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We show that individual vibrational modes in single-molecule junctions with asymmetric molecule-lead coupling can be selectively excited by applying an external bias voltage. Thereby, a non-statistical distribution of vibrational energy can…

Mesoscale and Nanoscale Physics · Physics 2017-09-13 R. Volkovich , R. Härtle , M. Thoss , U. Peskin

We explore the possibility of designing matching mechanisms that can accommodate non-standard choice behavior. We pin down the necessary and sufficient conditions on participants' choice behavior for the existence of stable and incentive…

Theoretical Economics · Economics 2024-08-12 Gian Caspari , Manshu Khanna

Many types of cells can sense external ligand concentrations with cell-surface receptors at extremely high accuracy. Interestingly, ligand-bound receptors are often internalized, a process also known as receptor-mediated endocytosis. While…

Biological Physics · Physics 2015-05-18 Gerardo Aquino , Robert G. Endres

Understanding the binding dynamics of liquid molecules is of fundamental importance in physical and life sciences. However, nanoscale fast dynamics pose great challenges for experimental characterization. Conventionally, the binding…

Chemical Physics · Physics 2024-10-28 Shiyi Qin , Zhi Yang , Huimin Liu , Xiaoli Wang , Shangguo Hou , Kai Huang

Flow of particles of two different species through a narrow channel with solely two discrete spatial positions is analyzed with respect to the species' capability to cooperate or compete for transport. In contrast to mean field approaches,…

Soft Condensed Matter · Physics 2017-12-13 Wolfgang Rudolf Bauer

The properties of inorganic nanomaterials in adsorption, catalysis, and photoluminescence are commonly affected or dominated by particle size, surface ligand, and ligand coverage; however, it has been long remaining challenging to generally…

Materials Science · Physics 2023-04-18 Guolei Xiang

Recent air pollution issues have raised significant attention to develop efficient air filters, and one of the most promising candidates is that enabled by nanofibers. We explore here selective molecular capture mechanism for volatile…

Mesoscale and Nanoscale Physics · Physics 2014-02-06 Yu Wan , Jun Guan , Xudong Yang , Quanshui Zheng , Zhiping Xu

Biomolecular folding and function are often coupled. During molecular recognition events, one of the binding partners may transiently or partially unfold, allowing more rapid access to a binding site. We describe a simple model for this…

Soft Condensed Matter · Physics 2015-05-14 E. Trizac , Y. Levy , P. G. Wolynes

Nanobodies (Nb) are monomeric heavy-chain fragments derived from heavy-chain only antibodies naturally found in Camelids and Sharks. Their considerably small size (~3-4 nm; 13 kDa) and favorable biophysical properties make them attractive…

Multipolar electromagnetic phenomena in sub-wavelength resonators are at the heart of metamaterial science and technology. In this letter, we demonstrate selective and enhanced coupling to specific multipole resonances via beam engineering.…

Optics · Physics 2015-12-23 Tanya Das , Prasad P. Iyer , Jon A. Schuller

The influence of ligands on the low frequency vibration of different thicknesses cadmium selenide colloidal nanoplatelets is investigated using resonant low frequency Raman scattering. The strong vibration frequency shifts induced by ligand…

Nanowires play a pivotal role across a spectrum of disciplines such as nanoelectromechanical systems, nanoelectronics, and energy applications. As nanowires continue to diminish in dimensions, their mechanical characteristics are…

Materials Science · Physics 2023-08-29 Sina Zare Pakzad , Mohammad Nasr Esfahani , B. Erdem Alaca

The biophysical interactions between the T cell receptor (TCR) and its ligands determine the specificity of the cellular immune response. However, the immense diversity of receptors and ligands has made it challenging to discover…

Bistability is a major mechanism for cellular decision making and usually results from positive feedback in biochemical control systems. Here we show theoretically that bistability between unbound and bound states of adhesion clusters…

Subcellular Processes · Quantitative Biology 2010-02-24 T. Erdmann , U. S. Schwarz

Is there a unified model for generating molecules considering different conditions, such as binding pockets and chemical properties? Although target-aware generative models have made significant advances in drug design, they do not consider…

Artificial Intelligence · Computer Science 2023-02-15 Zhangyang Gao , Yuqi Hu , Cheng Tan , Stan Z. Li

To adapt their behaviour in changing environments, cells sense concentrations by binding external ligands to their receptors. However, incorrect ligands may bind nonspecifically to receptors, and when their concentration is large, this…

Molecular Networks · Quantitative Biology 2015-07-23 Thierry Mora

Molecular nanomagnets are compounds characterized by a high-spin magnetic core that is protected by organic ligands. They have recently gained attention as potential quantum information carriers in solid-state quantum computing platforms,…

Quantum Physics · Physics 2026-01-21 Alessandra Cammarata , Steve Campbell , Mauro Paternostro

When objects are packed in a cluster, physical interactions are unavoidable. Such interactions emerge because of the objects geometric features; some of these features promote entanglement, while others create repulsion. When entanglement…

Robotics · Computer Science 2024-07-26 Ashkan Rezanejad , Mostafa Mousa , Matthew Howard , Antonio Elia Forte

Inspired by dimeric motor proteins capable of undergoing transportation in living cells, significant efforts have been expended to the fabrication of track-walking nanomotors possessing two foot-like components that each can bind or detach…

Mesoscale and Nanoscale Physics · Physics 2015-05-13 Zhisong Wang

Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nano-technology. Attempts have been so far based onto microscale processing of metals and inorganic semiconductors as electrodes or…

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