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Reliable seizure detection is critical for diagnosing and managing epilepsy, yet clinical workflows remain dependent on time-consuming manual EEG interpretation. While machine learning has shown promise, existing approaches often rely on…

Machine Learning · Computer Science 2025-08-12 Bartlomiej Chybowski , Shima Abdullateef , Hollan Haule , Alfredo Gonzalez-Sulser , Javier Escudero

Discriminating between Parkinson's Disease (PD) and Progressive Supranuclear Palsy (PSP) is difficult due to overlapping symptoms, especially early on. Saccades (rapid conjugate eye movements between fixation points) are affected by both…

Quantitative Methods · Quantitative Biology 2024-07-25 Salil B Patel , Oliver B Bredemeyer , James J FitzGerald , Chrystalina A Antoniades

Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting about 0.5--0.8\% of the world population. Several studies investigated the relationship between seizures and brainwave…

Machine Learning · Computer Science 2018-01-25 Paolo Detti , Garazi Zabalo Manrique de Lara , Renato Bruni , Marco Pranzo , Francesco Sarnari

Falls are detrimental to people with Parkinson's Disease (PD) because of the potentially severe consequences to the patients' quality of life. While many studies have attempted to predict falls/non-falls, this study aimed to determine…

Applications · Statistics 2019-10-07 Sarini Abdullah , James McGree , Nicole White , Kerrie Mengersen , Graham Kerr

Determining phenotypes of diseases can have considerable benefits for in-hospital patient care and to drug development. The structure of high dimensional data sets such as electronic health records are often represented through an embedding…

Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Recently, researchers have hypothesized that sepsis consists of a heterogeneous spectrum of distinct subtypes, motivating several studies to…

Applications · Statistics 2025-02-12 Alexander Dombowsky , David B. Dunson , Deng B. Madut , Matthew P. Rubach , Amy H. Herring

Ankle sprains and instability are major public health concerns. Up to 70% of individuals do not fully recover from a single ankle sprain and eventually develop chronic ankle instability (CAI). The diagnosis of CAI has been mainly based on…

Machine Learning · Computer Science 2019-11-20 Shaodi Qian , Sheng-Che Yen , Eric Folmar , Chun-An Chou

Sepsis is a condition caused by the body's overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure, and finally death. Common signs and symptoms include fever, increased heart rate, increased…

Machine Learning · Computer Science 2017-09-07 Eitam Sheetrit , Nir Nissim , Denis Klimov , Lior Fuchs , Yuval Elovici , Yuval Shahar

Clustering is a widely-used data mining tool, which aims to discover partitions of similar items in data. We introduce a new clustering paradigm, \emph{accordant clustering}, which enables the discovery of (predefined) group level insights.…

Machine Learning · Computer Science 2017-04-11 Amit Dhurandhar , Margareta Ackerman , Xiang Wang

The prevalence of suicide has been on the rise since the 20th century, causing severe emotional damage to individuals, families, and communities alike. Despite the severity of this suicide epidemic, there is so far no reliable and…

Signal Processing · Electrical Eng. & Systems 2022-06-16 Siyu Liu , Catherine Lu , Sharifa Alghowinem , Lea Gotoh , Cynthia Breazeal , Hae Won Park

Classification of seizure type is a key step in the clinical process for evaluating an individual who presents with seizures. It determines the course of clinical diagnosis and treatment, and its impact stretches beyond the clinical domain…

Signal Processing · Electrical Eng. & Systems 2024-03-06 David Ahmedt-Aristizabal , Tharindu Fernando , Simon Denman , Lars Petersson , Matthew J. Aburn , Clinton Fookes

Mouse-tracking data, which record computer mouse trajectories while participants perform an experimental task, provide valuable insights into subjects' underlying cognitive processes. Neuroscientists are interested in clustering the…

Pain is a common reason for accessing healthcare resources and is a growing area of research, especially in its overlap with mental health. Mental health electronic health records are a good data source to study this overlap. However, much…

Computation and Language · Computer Science 2023-04-06 Jaya Chaturvedi , Sumithra Velupillai , Robert Stewart , Angus Roberts

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

Epilepsy affects 50 million people worldwide and is one of the most common serious neurological disorders. Seizure detection and classification is a valuable tool for diagnosing and maintaining the condition. An automated classification…

Signal Processing · Electrical Eng. & Systems 2022-08-22 Scot Davidson , Niamh McCallan , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Accurate diagnosis is required before performing proper treatments for coronary heart disease. Machine learning based approaches have been proposed by many researchers to improve the accuracy of coronary heart disease diagnosis. Ensemble…

Machine Learning · Computer Science 2020-07-07 Kuntoro Adi Nugroho , Noor Akhmad Setiawan , Teguh Bharata Adji

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

Computers and Society · Computer Science 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

Heterogeneous data from multiple populations, sub-groups, or sources is often represented as a ``mixture model'' with a single latent class influencing all of the observed covariates. Heterogeneity can be resolved at multiple levels by…

Machine Learning · Computer Science 2024-12-16 Bijan Mazaheri , Chandler Squires , Caroline Uhler

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

Machine Learning · Computer Science 2024-06-12 Ashwin Ram