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In Intensive Care Units (ICU), the abundance of multivariate time series presents an opportunity for machine learning (ML) to enhance patient phenotyping. In contrast to previous research focused on electronic health records (EHR), here we…

Machine Learning · Computer Science 2024-10-04 Hollan Haule , Ian Piper , Patricia Jones , Tsz-Yan Milly Lo , Javier Escudero

Generative models have been found effective for data synthesis due to their ability to capture complex underlying data distributions. The quality of generated data from these models is commonly evaluated by visual inspection for image…

Machine Learning · Computer Science 2022-10-18 Emily Muller , Xu Zheng , Jer Hayes

Phenotyping is fundamental to rare disease diagnosis, but manual curation of structured phenotypes from clinical notes is labor-intensive and difficult to scale. Existing artificial intelligence approaches typically optimize individual…

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

For most problems in science and engineering we can obtain data sets that describe the observed system from various perspectives and record the behavior of its individual components. Heterogeneous data sets can be collectively mined by data…

Machine Learning · Computer Science 2015-02-09 Marinka Žitnik , Blaž Zupan

Cohort studies are of significant importance in the field of healthcare analysis. However, existing methods typically involve manual, labor-intensive, and expert-driven pattern definitions or rely on simplistic clustering techniques that…

Machine Learning · Computer Science 2024-06-21 Qingpeng Cai , Kaiping Zheng , H. V. Jagadish , Beng Chin Ooi , James Yip

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack…

Machine Learning · Computer Science 2026-04-27 Hojjat Karami , David Atienza , Jean-Philippe Thiran , Anisoara Ionescu

Clinical notes contain an extensive record of a patient's health status, such as smoking status or the presence of heart conditions. However, this detail is not replicated within the structured data of electronic health systems.…

Computation and Language · Computer Science 2020-09-18 Andriy Mulyar , Elliot Schumacher , Masoud Rouhizadeh , Mark Dredze

Identifying a patient's key problems over time is a common task for providers at the point care, yet a complex and time-consuming activity given current electric health records. To enable a problem-oriented summarizer to identify a…

Applications · Statistics 2020-03-26 Gal Levy-Fix , Jason Zucker , Konstantin Stojanovic , Noémie Elhadad

In recent years, a number of methods have been developed for the dimension reduction and decomposition of multiple linked high-content data matrices. Typically these methods assume that just one dimension, rows or columns, is shared among…

Methodology · Statistics 2020-02-10 Michael J. O'Connell , Eric F. Lock

Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…

Computation and Language · Computer Science 2023-12-06 Ashwyn Sharma , David I. Feldman , Aneesh Jain

Sharing electronic health records (EHRs) on a large scale may lead to privacy intrusions. Recent research has shown that risks may be mitigated by simulating EHRs through generative adversarial network (GAN) frameworks. Yet the methods…

Machine Learning · Computer Science 2020-03-25 Chao Yan , Ziqi Zhang , Steve Nyemba , Bradley A. Malin

Background: Mining gene modules from genomic data is an important step to detect gene members of pathways or other relations such as protein-protein interactions. In this work, we explore the plausibility of detecting gene modules by…

Machine Learning · Computer Science 2017-05-12 YaoGong Zhang , YingJie Xu , Xin Fan , YuXiang Hong , Jiahui Liu , ZhiCheng He , YaLou Huang , MaoQiang Xie

Electronic Health Records (EHRs) provide vital contextual information to radiologists and other physicians when making a diagnosis. Unfortunately, because a given patient's record may contain hundreds of notes and reports, identifying…

Computational phenotyping is essential for biomedical research but often requires significant time and resources, especially since traditional methods typically involve extensive manual data review. While machine learning and natural…

Computation and Language · Computer Science 2025-07-08 Sarah Pungitore , Shashank Yadav , Vignesh Subbian

Digital healthcare systems have enabled the collection of mass healthcare data in electronic healthcare records (EHRs), allowing artificial intelligence solutions for various healthcare prediction tasks. However, existing studies often…

Machine Learning · Computer Science 2025-08-27 Zi Cai , Yu Liu , Zhiyao Luo , Tingting Zhu