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Electronic health records (EHRs) are multimodal by nature, consisting of structured tabular features like lab tests and unstructured clinical notes. In real-life clinical practice, doctors use complementary multimodal EHR data sources to…

Computation and Language · Computer Science 2024-07-18 Thao Minh Nguyen Phan , Cong-Tinh Dao , Chenwei Wu , Jian-Zhe Wang , Shun Liu , Jun-En Ding , David Restrepo , Feng Liu , Fang-Ming Hung , Wen-Chih Peng

Due to the increasing adoption of electronic health records (EHR), large scale EHRs have become another rich data source for translational clinical research. Despite its potential, deriving generalizable knowledge from EHR data remains…

Machine Learning · Statistics 2023-06-01 Junwei Lu , Jin Yin , Tianxi Cai

Sequence labeling is a widely used method for named entity recognition and information extraction from unstructured natural language data. In clinical domain one major application of sequence labeling involves extraction of medical entities…

Computation and Language · Computer Science 2016-08-03 Abhyuday Jagannatha , Hong Yu

Machine learning on large-scale genomic or transcriptomic data is important for many novel health applications. For example, precision medicine tailors medical treatments to patients on the basis of individual biomarkers, cellular and…

Machine Learning · Computer Science 2025-05-26 Anika Hannemann , Jan Ewald , Leo Seeger , Erik Buchmann

The use of Electronic Health Records (EHRs) has increased dramatically in the past 15 years, as, it is considered an important source of managing data od patients. The EHRs are primary sources of disease diagnosis and demographic data of…

Machine Learning · Computer Science 2024-04-02 Bushra F. Alsaqer , Alaa F. Alsaqer , Amna Asif

Electronic health record (EHR) systems contain a wealth of multimodal clinical data including structured data like clinical codes and unstructured data such as clinical notes. However, many existing EHR-focused studies has traditionally…

Machine Learning · Statistics 2025-08-20 Tianxi Cai , Feiqing Huang , Ryumei Nakada , Linjun Zhang , Doudou Zhou

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…

Artificial Intelligence · Computer Science 2018-04-24 Anahita Hosseini , Ting Chen , Wenjun Wu , Yizhou Sun , Majid Sarrafzadeh

Healthcare is becoming a more and more important research topic recently. With the growing data in the healthcare domain, it offers a great opportunity for deep learning to improve the quality of medical service. However, the complexity of…

Computation and Language · Computer Science 2021-11-01 Bo Yang , Lijun Wu

Predicting phenotypes with complex genetic bases based on a small, interpretable set of variant features remains a challenging task. Conventionally, data-driven approaches are utilized for this task, yet the high dimensional nature of…

Machine Learning · Computer Science 2025-04-17 Joseph Lee , Shu Yang , Jae Young Baik , Xiaoxi Liu , Zhen Tan , Dawei Li , Zixuan Wen , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Li Shen

High-quality data accumulation is now becoming ubiquitous in the health domain. There is increasing opportunity to exploit rich data from normal subjects to improve supervised estimators in specific diseases with notorious data scarcity. We…

Machine Learning · Computer Science 2021-10-13 Marc-Andre Schulz , Bertrand Thirion , Alexandre Gramfort , Gaël Varoquaux , Danilo Bzdok

Electronic health records (EHR) are rich heterogeneous collection of patient health information, whose broad adoption provides great opportunities for systematic health data mining. However, heterogeneous EHR data types and biased…

Machine Learning · Computer Science 2018-11-02 Yue Li , Manolis Kellis

Current cancer screening guidelines cover only a few cancer types and rely on narrowly defined criteria such as age or a single risk factor like smoking history, to identify high-risk individuals. Predictive models using electronic health…

Machine Learning · Computer Science 2026-01-27 Jiheum Park , Chao Pang , Tristan Y. Lee , Jeong Yun Yang , Jacob Berkowitz , Alexander Z. Wei , Nicholas Tatonetti

Collaborative filtering (CF) has been successfully used to provide users with personalized products and services. However, dealing with the increasing sparseness of user-item matrix still remains a challenge. To tackle such issue, hybrid CF…

Information Retrieval · Computer Science 2017-06-14 Shuai Zhang , Lina Yao , Xiwei Xu

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

We investigate the performance and characteristics of currently available VB and MCMC software to explore the practicability of available approaches and provide guidance for clinical practitioners. Two case studies are used to fully explore…

Applications · Statistics 2024-08-29 Brian Buckley , Adrian O'Hagan , Marie Galligan

The widespread adoption of Electronic Health Record (EHR) systems in healthcare institutes has generated vast amounts of medical data, offering significant opportunities for improving healthcare services through deep learning techniques.…

Machine Learning · Computer Science 2024-01-23 Suhan Cui , Jiaqi Wang , Yuan Zhong , Han Liu , Ting Wang , Fenglong Ma

CMF is a technique for simultaneously learning low-rank representations based on a collection of matrices with shared entities. A typical example is the joint modeling of user-item, item-property, and user-feature matrices in a recommender…

Machine Learning · Statistics 2014-11-19 Arto Klami , Guillaume Bouchard , Abhishek Tripathi