Related papers: Unsupervised cryo-EM data clustering through adapt…

Motivation: Structural heterogeneity in single-particle cryo-electron microscopy (cryo-EM) data represents a major challenge for high-resolution structure determination. Unsupervised classification may serve as the first step in the…

Cryo-electron microscopy (cryo-EM) has recently emerged as a powerful tool for obtaining three-dimensional (3D) structures of biological macromolecules in native states. A minimum cryo-EM image data set for deriving a meaningful…

Unsupervised classification called clustering is a process of organizing objects into groups whose members are similar in some way. Clustering of uncertain data objects is a challenge in spatial data bases. In this paper we use Probability…

Single-particle cryo-Electron Microscopy (EM) has become a popular technique for determining the structure of challenging biomolecules that are inaccessible to other technologies. Recent advances in automation, both in data collection and…

We consider the problem of data clustering with unidentified feature quality and when a small amount of labelled data is provided. An unsupervised sparse clustering method can be employed in order to detect the subgroup of features…

Clustering is an unsupervised learning method that constitutes a cornerstone of an intelligent data analysis process. It is used for the exploration of inter-relationships among a collection of patterns, by organizing them into homogeneous…

Single-particle cryo-electron microscopy (cryo-EM) is a leading technology to resolve the structure of molecules. Early in the process, the user detects potential particle images in the raw data. Typically, there are many false detections…

Big Data is a massive volume of both structured and unstructured data that is too large and it also difficult to process using traditional techniques. Clustering algorithms have developed as a powerful learning tool that can exactly analyze…

Clustering data is a popular feature in the field of unsupervised machine learning. Most algorithms aim to find the best method to extract consistent clusters of data, but very few of them intend to cluster data that share the same…

Feature selection is an important and challenging task in high dimensional clustering. For example, in genomics, there may only be a small number of genes that are differentially expressed, which are informative to the overall clustering…

The K-means one-step dimensionality reduction clustering method has made some progress in addressing the curse of dimensionality in clustering tasks. However, it combines the K-means clustering and dimensionality reduction processes for…

Motivated by the task of 2-D classification in single particle reconstruction by cryo-electron microscopy (cryo-EM), we consider the problem of heterogeneous multireference alignment of images. In this problem, the goal is to estimate a…

The analysis of continously larger datasets is a task of major importance in a wide variety of scientific fields. In this sense, cluster analysis algorithms are a key element of exploratory data analysis, due to their easiness in the…

K-means (MacQueen, 1967) [1] is one of the simplest unsupervised learning algorithms that solve the well-known clustering problem. The procedure follows a simple and easy way to classify a given data set to a predefined, say K number of…

Centroid-based clustering algorithms, such as hard K-means (HKM) and fuzzy K-means (FKM), have suffered from learning bias towards large clusters. Their centroids tend to be crowded in large clusters, compromising performance when the true…

K-means plays a vital role in data mining and is the simplest and most widely used algorithm under the Euclidean Minimum Sum-of-Squares Clustering (MSSC) model. However, its performance drastically drops when applied to vast amounts of…

The K-means algorithm is arguably the most popular data clustering method, commonly applied to processed datasets in some "feature spaces", as is in spectral clustering. Highly sensitive to initializations, however, K-means encounters a…

Cryo-electron microscopy (cryo-EM) enables single-particle analysis of biological macromolecules under strict low-dose imaging conditions, but the resulting micrographs often exhibit extremely low signal-to-noise ratios and weak particle…

Medical image analysis using supervised deep learning methods remains problematic because of the reliance of deep learning methods on large amounts of labelled training data. Although medical imaging data repositories continue to expand…

Clustering is an effective technique in data mining to generate groups that are the matter of interest. Among various clustering approaches, the family of k-means algorithms and min-cut algorithms gain most popularity due to their…