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We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

Soft Condensed Matter · Physics 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

We examine the budding of a nanoscale particle through a lipid bilayer using molecular dynamics simulations, free energy calculations, and an elastic theory, with the aim of determining the extent to which equilibrium elasticity theory can…

Subcellular Processes · Quantitative Biology 2012-02-22 Teresa Ruiz-Herrero , Enrique Velasco , Michael F. Hagan

Membrane tubulation is a ubiquitous process that occurs both at the plasma membrane and on the membranes of intracellular organelles. These tubulation events are known to be mediated by forces applied on the membrane either due to motor…

Soft Condensed Matter · Physics 2020-12-03 Arijit Mahapatra , Can Uysalel , Padmini Rangamani

Narrow membrane tubes are commonly pulled out from the surface of phospholipid vesicles using forces applied either through laser or magnetic tweezers or through the action of processive motor proteins. Recent examples have emerged where…

Biological Physics · Physics 2019-02-27 Gaurav Kumar , N. Ramakrishnan , Anirban Sain

Biological membranes are shaped by various proteins that either generate inward or outward membrane curvature. In this article, we investigate the membrane morphologies induced by mixtures of arc-shaped particles with coarse-grained…

Subcellular Processes · Quantitative Biology 2020-04-03 Francesco Bonazzi , Carol K. Hall , Thomas R. Weikl

The assembly of banana-shaped rodlike proteins on membranes, and the associated membrane shape transformations, are investigated by analytical theory and coarse-grained simulations. The membrane-mediated interactions between two…

Soft Condensed Matter · Physics 2017-05-15 Hiroshi Noguchi , Jean-Baptiste Fournier

Membrane wrapping underlies nanoparticle uptake during endocytosis, whereas the reverse process of membrane unwrapping accompanies particle expulsion and membrane fusion events. Existing theoretical descriptions typically focus on adhesion…

Biological Physics · Physics 2026-04-16 Yasin Ranjbar , Yujun Teng , Haleh Alimohammadi , Huajian Gao , Mattia Bacca

Ordering nanoparticles into a desired super-structure is often crucial for their technological applications. We use molecular dynamics simulations to study the assembly of nanoparticles in a polymer brush randomly grafted to a planar…

Soft Condensed Matter · Physics 2017-12-11 Shengfeng Cheng , Mark J. Stevens , Gary S. Grest

With the rapid advent of biomedical and biotechnological innovations, a deep understanding of the nature of interaction between nanomaterials and cell membranes, tissues, and organs, has become increasingly important. Active penetration of…

Soft Condensed Matter · Physics 2019-09-26 Abdallah Daddi-Moussa-Ider , Benno Liebchen , Andreas M. Menzel , Hartmut Löwen

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

Due to the potential applications in biomedical engineering, it becomes more and more important to understand the process of engulfment and internalization of nanoparticles (NPs) by cell membranes. Despite the fact that the interaction…

Biological Physics · Physics 2023-12-12 Ke Xiao , Jing Li , Rui Ma , Chen-Xu Wu

We model the stabilization of clusters and lattices of cuboidal particles with long-ranged magnetic dipolar and short-ranged surface interactions. Two realistic systems were considered: one with magnetization orientated in the [001]…

Soft Condensed Matter · Physics 2020-09-09 Igor Stankovic , Luis Lizardi , Carlos Garcia

Surface nanobubbles are nanoscopic spherical-cap shaped gaseous domains on immersed substrates which are stable, even for days. After the stability of a {\it single} surface nanobubble has been theoretically explained, i.e. contact line…

Fluid Dynamics · Physics 2020-02-06 Xiaojue Zhu , Roberto Verzicco , Xuehua Zhang , Detlef Lohse

Spherical-cap-shaped interfacial nanobubbles (NBs) forming on hydrophobic surfaces in aqueous solutions have extensively been studied both from a fundamental point of view and due to their relevance for various practical applications. In…

Fluid Dynamics · Physics 2022-08-18 Yuliang Wang , Xiaolai Li , Shuai Ren , Hadush Tedros Alem , Lijun Yang , Detlef Lohse

We demonstrate scaffolding of plasmonic nanoparticles by topological defects induced by colloidal microspheres to match their surface boundary conditions with a uniform far-field alignment in a liquid crystal host. Displacing energetically…

Fully atomistic molecular dynamics simulations were carried out to investigate how a liquid-like water droplet behaves when into contact with a nanopore formed by carbon nanotube arrays. We have considered different tube arrays, varying the…

Mesoscale and Nanoscale Physics · Physics 2017-02-22 Ygor M. Jaques , Douglas S. Galvao

Bubble nucleation in liquid confined in nanochannel is studied using molecular dynamics simulations and compared against nucleation in the liquid over smooth (i.e. without confinement). Nucleation is achieved by heating part of a surface to…

Fluid Dynamics · Physics 2022-01-24 Manish Gupta , Shalabh C. Maroo

We analytically study membrane mediated interactions between inclusions embedded in a tubular membrane. We model inclusions as constraints coupled to the curvature tensor of the membrane tube. First, as special test cases, we analyze the…

Biological Physics · Physics 2016-09-28 Afshin Vahid , Timon Idema

Technical challenges in molecule sensing and chemical detection have created an increasing demand for transformative materials with high sensitivity and specificity. Biohybrid nanopores have attracted growing interest as they can ideally…

Biological Physics · Physics 2022-04-05 Francois Sicard , A. Ozgur Yazaydin

While evaporating solvent is a widely used technique to assemble nano-sized objects into desired superstructures, there has been limited work on how the assembled structures are affected by the physical aspects of the process. We present…

Soft Condensed Matter · Physics 2013-11-20 Shengfeng Cheng , Gary S. Grest