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Reaction time (RT) is a fundamental measure in cognitive and neurophysiological assessment, yet most existing RT systems require active user engagement and controlled environments, limiting their use in real-world settings. This paper…

Quantitative Methods · Quantitative Biology 2026-03-13 Abhigyan Sarkar , Boris Rubinsky

We study the problem of constructing Steiner Minimal Trees (SMTs) in hyperbolic space. Exact SMT computation is NP-hard, and existing hyperbolic heuristics such as HyperSteiner are deterministic and often get trapped in locally suboptimal…

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Cardiac magnetic resonance (CMR) imaging and computed tomography (CT) are two common non-invasive imaging methods for assessing patients with cardiovascular disease. CMR typically acquires multiple sparse 2D slices, with unavoidable…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Yiyang Xu , Hao Xu , Matthew Sinclair , Esther Puyol-Antón , Steven A Niederer , Amedeo Chiribiri , Steven E Williams , Michelle C Williams , Alistair A Young

Sampling-based motion-planning algorithms typically rely on nearest-neighbor (NN) queries when constructing a roadmap. Recent results suggest that in various settings NN queries may be the computational bottleneck of such algorithms.…

Robotics · Computer Science 2014-09-30 Michal Kleinbort , Oren Salzman , Dan Halperin

Randomized Controlled Trials (RCTs) are the gold standard for evaluating the effect of new medical treatments. Treatments must pass stringent regulatory conditions in order to be approved for widespread use, yet even after the regulatory…

Machine Learning · Statistics 2025-03-13 Omer Noy Klein , Alihan Hüyük , Ron Shamir , Uri Shalit , Mihaela van der Schaar

The Monte Carlo simulation (MCS) is a statistical methodology used in a large number of applications. It uses repeated random sampling to solve problems with a probability interpretation to obtain high-quality numerical results. The MCS is…

Discrete Mathematics · Computer Science 2022-01-19 Wei-Chang Yeh

Radiative transfer (RT) simulations are a powerful tool that enables the calculation of synthetic images of a wide range of astrophysical objects. These simulations are often based on the Monte Carlo (MC) method, as it provides the needed…

Instrumentation and Methods for Astrophysics · Physics 2023-11-23 Anton Krieger , Sebastian Wolf

Rapidly-exploring Random Tree Star(RRT*) is a recently proposed extension of Rapidly-exploring Random Tree (RRT) algorithm that provides a collision-free, asymptotically optimal path regardless of obstacle's geometry in a given environment.…

Robotics · Computer Science 2017-04-04 Ahmed Hussain Qureshi , Yasar Ayaz

Research often necessitates of samples, yet obtaining large enough samples is not always possible. When it is, the researcher may use one of two methods for deciding upon the required sample size: rules-of-thumb, quick yet uncertain, and…

Methodology · Statistics 2016-04-08 Jose D. Perezgonzalez

The Metropolis-Hastings algorithm allows one to sample asymptotically from any probability distribution $\pi$. There has been recently much work devoted to the development of variants of the MH update which can handle scenarios where such…

Computation · Statistics 2018-03-28 Christophe Andrieu , Arnaud Doucet , Sinan Yıldırım , Nicolas Chopin

Respiratory rate (RR) is a clinical metric used to assess overall health and physical fitness. An individual's RR can change from their baseline due to chronic illness symptoms (e.g., asthma, congestive heart failure), acute illness (e.g.,…

Sound · Computer Science 2021-07-30 Agni Kumar , Vikramjit Mitra , Carolyn Oliver , Adeeti Ullal , Matt Biddulph , Irida Mance

The restricted mean survival time (RMST) model has been garnering attention as a way to provide a clinically intuitive measure: the mean survival time. RMST models, which use methods based on pseudo time-to-event values and inverse…

Methodology · Statistics 2024-06-11 Keisuke Hanada , Masahiro Kojima

We present a selective sampling method designed to accelerate the training of deep neural networks. To this end, we introduce a novel measurement, the minimal margin score (MMS), which measures the minimal amount of displacement an input…

Machine Learning · Computer Science 2019-11-19 Berry Weinstein , Shai Fine , Yacov Hel-Or

Optimization-based samplers such as randomize-then-optimize (RTO) [2] provide an efficient and parallellizable approach to solving large-scale Bayesian inverse problems. These methods solve randomly perturbed optimization problems to draw…

Computation · Statistics 2019-10-29 Johnathan Bardsley , Tiangang Cui , Youssef Marzouk , Zheng Wang

In the theory of compressed sensing, restricted isometry analysis has become a standard tool for studying how efficiently a measurement matrix acquires information about sparse and compressible signals. Many recovery algorithms are known to…

Information Theory · Computer Science 2014-04-29 Holger Rauhut , Justin Romberg , Joel A. Tropp

In precision medicine, deriving the individualized treatment rule (ITR) is crucial for recommending the optimal treatment based on patients' baseline covariates. The covariate-specific treatment effect (CSTE) curve presents a graphical…

Computation · Statistics 2025-08-22 Yi Zhou , Yuhao Deng , Yu-Shi Tian , Peng Wu , Wenjie Hu , Haoxiang Wang , Ewout Steyerberg , Xiao-Hua Zhou

One of the major challenges in multivariate analysis is the estimation of population covariance matrix from sample covariance matrix (SCM). Most recent covariance matrix estimators use either shrinkage transformations or asymptotic results…

Methodology · Statistics 2019-12-10 Samruddhi Deshmukh , Amartansh Dubey

Randomized clinical trials are the gold standard when estimating the average treatment effect. However, they are usually not a random sample from the real-world population because of the inclusion/exclusion rules. Meanwhile, observational…

Methodology · Statistics 2024-12-11 Kuan Jiang , Wenjie Hu , Shu Yang , Xinxing Lai , Xiaohua Zhou

During the last decade, sampling-based path planning algorithms, such as Probabilistic RoadMaps (PRM) and Rapidly-exploring Random Trees (RRT), have been shown to work well in practice and possess theoretical guarantees such as…

Robotics · Computer Science 2011-05-09 Sertac Karaman , Emilio Frazzoli