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We propose an L1-penalized algorithm for fitting high-dimensional generalized linear mixed models. Generalized linear mixed models (GLMMs) can be viewed as an extension of generalized linear models for clustered observations. This…

Computation · Statistics 2014-06-03 Jürg Schelldorfer , Lukas Meier , Peter Bühlmann

The $\ell_1$-penalized method, or the Lasso, has emerged as an important tool for the analysis of large data sets. Many important results have been obtained for the Lasso in linear regression which have led to a deeper understanding of…

Machine Learning · Statistics 2011-12-30 Jian Huang , Cun-Hui Zhang

Stochastic simulation aims to compute output performance for complex models that lack analytical tractability. To ensure accurate prediction, the model needs to be calibrated and validated against real data. Conventional methods approach…

Methodology · Statistics 2021-05-28 Yuanlu Bai , Tucker Balch , Haoxian Chen , Danial Dervovic , Henry Lam , Svitlana Vyetrenko

Kernel logistic regression (KLR) is a powerful classification method widely applied across diverse domains. In many real-world scenarios, indefinite kernels capture more domain-specific structural information than positive definite kernels.…

Machine Learning · Statistics 2025-10-31 Shaoxin Wang , Hanjing Yao

We introduce a novel scheme for choosing the regularization parameter in high-dimensional linear regression with Lasso. This scheme, inspired by Lepski's method for bandwidth selection in non-parametric regression, is equipped with both…

Methodology · Statistics 2016-11-09 Michaël Chichignoud , Johannes Lederer , Martin Wainwright

Parameter estimation connects mathematical models to real-world data and decision making across many scientific and industrial applications. Standard approaches such as maximum likelihood estimation and Markov chain Monte Carlo estimate…

Methodology · Statistics 2026-02-06 Matthew J Simpson , James S Bennett , Alexander Johnston , Ruth E Baker

Classical inference methods notoriously fail when applied to data-driven test hypotheses or inference targets. Instead, dedicated methodologies are required to obtain statistical guarantees for these selective inference problems. Selective…

Methodology · Statistics 2025-11-11 François Bachoc , Cathy Maugis-Rabusseau , Pierre Neuvial

We develop a general framework for estimating function-valued parameters under equality or inequality constraints in infinite-dimensional statistical models. Such constrained learning problems are common across many areas of statistics and…

Machine Learning · Statistics 2025-07-22 Razieh Nabi , Nima S. Hejazi , Mark J. van der Laan , David Benkeser

Regression by composition provides a flexible framework for constructing conditional distributions through sequential group actions. However, when multiple flows act on the same distribution, the model becomes non-identifiable, leading to…

Methodology · Statistics 2026-03-30 Safaa K. Kadhem

Calibration ensures that probabilistic forecasts meaningfully capture uncertainty by requiring that predicted probabilities align with empirical frequencies. However, many existing calibration methods are specialized for post-hoc…

Machine Learning · Computer Science 2023-11-01 Charles Marx , Sofian Zalouk , Stefano Ermon

Penalization procedures often suffer from their dependence on multiplying factors, whose optimal values are either unknown or hard to estimate from the data. We propose a completely data-driven calibration algorithm for this parameter in…

Statistics Theory · Mathematics 2010-07-02 Sylvain Arlot , Pascal Massart

Most supervised machine learning tasks are subject to irreducible prediction errors. Probabilistic predictive models address this limitation by providing probability distributions that represent a belief over plausible targets, rather than…

Machine Learning · Statistics 2022-10-25 David Widmann , Fredrik Lindsten , Dave Zachariah

Quantized observations are ubiquitous in a wide range of applications across engineering and the social sciences, and algorithms based on the $\ell_1$-norm are well recognized for their robustness to outliers compared with their…

Systems and Control · Electrical Eng. & Systems 2025-10-22 Xin Zheng , Yifei Jin , Yujing Liu , Lei Guo

We proposed a new penalized method in this paper to solve sparse Poisson Regression problems. Being different from $\ell_1$ penalized log-likelihood estimation, our new method can be viewed as penalized weighted score function method. We…

Statistics Theory · Mathematics 2017-03-14 Jinzhu Jia , Fang Xie , Lihu Xu

Personalized medicine has become an important part of medicine, for instance predicting individual drug responses based on genomic information. However, many current statistical methods are not tailored to this task, because they overlook…

Applications · Statistics 2019-10-03 Shih-Ting Huang , Yannick Düren , Kristoffer H. Hellton , Johannes Lederer

We propose a new estimator for the high-dimensional linear regression model with observation error in the design where the number of coefficients is potentially larger than the sample size. The main novelty of our procedure is that the…

Methodology · Statistics 2019-09-09 Alexandre Belloni , Abhishek Kaul , Mathieu Rosenbaum

Stability selection represents an attractive approach to identify sparse sets of features jointly associated with an outcome in high-dimensional contexts. We introduce an automated calibration procedure via maximisation of an in-house…

Regularization methods allow one to handle a variety of inferential problems where there are more covariates than cases. This allows one to consider a potentially enormous number of covariates for a problem. We exploit the power of these…

Methodology · Statistics 2012-10-03 Yoonkyung Lee , Steven N. MacEachern , Yoonsuh Jung

Sorted $\ell_1$ Penalized Estimator (SLOPE) is a relatively new convex regularization method for fitting high-dimensional regression models. SLOPE allows to reduce the model dimension by shrinking some estimates of the regression…

Statistics Theory · Mathematics 2022-06-17 Tomasz Skalski , Piotr Graczyk , Bartosz Kołodziejek , Maciej Wilczyński

High-dimensional data pose challenges in statistical learning and modeling. Sometimes the predictors can be naturally grouped where pursuing the between-group sparsity is desired. Collinearity may occur in real-world high-dimensional…

Machine Learning · Statistics 2011-11-11 Yiyuan She