapy (CGT) to treat/cure difficult diseases. The hallmark of CGT trials are the small sample size and extremely high efficacy. Due to the innovation and novelty of such…

Applications · Statistics 2025-10-23 Yaoyuan Vincent Tan , Gang Xu , Chenkun Wang

This study was sparked by an extensive longitudinal dataset focusing on HIV CD4 T$^+$ cell counts from Livingstone district, Zambia. Analysis of the corresponding histogram plots reveals an absence of symmetry in the marginal distributions,…

Methodology · Statistics 2025-05-28 Subhajit Chattopadhyay

A novel information-theoretic approach is proposed to assess the global practical identifiability of Bayesian statistical models. Based on the concept of conditional mutual information, an estimate of information gained for each model…

Methodology · Statistics 2024-04-22 Sahil Bhola , Karthik Duraisamy

A frequent problem in statistical science is how to properly handle missing data in matched paired observations. There is a large body of literature coping with the univariate case. Yet, the ongoing technological progress in measuring…

Methodology · Statistics 2022-06-06 Marcos Matabuena , Paulo Félix , Marc Ditzhaus , Juan Vidal , Francisco Gude

In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

Applications · Statistics 2015-05-27 Peter J. Diggle , Emanuele Giorgi

Approximately half of the global population does not have access to the internet, even though digital connectivity can reduce poverty by revolutionizing economic development opportunities. Due to a lack of data, Mobile Network Operators and…

Computers and Society · Computer Science 2021-06-10 Edward J. Oughton , Jatin Mathur

Rich meta-epidemiological data sets have been collected to explore associations between intervention effect estimates and study-level characteristics. Welton et al. proposed models for the analysis of meta-epidemiological data, but these…

Applications · Statistics 2017-11-28 Kirsty Rhodes , David Mawdsley , Rebecca Turner , Hayley Jones , Jelena Savovic , Julian Higgins

Missing covariates are not uncommon in capture-recapture studies. When covariate information is missing at random in capture-recapture data, an empirical full likelihood method has been demonstrated to outperform…

Methodology · Statistics 2025-07-15 Yang Liu , Yukun Liu , Pengfei Li , Riquan Zhang

Advancements in data collection techniques and the heterogeneity of data resources can yield high percentages of missing observations on variables, such as block-wise missing data. Under missing-data scenarios, traditional methods such as…

Methodology · Statistics 2022-05-17 Wei Lan , Xuerong Chen , Tao Zou , Chih-Ling Tsai

In the classical contamination models, such as the gross-error (Huber and Tukey contamination model or Case-wise Contamination), observations are considered as the units to be identified as outliers or not. This model is very useful when…

Statistics Theory · Mathematics 2021-03-11 Giovanni Saraceno , Claudio Agostinelli

Missing data is a common challenge in observational studies. Another challenge stems from the observational nature of the study itself. Here, propensity score analysis can be used as a technique to replicate conditions similar to those…

Other Statistics · Statistics 2025-10-08 Saghar Garayemi , Reza Ali Akbari Khoei , Sarah Friedrich

We consider studies where multiple measures on an outcome variable are collected over time, but some subjects drop out before the end of follow up. Analyses of such data often proceed under either a 'last observation carried forward' or…

Methodology · Statistics 2022-07-26 Oliver Dukes , David Richardson , Eric Tchetgen Tchetgen

In many observational studies in social science and medicine, subjects or units are connected, and one unit's treatment and attributes may affect another's treatment and outcome, violating the stable unit treatment value assumption (SUTVA)…

Methodology · Statistics 2024-06-25 Zhaonan Qu , Ruoxuan Xiong , Jizhou Liu , Guido Imbens

A central problem in Binary Hypothesis Testing (BHT) is to determine the optimal tradeoff between the Type I error (referred to as false alarm) and Type II (referred to as miss) error. In this context, the exponential rate of convergence of…

Information Theory · Computer Science 2021-11-29 Sebastian Espinosa , Jorge F. Silva , Pablo Piantanida

Privacy preservation is a fundamental requirement in many high-stakes domains such as medicine and finance, where sensitive personal data must be analyzed without compromising individual confidentiality. At the same time, these applications…

Machine Learning · Statistics 2026-02-05 Simon Roburin , Rafaël Pinot , Erwan Scornet

Collection of genotype data in case-control genetic association studies may often be incomplete for reasons related to genes themselves. This non-ignorable missingness structure, if not appropriately accounted for, can result in…

Methodology · Statistics 2024-07-12 Le Wang , Zhengbang Li , Ben Fitzpatrick , Clarice Weinberg , Jinbo Chen

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

Methodology · Statistics 2025-12-10 Mengqi Lin , Colin Fogarty

Importance sampling approximates expectations with respect to a target measure by using samples from a proposal measure. The performance of the method over large classes of test functions depends heavily on the closeness between both…

Computation · Statistics 2016-09-01 Daniel Sanz-Alonso