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Transfer Learning enables Convolutional Neural Networks (CNN) to acquire knowledge from a source domain and transfer it to a target domain, where collecting large-scale annotated examples is time-consuming and expensive. Conventionally,…
T cell receptor (TCR) recognition of peptide-MHC (pMHC) complexes is a central component of adaptive immunity, with implications for vaccine design, cancer immunotherapy, and autoimmune disease. While recent advances in machine learning…
Domain adaptive semantic segmentation aims to transfer knowledge from a labeled source domain to an unlabeled target domain. However, existing methods primarily focus on directly learning qualified target features, making it challenging to…
The scarcity of labelled data is specifically an urgent challenge in the field of quantum machine learning (QML). Two transfer fusion frameworks are proposed in this paper to predict the labels of a target domain data by aligning its…
The recent success of deep neural networks relies on massive amounts of labeled data. For a target task where labeled data is unavailable, domain adaptation can transfer a learner from a different source domain. In this paper, we propose a…
Semantic segmentation relies on many dense pixel-wise annotations to achieve the best performance, but owing to the difficulty of obtaining accurate annotations for real world data, practitioners train on large-scale synthetic datasets.…
Non-coding RNA are functional molecules that are not translated into proteins. Their function comes as important regulators of biological function. Because they are not translated, they need not be as stable as other types of RNA. The TKF91…
Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…
Background: High-throughput techniques bring novel tools but also statistical challenges to genomic research. Identifying genes with differential expression between different species is an effective way to discover evolutionarily conserved…
Understanding gene regulation is a fundamental step towards understanding of how cells function and respond to environmental cues and perturbations. An important step in this direction is to infer the transcription factor-gene regulatory…
Understanding the binding specificity between T-cell receptors (TCRs) and peptide-major histocompatibility complexes (pMHCs) is central to immunotherapy and vaccine development. However, current predictive models struggle with…
This paper considers the estimation and prediction of a high-dimensional linear regression in the setting of transfer learning, using samples from the target model as well as auxiliary samples from different but possibly related regression…
We consider the Hypothesis Transfer Learning (HTL) problem where one incorporates a hypothesis trained on the source domain into the learning procedure of the target domain. Existing theoretical analysis either only studies specific…
Oracle bone script is the earliest-known Chinese writing system of the Shang dynasty and is precious to archeology and philology. However, real-world scanned oracle data are rare and few experts are available for annotation which make the…
The emerging field semantic communication is driving the research of end-to-end data transmission. By utilizing the powerful representation ability of deep learning models, learned data transmission schemes have exhibited superior…
To regulate a particular gene, a transcription factor (TF) needs to bind a specific genome location. How is this genome address specified amid the presence of ~10^6-10^9 decoy sites? Our analysis of 319 known TF binding motifs clearly…
This paper focuses on the problem of semi-supervised domain adaptation for time-series forecasting, which is underexplored in literatures, despite being often encountered in practice. Existing methods on time-series domain adaptation mainly…
Modern language models define distributions over strings, but downstream tasks often require different output formats. For instance, a model that generates byte-pair strings does not directly produce word-level predictions, and a DNA model…
We explore semantic segmentation beyond the conventional, single-dataset homogeneous training and bring forward the problem of Heterogeneous Training of Semantic Segmentation (HTSS). HTSS involves simultaneous training on multiple…
The Neural Tangent Kernel (NTK) characterizes how a model's state evolves over Gradient Descent. Computing the full NTK matrix is often infeasible, especially for recurrent architectures. Here, we introduce a matrix-free perspective, using…