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The problem of Shannon entropy estimation in countable infinite alphabets is addressed from the study and use of convergence results of the entropy functional, which is known to be discontinuous with respect to the total variation distance…

Information Theory · Computer Science 2018-04-03 Jorge F. Silva

In this work it is shown that 20 canonical amino acids (AAs) within genetic code appear to be a whole system with strict AAs positions; more exactly, with AAs ordinal number in three variants; first variant 00-19, second 00-21 and third…

Other Quantitative Biology · Quantitative Biology 2015-06-26 Zvonimir M. Damjanovic , Miloje M. Rakocevic

The nucleotide composition of human genes with a special emphasis on transcription-related strand asymmetries is analyzed. Such asymmetries may be associated with different mutational rates in two principal factors. The first one is…

Quantitative Methods · Quantitative Biology 2010-11-10 Diana Duplij

Rich information on the prebiotic evolution is still stored in contemporary genomic data. The statistical mechanism at the sequence level may play a significant role in the prebiotic evolution. Based on statistical analysis of genome…

Other Quantitative Biology · Quantitative Biology 2018-07-12 Dirson Jian Li

Imposing a minimum principle in the framework of the so called crystal basis model of the genetic code, we determine the structure of the minimum set of 22 anticodons which allows the translational-transcription for animal mitochondrial…

Quantitative Methods · Quantitative Biology 2014-06-06 A. Sciarrino , P. Sorba

Across all kingdoms of biological life, protein-coding genes exhibit unequal usage of synonmous codons. Although alternative theories abound, translational selection has been accepted as an important mechanism that shapes the patterns of…

Genomics · Quantitative Biology 2008-03-04 Julius B. Lucks , David R. Nelson , Grzegorz Kudla , Joshua B. Plotkin

In this paper we have established relations of the genetic tables with magic and bimagic squares. Connections with Hamming distances, binomial coefficients are established. The idea of Gray code is applied. Shannon entropy of magic squares…

Information Theory · Computer Science 2012-06-12 Inder Jeet Taneja

Important aspects of the process of information storage and retrieval in DNA and RNA, and its evolution, are the role of the anticodons and associated $t$RNA's, and correlations between anticodons and amino acids; the degeneracy of the…

Biological Physics · Physics 2007-05-23 P. D. Jarvis , J. D. Bashford

New developments are presented in the framework of the model introduced by the authors in refs. [1,2] and in which nucleotides as well as codons are classified in crystal bases of the quantum group U_q(sl(2)+sl(2)) in the limit q -> 0. An…

Biological Physics · Physics 2007-05-23 L. Frappat , A. Sciarrino , P. Sorba

We studied a relations between the triplet frequency composition of mitochondria genomes, and the phylogeny of their bearers. First, the clusters in 63dimensional space were developed due to $K$-means. Second, the clade composition of those…

Genomics · Quantitative Biology 2014-05-21 Michael G. Sadovsky

Shannon information has, in the past, been applied to quantify the genetic diversity of many natural populations. Here, we apply the Shannon concept to consecutive generations of alleles as they evolve over time. We suppose a genetic system…

Populations and Evolution · Quantitative Biology 2015-12-17 J. S. Glasenapp , B. R. Frieden , C. D. Cruz

In this paper I will discuss the overlap between the concept of Shannon Entropy and the concept of electronic correlation. Quantum Monte Carlo numerical results for the uniform electron gas are also presented; these latter on the one hand…

Quantum Physics · Physics 2014-11-13 Luigi Delle Site

The coding space of protein sequences is shaped by evolutionary constraints set by requirements of function and stability. We show that the coding space of a given protein family--the total number of sequences in that family--can be…

Biomolecules · Quantitative Biology 2020-11-20 Jacopo Marchi , Ezequiel A. Galpern , Rocio Espada , Diego U. Ferreiro , Aleksandra M. Walczak , Thierry Mora

The frequencies of A, C, G and T in mitochondrial DNA vary among species due to unequal rates of mutation between the bases. The frequencies of bases at four-fold degenerate sites respond directly to mutation pressure. At 1st and 2nd…

Populations and Evolution · Quantitative Biology 2016-09-08 Daniel Urbina , Bin Tang , Paul G. Higgs

Convergent evolution provides powerful evidence for natural selection, yet its molecular basis is typically sought in protein-coding amino acid substitutions. Whether adaptive pressures can drive the convergent evolution of synonymous codon…

A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to power-law (\emph{ordered}) and exponentially (\emph{disordered})…

Genomics · Quantitative Biology 2013-10-30 Anna Carbone

Statements of Shannon's Noiseless Coding Theorem by various authors, including the original, are reviewed and clarified. Traditional statements of the theorem are often unclear as to when it applies. A new notation is introduced and the…

Information Theory · Computer Science 2010-11-01 L. F. Johnson

We present a statistical approach to protein structure by introducing a representation of protein folds based on simple observables defined as frequencies of oriented cycles in contact graphs. Motivated by the idea that these cycles may…

Biomolecules · Quantitative Biology 2016-09-08 A. M. Lisewski , O. Lichtarge

The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. Some argue that the specific form of the code with its twenty amino-acids might be a 'frozen accident' because of the overwhelming effects of any…

Quantitative Methods · Quantitative Biology 2010-07-26 Tsvi Tlusty

Electron and phonon correlations in systems of one-dimensional electrons coupled to phonons are studied at low temperatures by emphasizing on the effect of electron-phonon backward scattering. It is found that the $2k_F$-wave components of…

Strongly Correlated Electrons · Physics 2009-11-13 Leiming Chen