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Genetic oscillators are present in the cells of many organisms and control several biological processes. The common feature of such oscillators is the presence of a protein which represses the transcription of its own gene. Recently, it has…

Molecular Networks · Quantitative Biology 2017-06-07 Nahuel Almeira , Sebastian Risau Gusman

The task of Named Entity Recognition (NER) is an important component of many natural language processing systems, such as relation extraction and knowledge graph construction. In this work, we present a simple and effective approach for…

Computation and Language · Computer Science 2022-03-29 Urchade Zaratiana , Pierre Holat , Nadi Tomeh , Thierry Charnois

F\"orster resonant energy transfer (FRET) with upconverting nanoparticles (UCNPs) as donors and quantum dots (QDs) as acceptors has been regarded as a promising tool for biosensing applications. In this work, we use time-resolved…

Distribution of fluorescence resonance energy transfer (FRET) efficiency between the two ends of a Lennard-Jones polymer chain both at equilibrium and during folding and unfolding has been calculated, for the first time, by Brownian…

Statistical Mechanics · Physics 2007-05-23 Goundla Srinivas , Biman Bagchi

Modeling and simulation are transforming all fields of biology. Tools like AlphaFold have revolutionized structural biology, while molecular dynamics simulations provide invaluable insights into the behavior of macromolecules in solution or…

Subcellular Processes · Quantitative Biology 2024-12-19 Franco Nieto , Luis S. Mayorga

Here we report on the experimental details of a study on the influence of the photonic environment on the emission of a FRET system. We modified the local density of optical states (LDOS) by placing the FRET system at precisely defined…

Chemical Physics · Physics 2012-11-26 Niels Zijlstra , Allard P. Mosk , Willem L. Vos , Vinod Subramaniam , Christian Blum

The exponential growth of data from modern radio telescopes presents a significant challenge to traditional single-pulse search algorithms, which are computationally intensive and prone to high false-positive rates due to Radio Frequency…

Instrumentation and Methods for Astrophysics · Physics 2026-04-15 Bin Zhang , Yabiao Wang , Xiaoyao Xie , Shanping You , Xuhong Yu , Qiuhua Li , Hongwei Li , Shaowen Du , Chenchen Miao , Dengke Zhou , Jianhua Fang , Jiafu Wu , Pei Wang , Di Li

Transfer entropy (TE) is an information theoretic measure that reveals the directional flow of information between processes, providing valuable insights for a wide range of real-world applications. This work proposes Transfer Entropy…

Information Theory · Computer Science 2025-07-22 Omer Luxembourg , Dor Tsur , Haim Permuter

The transformers have achieved significant accomplishments in the natural language processing as its outstanding parallel processing capabilities and highly flexible attention mechanism. In addition, increasing studies based on transformers…

Computation and Language · Computer Science 2024-07-19 Wei Lan , Guohang He , Mingyang Liu , Qingfeng Chen , Junyue Cao , Wei Peng

Time-frequency analysis (TFA) techniques play an important role in the field of machine fault diagnosis attributing to their superiority in dealing with nonstationary signals. Synchroextracting transform (SET) and transient-extracting…

Signal Processing · Electrical Eng. & Systems 2024-02-09 Yunlong Ma , Gang Yu , Tianran Lin , Qingtang Jiang

Gene Regulatory Network (GRN) inference is essential for understanding complex cellular mechanisms, rendered tractable through single-cell transcriptomic data. With the emergence of single-cell Foundation Models (scFMs), enhanced…

Machine Learning · Computer Science 2026-05-12 Jiaxin Qi , Hang Li , Yan Cui , Yuhua Zheng , Jianqiang Huang

Modern computational organic chemistry is becoming increasingly data-driven. There remain a large number of important unsolved problems in this area such as product prediction given reactants, drug discovery, and metric-optimized molecule…

Biomolecules · Quantitative Biology 2026-02-10 Josh Payne , Mario Srouji , Dian Ang Yap , Vineet Kosaraju

Trajectory inference is a critical problem in single-cell transcriptomics, which aims to reconstruct the dynamic process underlying a population of cells from sequencing data. Of particular interest is the reconstruction of differentiation…

Genomics · Quantitative Biology 2026-04-06 Elodie Maignant , Tim Conrad , Christoph von Tycowicz

Despite the success of neural machine translation (NMT), simultaneous neural machine translation (SNMT), the task of translating in real time before a full sentence has been observed, remains challenging due to the syntactic structure…

Computation and Language · Computer Science 2020-10-06 Yun Chen , Liangyou Li , Xin Jiang , Xiao Chen , Qun Liu

Environmental monitoring is crucial to our understanding of climate change, biodiversity loss and pollution. The availability of large-scale spatio-temporal data from sources such as sensors and satellites allows us to develop sophisticated…

Advances in high-throughput sequencing technology have led to significant progress in measuring gene expressions at the single-cell level. The amount of publicly available single-cell RNA-seq (scRNA-seq) data is already surpassing 50M…

Machine Learning · Computer Science 2024-02-27 Jing Gong , Minsheng Hao , Xingyi Cheng , Xin Zeng , Chiming Liu , Jianzhu Ma , Xuegong Zhang , Taifeng Wang , Le Song

Temporal expressions in text play a significant role in language understanding and correctly identifying them is fundamental to various retrieval and natural language processing systems. Previous works have slowly shifted from rule-based to…

Computation and Language · Computer Science 2022-01-25 Satya Almasian , Dennis Aumiller , Michael Gertz

Ultrafast multistage electron transfer (ET) in molecular systems with multiple redox centers is fundamental to photochemical energy conversion, including processes in natural photosynthesis, molecular optoelectronics, and organic…

Chemical Physics · Physics 2025-07-29 Serguei Feskov , Anatoly Ivanov

Test-Time Adaptation (TTA) aims to enhance the generalization of deep learning models when faced with test data that exhibits distribution shifts from the training data. In this context, only a pre-trained model and unlabeled test data are…

Machine Learning · Computer Science 2025-05-19 Linjing You , Jiabao Lu , Xiayuan Huang , Xiangli Nie

The transfer matrix method (TMM) is widely used to analyze the transport properties of one-dimensional or quasi-one-dimensional systems, such as nanostructures and layered materials in spintronics. However, its application in quantifying…

Mesoscale and Nanoscale Physics · Physics 2024-11-12 Qiang Kang , Chenguang Hu