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Finding the most effective way to aggregate multi-subject fMRI data is a long-standing and challenging problem. It is of increasing interest in contemporary fMRI studies of human cognition due to the scarcity of data per subject and the…

Functional magnetic resonance imaging (fMRI) data contain complex spatiotemporal dynamics, thus researchers have developed approaches that reduce the dimensionality of the signal while extracting relevant and interpretable dynamics. Models…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Eloy Geenjaar , Amrit Kashyap , Noah Lewis , Robyn Miller , Vince Calhoun

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Resting-state fMRI captures spontaneous neural activity characterized by complex spatiotemporal dynamics. Various metrics, such as local and global brain connectivity and low-frequency amplitude fluctuations, quantify distinct aspects of…

Neurons and Cognition · Quantitative Biology 2025-05-13 Simon Wein , Marco Riebel , Lisa-Marie Brunner , Caroline Nothdurfter , Rainer Rupprecht , Jens V. Schwarzbach

The scale of functional magnetic resonance image data is rapidly increasing as large multi-subject datasets are becoming widely available and high-resolution scanners are adopted. The inherent low-dimensionality of the information in this…

The increasing popularity of naturalistic paradigms in fMRI (such as movie watching) demands novel strategies for multi-subject data analysis, such as use of neural encoding models. In the present study, we propose a shared convolutional…

Neurons and Cognition · Quantitative Biology 2020-07-14 Meenakshi Khosla , Gia H. Ngo , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

This paper studies change-points in human brain functional connectivity (FC) and seeks patterns that are common across multiple subjects under identical external stimulus. FC relates to the similarity of fMRI responses across different…

Neurons and Cognition · Quantitative Biology 2020-03-05 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Information mapping is a popular application of Multivoxel Pattern Analysis (MVPA) to fMRI. Information maps are constructed using the so called searchlight method, where the spherical multivoxel neighborhood of every voxel (i.e., a…

Neurons and Cognition · Quantitative Biology 2012-10-24 Shivakumar Viswanathan , Matthew Cieslak , Scott T. Grafton

We propose a novel classification model for weak signal data, building upon a recent model for Bayesian multi-view learning, Group Factor Analysis (GFA). Instead of assuming all data to come from a single GFA model, we allow latent…

Machine Learning · Statistics 2016-06-08 Sami Remes , Tommi Mononen , Samuel Kaski

Functional magnetic resonance imaging (fMRI) is a notoriously noisy measurement of brain activity because of the large variations between individuals, signals marred by environmental differences during collection, and spatiotemporal…

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Due to the ever-growing diversity of the data source, multi-modality feature learning has attracted more and more attention. However, most of these methods are designed by jointly learning feature representation from multi-modalities that…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Danfeng Hong , Jocelyn Chanussot , Naoto Yokoya , Jian Kang , Xiao Xiang Zhu

In this study we focus on the problem of joint learning of multiple differential networks with function Magnetic Resonance Imaging (fMRI) data sets from multiple research centers. As the research centers may use different scanners and…

Methodology · Statistics 2021-06-08 Hao Chen , Ying Guo , Yong He , Dong Liu , Lei Liu , Xiao-Hua Zhou

Understanding cognitive processes in major depressive disorder (MDD) often relies on behavioral tasks, which are typically analyzed separately, overlooking potential correlations and shared latent structure. To address this limitation, we…

Methodology · Statistics 2026-05-26 Yuan Bian , Yuanjia Wang , Xingche Guo

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Determining the extent to which different cognitive modalities (understood here as the set of cognitive processes underlying the elaboration of a stimulus by the brain) rely on overlapping neural representations is a fundamental issue in…

Neurons and Cognition · Quantitative Biology 2019-10-14 Elena Kalinina , Fabian Pedregosa , Vittorio Iacovella , Emanuele Olivetti , Paolo Avesani

The amount of biomedical data continues to grow rapidly. However, the ability to analyze these data is limited due to privacy and regulatory concerns. Machine learning approaches that require data to be copied to a single location are…

Machine Learning · Computer Science 2021-02-18 Dimitris Stripelis , Jose Luis Ambite , Pradeep Lam , Paul Thompson

Recently, fluorescence-based optical techniques have emerged as a powerful tool to probe information in the mammalian brain. However, tissue heterogeneities prevent clear imaging of deep neuron bodies due to light scattering. While several…

In multi-contrast magnetic resonance imaging (MRI), compressed sensing theory can accelerate imaging by sampling fewer measurements within each contrast. The conventional optimization-based models suffer several limitations: strict…

Computer Vision and Pattern Recognition · Computer Science 2019-10-02 Liyan Sun , Zhiwen Fan , Yue Huang , Xinghao Ding , John Paisley

The shared response model provides a simple but effective framework to analyse fMRI data of subjects exposed to naturalistic stimuli. However when the number of subjects or runs is large, fitting the model requires a large amount of memory…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Hugo Richard , Lucas Martin , Ana Luısa Pinho , Jonathan Pillow , Bertrand Thirion
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