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The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

The neural networks of the human visual brain derive representations of three-dimensional structure from specific two-dimensional image cues. Neural models backed by psychophysical data predict how local differences in either luminance…

Neurons and Cognition · Quantitative Biology 2019-12-16 Birgitta Dresp-Langley , Adam Reeves

Surface analysis of the cortex is ubiquitous in human neuroimaging with MRI, e.g., for cortical registration, parcellation, or thickness estimation. The convoluted cortical geometry requires isotropic scans (e.g., 1mm MPRAGEs) and good…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Karthik Gopinath , Douglas N. Greve , Sudeshna Das , Steve Arnold , Colin Magdamo , Juan Eugenio Iglesias

Ex vivo MRI of the brain provides remarkable advantages over in vivo MRI for visualizing and characterizing detailed neuroanatomy. However, automated cortical segmentation methods in ex vivo MRI are not well developed, primarily due to…

Evolution and its intelligence element present thrill and challenges in its exploration. Yet, how species have memory, retrieve them and maintain continuity are the fundamental questions. Most of the phenomenon can only be hypothesised by…

Neurons and Cognition · Quantitative Biology 2024-07-09 Anil Kumar Sharma , Asha Sharma

Reconstructing multiple molecularly defined neurons from individual brains and across multiple brain regions can reveal organizational principles of the nervous system. However, high resolution imaging of the whole brain is a technically…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 James Gornet , Kannan Umadevi Venkataraju , Arun Narasimhan , Nicholas Turner , Kisuk Lee , H. Sebastian Seung , Pavel Osten , Uygar Sümbül

We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Hejia Zhang , Xia Zhu , Theodore L. Willke

For the study of functional aspects of the brain network. This paper is a study on the hypergraph representation, based on the functional regions of the brain network. A new parameter that can measure how many multifunctioning regions each…

Neurons and Cognition · Quantitative Biology 2023-12-20 Anagha P , Selvakumar R

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

The study of the visual system of the brain has attracted the attention and interest of many neuro-scientists, that derived computational models of some types of neuron that compose it. These findings inspired researchers in image…

Computer Vision and Pattern Recognition · Computer Science 2021-03-03 Nicola Strisciuglio

Studying the cellular architecture of the human cerebral cortex is critical for understanding brain organization and function. It requires investigating complex texture patterns in histological images, yet automatic methods that scale…

Neurons and Cognition · Quantitative Biology 2026-03-06 Christian Schiffer , Zeynep Boztoprak , Jan-Oliver Kropp , Julia Thönnißen , Katia Berr , Hannah Spitzer , Katrin Amunts , Timo Dickscheid

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

The segregation of image parts into foreground and background is an important aspect of the neural computation of 3D scene perception. To achieve such segregation, the brain needs information about border ownership; that is, the…

Neurons and Cognition · Quantitative Biology 2018-05-22 Birgitta Dresp-Langley , Stephen Grossberg

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

In the human brain, white matter development is a complex and long-lasting process involving intermingling micro-and macrostructural mechanisms, such as fiber growth, pruning and myelination. Did you know that all these neurodevelopmental…

Neurons and Cognition · Quantitative Biology 2025-04-30 Jessica Dubois , Mareike Grotheer , Joseph Yuan-Mou Yang , Jacques-Donald Tournier , Christian Beaulieu , Catherine Lebel

Brain organoids recapitulate a number of brain properties, including neuronal diversity. However, do they recapitulate brain structure? Using a hydrodynamic description for cell nuclei as particles interacting initially via an effective,…

Soft Condensed Matter · Physics 2021-12-15 Ahmad Borzou , J. M. Schwarz

Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

Neurons and Cognition · Quantitative Biology 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Organoids are prototypes of human organs derived from cultured human stem cells. They provide a reliable and accurate experimental model to study the physical mechanisms underlying the early developmental stages of human organs…

Soft Condensed Matter · Physics 2020-02-12 Valentina Balbi , Michel Destrade , Alain Goriely