Related papers: Damage to white matter bottlenecks contributes to …
Structural and functional MRI studies of patients with post-stroke language deficits have contributed substantially to our understanding of how cognitive-behavioral impairments relate to the location of structural damage and to the…
Current theories of language recovery after stroke are limited by a reliance on small studies. Here, we aimed to test predictions of current theory and resolve inconsistencies regarding right hemispheric contributions to long-term recovery.…
Developmental dyslexia is characterized by persistent reading and spelling deficits. Partly due to technical challenges with investigating subcortical sensory structures, current research on dyslexia in humans by-and-large focuses on the…
Aphasia, a language disorder primarily caused by a stroke, is traditionally diagnosed using behavioral language tests. However, these tests are time-consuming, require manual interpretation by trained clinicians, suffer from low ecological…
Patients with temporal lobe epilepsy (TLE) exhibit both volumetric and structural connectivity abnormalities relative to healthy controls. How these abnormalities inter-relate and their mechanisms are unclear. We computed grey matter…
There is a growing interest in using diffusion MRI to study the white matter tracts and structural connectivity of the fetal brain. Recent progress in data acquisition and processing suggests that this imaging modality has a unique role in…
Developmental dyslexia is characterized by the inability to acquire typical reading and writing skills. Dyslexia has been frequently linked to cerebral cortex alterations; however recent evidence also points towards sensory thalamus…
Dyslexia, a neurodevelopmental disorder characterized by persistent reading difficulties, is often linked to reduced activity of the visual word form area (VWFA) in the ventral occipito-temporal cortex. Traditional approaches to studying…
One third of stroke survivors have language difficulties. Emerging evidence suggests that their likelihood of recovery depends mainly on the damage to language centers. Thus previous research for predicting language recovery post-stroke has…
Aphasias, selective language impairments which can arise from brain damage, reveal the functional organization of human language by providing causal links between affected brain regions and specific symptom profiles. Drawing on this…
This study aimed to identify white matter (WM) deficits underlying the loss of consciousness in disorder of consciousness (DOC) patients using Diffusion Tensor Imaging (DTI) and to demonstrate the potential value of DTI parameters in…
Dysarthria is a motor speech disorder caused by neurological damage that affects the muscles used for speech production, leading to slurred, slow, or difficult-to-understand speech. It affects millions of individuals worldwide, including…
[Objective]. After a stroke, one-third of patients suffer from aphasia, a language disorder that impairs communication ability. The standard behavioral tests used to diagnose aphasia are time-consuming and have low ecological validity.…
We propose a lesion-aware graph neural network (LEGNet) to predict language ability from resting-state fMRI (rs-fMRI) connectivity in patients with post-stroke aphasia. Our model integrates three components: an edge-based learning module…
Pre-surgical language mapping with functional magnetic resonance imaging (fMRI) is routinely conducted to assist the neurosurgeon in preventing damage to brain regions responsible for language. Functional differences exist between the…
Comparing information structures in between deep neural networks (DNNs) and the human brain has become a key method for exploring their similarities and differences. Recent research has shown better alignment of vision-language DNN models,…
Auditory verbal hallucinations (AVH) in schizophrenia (SZ) have been associated with abnormalities of the left arcuate fasciculus and transcallosal white matter projections linking homologous language areas of both hemispheres. While most…
Detailed assessment of language impairment following stroke remains a cognitively complex and clinician-intensive task, limiting timely and scalable diagnosis. Automatic Speech Recognition (ASR) foundation models offer a promising pathway…
The role of the motor cortex in perceptual and cognitive functions is highly controversial. Here, we investigated the hypothesis that the motor cortex can be instrumental for translating foreign language vocabulary. Participants were…
Neurodegeneration characterizes individuals with different dementia subtypes (e.g., individuals with Alzheimer's Disease, Primary Progressive Aphasia, and Parkinson's Disease), leading to progressive decline in cognitive, linguistic, and…