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This PhD thesis is focused on the central idea that single neurons in the brain should be regarded as temporally precise and highly complex spatio-temporal pattern recognizers. This is opposed to the prevalent view of biological neurons as…

Neurons and Cognition · Quantitative Biology 2023-09-27 David Beniaguev

Traditional artificial neural networks take inspiration from biological networks, using layers of neuron-like nodes to pass information for processing. More realistic models include spiking in the neural network, capturing the electrical…

Machine Learning · Computer Science 2025-03-11 Christopher S. Yang , Sylvester J. Gates , Dulara De Zoysa , Jaehoon Choe , Wolfgang Losert , Corey B. Hart

Understanding how the dynamics of neural networks is shaped by the computations they perform is a fundamental question in neuroscience. Recently, the framework of efficient coding proposed a theory of how spiking neural networks can compute…

Neurons and Cognition · Quantitative Biology 2022-10-25 Veronika Koren , Stefano Panzeri

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Neurons and Cognition · Quantitative Biology 2021-04-15 Rosa Cao , Daniel Yamins

Spike-timing dependent plasticity in biological neural networks has been proven to be important during biological learning process. On the other hand, artificial neural networks use a different way to learn, such as Back-Propagation or…

Neural and Evolutionary Computing · Computer Science 2022-06-29 Shiyuan Li

Hierarchically modular organization is a canonical network topology that is evolutionarily conserved in the nervous systems of animals. Within the network, neurons form directional connections defined by the growth of their axonal…

Neurons and Cognition · Quantitative Biology 2024-04-26 Nobuaki Monma , Hideaki Yamamoto , Naoya Fujiwara , Hakuba Murota , Satoshi Moriya , Ayumi Hirano-Iwata , Shigeo Sato

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

The hippocampus has the capacity for reactivating recently acquired memories [1-3] and it is hypothesized that one of the functions of sleep reactivation is the facilitation of consolidation of novel memory traces [4-11]. The dynamic and…

Neurons and Cognition · Quantitative Biology 2015-06-26 Piotr Jablonski , Gina R. Poe , Michal Zochowski

We investigate the performance of sparsely-connected networks of integrate-and-fire neurons for ultra-short term information processing. We exploit the fact that the population activity of networks with balanced excitation and inhibition…

Neurons and Cognition · Quantitative Biology 2007-05-23 Julien Mayor , Wulfram Gerstner

Patterns of microcircuitry suggest that the brain has an array of repeated canonical computational units. Yet neural representations are distributed, so the relevant computations may only be related indirectly to single-neuron…

Neurons and Cognition · Quantitative Biology 2023-10-17 Rajkumar Vasudeva Raju , Zhe Li , Scott Linderman , Xaq Pitkow

Complex systems in the real world can be modeled as a network of connected components. The human brain, as a network of neurons among which the interactions cause perception, is a complex network. Synchronization is a dynamical phenomenon…

Biological Physics · Physics 2019-04-30 Arefeh Mazarei , Mohammad Amirian Matlob , Gholamhossein Riazi , Yousef Jamali

Neuromorphic computing is emerging to be a disruptive computational paradigm that attempts to emulate various facets of the underlying structure and functionalities of the brain in the algorithm and hardware design of next-generation…

Neural and Evolutionary Computing · Computer Science 2020-11-17 Mehul Rastogi , Sen Lu , Nafiul Islam , Abhronil Sengupta

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Efficient pattern separation in dentate gyrus plays an important role in storing information in the hippocampus. Current knowledge of the structure and function of the hippocampus, entorhinal cortex and dentate gyrus, in pattern separation…

Neurons and Cognition · Quantitative Biology 2018-08-02 Faramarz Faghihi , Homa Samani , Ahmed A. Moustafa

Our brain consists of biological neurons encoding information through accurate spike timing, yet both the architecture and learning rules of our brain remain largely unknown. Comparing to the recent development of backpropagation-based…

Neural and Evolutionary Computing · Computer Science 2021-11-29 Yukun Yang , Peng Li

In this paper a model of neural circuit in the brain has been proposed which is composed of cyclic sub-circuits. A big loop has been defined to be consisting of a feed forward path from the sensory neurons to the highest processing area of…

Neurons and Cognition · Quantitative Biology 2007-06-16 Kaushik Majumdar

Spiking neural networks are motivated from principles of neural systems and may possess unexplored advantages in the context of machine learning. A class of \textit{convolutional spiking neural networks} is introduced, trained to detect…

Neural and Evolutionary Computing · Computer Science 2018-08-27 Daniel J. Saunders , Hava T. Siegelmann , Robert Kozma , Miklós Ruszinkó

Biological systems use neural circuits to integrate input information and produce outputs. Synaptic convergence, where multiple neurons converge their inputs onto a single downstream neuron, is common in natural neural circuits. However,…

Mesoscale and Nanoscale Physics · Physics 2026-02-04 Wendy Otieno , Alex Gabbitas , Debi Pattnaik , Pavel Borisov , Sergey Savel'ev , Alexander G. Balanov

Identifying the physiological processes underlying the emergence and maintenance of consciousness is one of the most fundamental problems of neuroscience, with implications ranging from fundamental neuroscience to the treatment of patients…

Neurons and Cognition · Quantitative Biology 2019-07-29 Julien Modolo , Mahmoud Hassan , Fabrice Wendling , Pascal Benquet

In the mammalian brain, newly acquired memories depend on the hippocampus for maintenance and recall, but over time the neocortex takes over these functions, rendering memories hippocampus-independent. The process responsible for this…

Neurons and Cognition · Quantitative Biology 2021-07-02 Peter Helfer , Thomas R. Shultz