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The architecture of the human connectome supports efficient communication protocols relying either on distances between brain regions or on the intensities of connections. However, none of these protocols combines information about the two…

Neurons and Cognition · Quantitative Biology 2024-10-07 Laia Barjuan , Jordi Soriano , M. Ángeles Serrano

Determining important vertices in large graphs (e.g., Google's PageRank in the case of the graph of the World Wide Web) facilitated the construction of excellent web search engines, returning the most important hits corresponding to the…

Neurons and Cognition · Quantitative Biology 2021-07-06 Laszlo Keresztes , Evelin Szogi , Balint Varga , Vince Grolmusz

Graph theory in the last two decades penetrated sociology, molecular biology, genetics, chemistry, computer engineering, and numerous other fields of science. One of the more recent areas of its applications is the study of the connections…

Neurons and Cognition · Quantitative Biology 2020-03-19 Balázs Szalkai , Bálint Varga , Vince Grolmusz

Representation of brain network interactions is fundamental to the translation of neural structure to brain function. As such, methodologies for mapping neural interactions into structural models, i.e., inference of functional connectome…

Neurons and Cognition · Quantitative Biology 2022-03-18 Rahul Biswas , Eli Shlizerman

Brain connectomes, representing neural connectivity as graphs, are crucial for understanding brain organization but costly and time-consuming to acquire, motivating generative approaches. Recent advances in graph generative modeling offer a…

Machine Learning · Computer Science 2025-08-14 Yitong Luo , Islem Rekik

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

The formation of transient networks in response to external stimuli or as a reflection of internal cognitive processes is a hallmark of human brain function. However, its identification in fMRI data of the human brain is notoriously…

Neurons and Cognition · Quantitative Biology 2016-12-05 Gabriele Lohmann , Johannes Stelzer , Verena Zuber , Tilo Buschmann , Daniel Margulies , Andreas Bartels , Klaus Scheffler

Large, open-source consortium datasets have spurred the development of new and increasingly powerful machine learning approaches in brain connectomics. However, one key question remains: are we capturing biologically relevant and…

Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

Neurons and Cognition · Quantitative Biology 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

Neurons and Cognition · Quantitative Biology 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

Deep graph-theoretic ideas in the context with the graph of the World Wide Web led to the definition of Google's PageRank and the subsequent rise of the most-popular search engine to date. Brain graphs, or connectomes, are being widely…

Neurons and Cognition · Quantitative Biology 2016-02-17 Balazs Szalkai , Balint Varga , Vince Grolmusz

The white matter of the brain is organised into axonal bundles that support long-range neural communication. Although diffusion MRI (dMRI) enables detailed mapping of these pathways through tractography, how white matter pathways directly…

Neurons and Cognition · Quantitative Biology 2026-02-24 Yifei Sun , James M. Shine , Robert D. Sanders , Robin F. H. Cash , Sharon L. Naismith , Fernando Calamante , Jinglei Lv

In the study of the human connectome, the vertices and the edges of the network of the human brain are analyzed: the vertices of the graphs are the anatomically identified gray matter areas of the subjects; this set is exactly the same for…

Neurons and Cognition · Quantitative Biology 2018-11-26 Mate Fellner , Balint Varga , Vince Grolmusz

The individual course of white matter fiber tracts is an important key for analysis of white matter characteristics in healthy and diseased brains. Uniquely, diffusion-weighted MRI tractography in combination with region-based or…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Jakob Wasserthal , Peter Neher , Klaus H. Maier-Hein

This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

Computation · Statistics 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

Brain function and connectivity is a pressing mystery in medicine related to many diseases. Neural connectomes have been studied as graphs with graph theory methods including topological methods. Work has started on hypergraph models and…

Methodology · Statistics 2022-05-09 Michael G. Rawson

The human brain forms functional networks on all spatial scales. Modern fMRI scanners allow to resolve functional brain data in high resolutions, allowing to study large-scale networks that relate to cognitive processes. The analysis of…

Neurons and Cognition · Quantitative Biology 2019-05-14 Melanie Weber , Johannes Stelzer , Emil Saucan , Alexander Naitsat , Gabriele Lohmann , Jürgen Jost