Related papers: Unsupervised cryo-EM data clustering through adapt…

K-means defines one of the most employed centroid-based clustering algorithms with performances tied to the data's embedding. Intricate data embeddings have been designed to push $K$-means performances at the cost of reduced theoretical…

Bayesian models offer great flexibility for clustering applications---Bayesian nonparametrics can be used for modeling infinite mixtures, and hierarchical Bayesian models can be utilized for sharing clusters across multiple data sets. For…

In this paper, we first propose a new iterative algorithm, called the K-sets+ algorithm for clustering data points in a semi-metric space, where the distance measure does not necessarily satisfy the triangular inequality. We show that the…

Cryo-electron microscopy (cryo-EM) studies using single particle reconstruction are extensively used to reveal structural information on macromolecular complexes. Aiming at the highest achievable resolution, state of the art electron…

Cryo-electron microscopy (EM) single particle reconstruction is an entirely general technique for 3D structure determination of macromolecular complexes. However, because the images are taken at low electron dose, it is extremely hard to…

Machine learning algorithms perform well on identifying patterns in many different datasets due to their versatility. However, as one increases the size of the dataset, the computation time for training and using these statistical models…

In sensor networks, it is not always practical to set up a fusion center. Therefore, there is need for fully decentralized clustering algorithms. Decentralized clustering algorithms should minimize the amount of data exchanged between…

This paper deals with the problem of clustering data returned by a radar sensor network that monitors a region where multiple moving targets are present. The network is formed by nodes with limited functionalities that transmit the…

The expectation-maximization (EM) algorithm is an iterative method for finding maximum likelihood estimates when data are incomplete or are treated as being incomplete. The EM algorithm and its variants are commonly used for parameter…

The popular K-means clustering algorithm potentially suffers from a major weakness for further analysis or interpretation. Some cluster may have disproportionately more (or fewer) points from one of the subpopulations in terms of some…

Clustering is an essential task to unsupervised learning. It tries to automatically separate instances into coherent subsets. As one of the most well-known clustering algorithms, k-means assigns sample points at the boundary to a unique…

One of the difficulties in 3D reconstruction of molecules from images in single particle Cryo-Electron Microscopy (Cryo-EM), in addition to high levels of noise and unknown image orientations, is heterogeneity in samples: in many cases, the…

Clustering is a usual unsupervised machine learning technique for grouping the data points into groups based upon similar features. We focus here on unsupervised clustering for contaminated data, i.e in the case where K-medians should be…

This report explores the application of machine learning techniques on short timeseries gene expression data. Although standard machine learning algorithms work well on longer time-series', they often fail to find meaningful insights from…

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…

Image processing is an important research area in computer vision. Image segmentation plays the vital rule in image processing research. There exist so many methods for image segmentation. Clustering is an unsupervised study. Clustering can…

Estimating the number of clusters (K) is a critical and often difficult task in cluster analysis. Many methods have been proposed to estimate K, including some top performers using resampling approach. When performing cluster analysis in…

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

The K-means algorithm is one of the most widely studied clustering algorithms in machine learning. While extensive research has focused on its ability to achieve a globally optimal solution, there still lacks a rigorous analysis of its…

The computational pipelines of single-particle cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) include an early particle-picking stage, in which a micrograph or tomogram is scanned to extract candidate particles,…