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The theory of life history evolution provides a powerful framework to understand the evolutionary dynamics of pathogens in both epidemic and endemic situations. This framework, however, relies on the assumption that pathogen populations are…

Populations and Evolution · Quantitative Biology 2017-11-28 Todd Parsons , Amaury Lambert , Troy Day , Sylvain Gandon

The interaction between natural selection and random mutation is frequently debated in recent years. Does similar dilemma also exist in the evolution of real networks such as biological networks? In this paper, we try to discuss this issue…

Statistical Mechanics · Physics 2009-01-07 Zhen Shao , Hai-jun Zhou

A new delay equation is introduced to describe the punctuated evolution of complex nonlinear systems. A detailed analytical and numerical investigation provides the classification of all possible types of solutions for the dynamics of a…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 V. I. Yukalov , E. P. Yukalova , D. Sornette

Normal anxiety is considered an adaptive response to the possible presence of danger, but is susceptible to dysregulation. Anxiety disorders are prevalent at high frequency in contemporary human societies, yet impose substantial disability…

Populations and Evolution · Quantitative Biology 2016-06-08 Frazer Meacham , Carl T. Bergstrom

Concomitant with the evolution of biological diversity must have been the evolution of mechanisms that facilitate evolution, due to the essentially infinite complexity of protein sequence space. We describe how evolvability can be an object…

Populations and Evolution · Quantitative Biology 2009-11-10 David J. Earl , Michael W. Deem

Biological evolution is realised through the same mechanisms of birth and death that underlie change in population density. The deep interdependence between ecology and evolution is well-established, and recent models focus on integrating…

Populations and Evolution · Quantitative Biology 2025-10-14 A. Bradley Duthie , Victor J. Luque

Theoretical analysis proves that human survivability is dominated by an unusual physical, rather than biological, mechanism, which yields an exact law. The law agrees with all experimental data, but, contrary to existing theories, it is the…

Biological Physics · Physics 2009-11-07 Mark Ya. Azbel'

The concept of fitness is central to evolution, but it quantifies only the expected number of offspring an individual will produce. The actual number of offspring is also subject to noise, arising from environmental or demographic…

Populations and Evolution · Quantitative Biology 2022-09-07 Guocheng Wang , Qi Su , Long Wang , Joshua B. Plotkin

Is evolution always gradual or can it make leaps? We examine a mathematical model of an evolutionary process on a fitness landscape and obtain analytic solutions for the probability of multi-mutation leaps, that is, several mutations…

Populations and Evolution · Quantitative Biology 2022-10-12 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

Dynamics of evolutionary games strongly depend on underlying networks. We study the coevolutionary prisoner's dilemma in which players change their local networks as well as strategies (i.e., cooperate or defect). This topic has been…

Physics and Society · Physics 2011-01-25 Yoshimi Yoshino , Naoki Masuda

A central biological question is how natural organisms are so evolvable (capable of quickly adapting to new environments). A key driver of evolvability is the widespread modularity of biological networks--their organization as functional,…

Populations and Evolution · Quantitative Biology 2015-03-13 Jeff Clune , Jean-Baptiste Mouret , Hod Lipson

The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in different contexts. Here we propose a generative model to capture the essential dynamics of survival analysis,…

Physics and Society · Physics 2015-06-18 Trevor Fenner , Mark Levene , George Loizou

In their recent comment, Cockell et al. argue that the habitability of an environment is fundamentally a binary property; that is to say, an environment can either support the metabolic processes of a given organism or not. The habitability…

Popular Physics · Physics 2020-04-15 René Heller

Sleep is considered to play an essential role in memory reorganization. Despite its importance, classical theoretical models did not focus on some sleep characteristics. Here, we review recent theoretical approaches investigating their…

Neurons and Cognition · Quantitative Biology 2023-10-23 Kensuke Yoshida , Taro Toyoizumi

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

In this paper we propose a Moran model that describes the population dynamics of two types: While the first type has a selective advantage during reproduction, the second type can avoid replacement during reproduction with some positive…

Populations and Evolution · Quantitative Biology 2026-03-02 Jochen Blath , Baptiste Le Duigou , András Tóbiás

Study Objectives: Fetal sleep is a vital yet underexplored aspect of prenatal neurodevelopment. Its cyclic organization reflects the maturation of central neural circuits, and disturbances in these patterns may offer some of the earliest…

Neurons and Cognition · Quantitative Biology 2026-01-19 Weitao Tang , Johann Vargas-Calixto , Nasim Katebi , Robert Galinsky , Gari D. Clifford , Faezeh Marzbanrad

Life systems are complex and hierarchical, with diverse components at different scales, yet they sustain themselves, grow, and evolve over time. How can a theory of such complex biological states be developed? Here we note that for a…

Biological Physics · Physics 2024-10-03 Kunihiko Kaneko

We study the evolution of recombination using a microscopic model developed within the frame of the theory of quantitative traits. Two components of fitness are considered: a static one that describes adaptation to environmental factors not…

Populations and Evolution · Quantitative Biology 2007-05-23 Franco Bagnoli , Carlo Guardiani

Evolutionary game theory has been successfully used to investigate the dynamics of systems, in which many entities have competitive interactions. From a physics point of view, it is interesting to study conditions under which a coordination…

Physics and Society · Physics 2015-05-14 Dirk Helbing , Anders Johansson