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Information encoding in the nervous system is supported through the precise spike-timings of neurons; however, an understanding of the underlying processes by which such representations are formed in the first place remains unclear. Here we…

Neural and Evolutionary Computing · Computer Science 2015-12-01 Brian Gardner , Ioana Sporea , André Grüning

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neurons and Cognition · Quantitative Biology 2026-05-01 Terrence J. Sejnowski

The neural networks of the brain are capable of learning statistical input regularities on the basis of synaptic learning, functional integration into increasingly larger, interconnected neural assemblies, and self organization. This self…

Robotics · Computer Science 2022-06-10 Birgitta Dresp-Langley

Determining how synaptic coupling within and between regions is modulated during sensory processing is an important topic in neuroscience. Electrophysiological recordings provide detailed information about neural spiking but have…

Neurons and Cognition · Quantitative Biology 2018-02-07 Andrea K. Barreiro , Shree Hari Gautam , Woodrow L. Shew , Cheng Ly

Networks of interconnected neurons communicating through spiking signals offer the bedrock of neural computations. Our brains spiking neural networks have the computational capacity to achieve complex pattern recognition and cognitive…

Neural and Evolutionary Computing · Computer Science 2024-12-06 Naresh Ravichandran , Anders Lansner , Pawel Herman

Neuroscience has long informed the development of artificial neural networks, but the success of modern architectures invites, in turn, the converse: can modern networks teach us lessons about brain function? Here, we examine the structure…

Neurons and Cognition · Quantitative Biology 2026-03-17 Peter Koenig , Mario Negrello

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jordan Guergiuev , Timothy P. Lillicrap , Blake A. Richards

Learning in the brain requires complementary mechanisms: potentiation and activity-dependent homeostatic scaling. We introduce synaptic scaling to a biologically-realistic spiking model of neocortex which can learn changes in oscillatory…

Neurons and Cognition · Quantitative Biology 2013-04-09 Mark Rowan , Samuel Neymotin

A sufficiently large information flux in recurrent neural networks, quantified by the mutual information between successive network states, is considered a prerequisite for rich information processing capabilities. This raises the question…

Neurons and Cognition · Quantitative Biology 2026-05-15 Claus Metzner , Ali Ghebleh , Karin Prebeck , Achim Schilling , Andreas Maier , Thomas Kinfe , Patrick Krauss

The fields of artificial intelligence and neuroscience have a long history of fertile bi-directional interactions. On the one hand, important inspiration for the development of artificial intelligence systems has come from the study of…

Neurons and Cognition · Quantitative Biology 2019-11-21 Eilif B. Muller , Philippe Beaudoin

Neural systems process information across a broad range of intrinsic timescales, both within and across cortical areas. While such diversity is a hallmark of biological networks, its computational role in nonlinear information processing…

Neurons and Cognition · Quantitative Biology 2025-06-10 Tomoki Kurikawa

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Biological neurons exhibit remarkable intelligence: they maintain internal states, communicate selectively with other neurons, and self-organize into complex graphs rather than rigid hierarchical layers. What if artificial intelligence…

Machine Learning · Computer Science 2025-12-01 Antoine Salomon

Cortical microcircuits are very complex networks, but they are composed of a relatively small number of stereotypical motifs. Hence one strategy for throwing light on the computational function of cortical microcircuits is to analyze…

Neurons and Cognition · Quantitative Biology 2017-05-23 Zeno Jonke , Robert Legenstein , Stefan Habenschuss , Wolfgang Maass

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

We propose a formal mathematical model for sparse representations and active dendrites in neocortex. Our model is inspired by recent experimental findings on active dendritic processing and NMDA spikes in pyramidal neurons. These…

Neurons and Cognition · Quantitative Biology 2016-05-16 Subutai Ahmad , Jeff Hawkins

The neuronal networks in the mammals cortex are characterized by the coexistence of hierarchy, modularity, short and long range interactions, spatial correlations, and topographical connections. Particularly interesting, the latter type of…

Disordered Systems and Neural Networks · Physics 2009-11-10 Luciano da F. Costa , Luis Diambra

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

Neurons and Cognition · Quantitative Biology 2022-04-15 Sean Knight , Navjot Gadda

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

Neurons and Cognition · Quantitative Biology 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns