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Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex…

Quantitative Methods · Quantitative Biology 2018-05-07 Alex White , Matthieu Vignes

Causal discovery studies the problem of mining causal relationships between variables from data, which is of primary interest in science. During the past decades, significant amount of progresses have been made toward this fundamental data…

Artificial Intelligence · Computer Science 2016-11-28 Kui Yu , Jiuyong Li , Lin Liu

Nonlinear causal discovery from observational data imposes strict identifiability assumptions on the formulation of structural equations utilized in the data generating process. The evaluation of structure learning methods under assumption…

Machine Learning · Statistics 2024-12-17 Georg Velev , Stefan Lessmann

Estimating causal effects from large experimental and observational data has become increasingly prevalent in both industry and research. The bootstrap is an intuitive and powerful technique used to construct standard errors and confidence…

Methodology · Statistics 2023-02-07 Matthew Kosko , Lin Wang , Michele Santacatterina

Causal inference with observational data critically relies on untestable and extra-statistical assumptions that have (sometimes) testable implications. Well-known sets of assumptions that are sufficient to justify the causal interpretation…

Methodology · Statistics 2024-02-20 Pablo Geraldo Bastías

Causal inference from observational data following the restricted structural causal models (SCM) framework hinges largely on the asymmetry between cause and effect from the data generating mechanisms, such as non-Gaussianity or…

Machine Learning · Computer Science 2024-05-30 Kang Du , Yu Xiang

The increasing capture and analysis of large-scale longitudinal health data offer opportunities to improve healthcare and advance medical understanding. However, a critical gap exists between (a) -- the observation of patterns and…

Human-Computer Interaction · Computer Science 2025-08-26 Arran Zeyu Wang , David Borland , David Gotz

Causality is crucial to understanding the mechanisms behind complex systems and making decisions that lead to intended outcomes. Event sequence data is widely collected from many real-world processes, such as electronic health records, web…

Artificial Intelligence · Computer Science 2020-11-20 Zhuochen Jin , Shunan Guo , Nan Chen , Daniel Weiskopf , David Gotz , Nan Cao

Recent years have witnessed the rapid growth of machine learning in a wide range of fields such as image recognition, text classification, credit scoring prediction, recommendation system, etc. In spite of their great performance in…

Machine Learning · Computer Science 2021-09-20 Guandong Xu , Tri Dung Duong , Qian Li , Shaowu Liu , Xianzhi Wang

Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from…

Machine Learning · Computer Science 2022-09-15 Hang Chen , Keqing Du , Xinyu Yang , Chenguang Li

The use of a hypothetical generative model was been suggested for causal analysis of observational data. The very assumption of a particular model is a commitment to a certain set of variables and therefore to a certain set of possible…

Artificial Intelligence · Computer Science 2023-06-09 Nimrod Megiddo

As any scientific discipline, the software engineering (SE) research community strives to contribute to the betterment of the target population of our research: software producers and consumers. We will only achieve this betterment if we…

Software Engineering · Computer Science 2025-11-20 Julian Frattini , Hans-Martin Heyn , Robert Feldt , Richard Torkar

Understanding directed temporal interactions in multivariate time series is essential for interpreting complex dynamical systems and the predictive models trained on them. We present Causal-INSIGHT, a model-agnostic, post-hoc interpretation…

Machine Learning · Computer Science 2026-03-27 Benjamin Redden , Hui Wang , Shuyan Li

Causal discovery aims to uncover cause-and-effect relationships encoded in causal graphs by leveraging observational, interventional data, or their combination. The majority of existing causal discovery methods are developed assuming…

Machine Learning · Computer Science 2024-06-25 Muhammad Qasim Elahi , Lai Wei , Murat Kocaoglu , Mahsa Ghasemi

Causal discovery seeks to uncover causal relations from data, typically represented as causal graphs, and is essential for predicting the effects of interventions. While expert knowledge is required to construct principled causal graphs,…

Artificial Intelligence · Computer Science 2026-02-19 Zihao Li , Fabrizio Russo

In addition to efficient statistical estimators of a treatment's effect, successful application of causal inference requires specifying assumptions about the mechanisms underlying observed data and testing whether they are valid, and to…

Methodology · Statistics 2020-11-10 Amit Sharma , Emre Kiciman

Relationship between two popular modeling frameworks of causal inference from observational data, namely, causal graphical model and potential outcome causal model is discussed. How some popular causal effect estimators found in…

Methodology · Statistics 2014-11-03 Priyantha Wijayatunga

Causal discovery from observational data is a challenging task that can only be solved up to a set of equivalent solutions, called an equivalence class. Such classes, which are often large in size, encode uncertainties about the orientation…

Machine Learning · Computer Science 2022-03-01 Philippe Brouillard , Perouz Taslakian , Alexandre Lacoste , Sebastien Lachapelle , Alexandre Drouin

At the heart of causal structure learning from observational data lies a deceivingly simple question: given two statistically dependent random variables, which one has a causal effect on the other? This is impossible to answer using…

Machine Learning · Computer Science 2020-10-13 Nikolaos Nikolaou , Konstantinos Sechidis

We develop a mathematical and interpretative foundation for the enterprise of decision-theoretic statistical causality (DT), which is a straightforward way of representing and addressing causal questions. DT reframes causal inference as…

Statistics Theory · Mathematics 2020-04-28 A. Philip Dawid