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Graphical models are ubiquitous tools to describe the interdependence between variables measured simultaneously such as large-scale gene or protein expression data. Gaussian graphical models (GGMs) are well-established tools for…

Methodology · Statistics 2020-01-09 Nilabja Guha , Veera Baladandayuthapani , Bani K. Mallick

Identifying differences in networks has become a canonical problem in many biological applications. Here, we focus on testing whether two Gaussian graphical models are the same. Existing methods try to accomplish this goal by either…

Methodology · Statistics 2019-10-01 Sen Zhao , Stephen Ottinger , Suzanne Peck , Christine Mac Donald , Ali Shojaie

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

Anomaly detection in high-dimensional time series data is pivotal for numerous industrial applications. Recent advances in multivariate time series anomaly detection (TSAD) have increasingly leveraged graph structures to model…

Machine Learning · Computer Science 2025-09-23 Jiazhen Chen , Mingbin Feng , Tony S. Wirjanto

Multivariate time series anomaly detection has numerous real-world applications and is being extensively studied. Modeling pairwise correlations between variables is crucial. Existing methods employ learnable graph structures and graph…

Machine Learning · Computer Science 2025-01-24 Zehao Liu , Mengzhou Gao , Pengfei Jiao

In many statistical applications, the dimension is too large to handle for standard high-dimensional machine learning procedures. This is particularly true for graphical models, where the interpretation of a large graph is difficult and…

Statistics Theory · Mathematics 2024-05-20 Luc Devroye , Gábor Lugosi , Piotr Zwiernik

Continual graph learning (CGL) studies the problem of learning from an infinite stream of graph data, consolidating historical knowledge, and generalizing it to the future task. At once, only current graph data are available. Although some…

Machine Learning · Computer Science 2023-08-17 Qinghua Shen , Weijieying Ren , Wei Qin

The configuration model is a standard tool for uniformly generating random graphs with a specified degree sequence, and is often used as a null model to evaluate how much of an observed network's structure can be explained by its degree…

Social and Information Networks · Computer Science 2023-05-31 Upasana Dutta , Bailey K. Fosdick , Aaron Clauset

Knowledge graph completion (KGC) is a widely used method to tackle incompleteness in knowledge graphs (KGs) by making predictions for missing links. Description-based KGC leverages pre-trained language models to learn entity and relation…

Computation and Language · Computer Science 2024-03-05 Derong Xu , Ziheng Zhang , Zhenxi Lin , Xian Wu , Zhihong Zhu , Tong Xu , Xiangyu Zhao , Yefeng Zheng , Enhong Chen

Disease diagnosis on chest X-ray images is a challenging multi-label classification task. Previous works generally classify the diseases independently on the input image without considering any correlation among diseases. However, such…

Computer Vision and Pattern Recognition · Computer Science 2020-03-02 Daizong Liu , Shuangjie Xu , Pan Zhou , Kun He , Wei Wei , Zichuan Xu

Massive networks have shown that the determination of dense subgraphs, where vertices interact a lot, is necessary in order to visualize groups of common interest, and therefore be able to decompose a big graph into smaller structures. Many…

Social and Information Networks · Computer Science 2016-04-29 Etienne Callies , Tomás Yany-Anich

Graphical models are powerful tools to investigate complex dependency structures in high-throughput datasets. However, most existing graphical models make one of the two canonical assumptions: (i) a homogeneous graph with a common network…

Methodology · Statistics 2023-10-31 Tsung-Hung Yao , Yang Ni , Anindya Bhadra , Jian Kang , Veerabhadran Baladandayuthapani

Graph-structured data is a type of data to be obtained associated with a graph structure where vertices and edges describe some kind of data correlation. This paper proposes a regression method on graph-structured data, which is based on…

Machine Learning · Computer Science 2025-05-23 Ayano Nakai-Kasai , Tadashi Wadayama

This work focuses on the problem of multi-label learning with missing labels (MLML), which aims to label each test instance with multiple class labels given training instances that have an incomplete/partial set of these labels. The key…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Baoyuan Wu , Fan Jia , Wei Liu , Bernard Ghanem , Siwei Lyu

Graph-level contrastive learning, aiming to learn the representations for each graph by contrasting two augmented graphs, has attracted considerable attention. Previous studies usually simply assume that a graph and its augmented graph as a…

Artificial Intelligence · Computer Science 2024-04-15 Yanbei Liu , Yu Zhao , Xiao Wang , Lei Geng , Zhitao Xiao

Longitudinal gene expression profiles of patients are collected in some clinical studies to monitor disease progression and understand disease etiology. The identification of gene sets that have coordinated changes with relevant clinical…

Methodology · Statistics 2016-09-27 Jiehuan Sun , Jose D. Herazo-Maya , Xiu Huang , Naftali Kaminski , Hongyu Zhao

Integrative analysis of multi-level pharmacogenomic data for modeling dependencies across various biological domains is crucial for developing genomic-testing based treatments. Chain graphs characterize conditional dependence structures of…

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Identifying causative genes from patient phenotypes remains a significant challenge in precision medicine, with important implications for the diagnosis and treatment of genetic disorders. We propose a novel graph-based approach for…

Machine Learning · Computer Science 2025-06-17 Kamilia Zaripova , Ege Özsoy , Nassir Navab , Azade Farshad

Interacting systems are ubiquitous in nature and engineering, ranging from particle dynamics in physics to functionally connected brain regions. These interacting systems can be modeled by graphs where edges correspond to the interactions…

Machine Learning · Computer Science 2024-01-25 Zhichao Han , Olga Fink , David S. Kammer