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Biological transport networks adapt through dynamic interactions between material transport and structural modification during growth and development. In this work, we present a model of transport network growth driven by local material…

Biological Physics · Physics 2025-03-27 Chanoknun Sintavanuruk , Yoichiro Mori , Reza Farhadifar , Eleni Katifori

Space-saving design is a requirement that is encountered in biological systems and the development of modern technological devices alike. Many living organisms dynamically pack their polymer chains, filaments or membranes inside of…

Soft Condensed Matter · Physics 2014-07-18 Roman Vetter , Falk K. Wittel , Hans J. Herrmann

Recently acoustic signature of dislocation avalanches in HCP materials was found to be long tailed in size and energy, suggesting critical dynamics. Even more recently, the intermittent plastic response was found to be generic for micro-…

Mesoscale and Nanoscale Physics · Physics 2021-05-25 Jérôme Weiss , Peng Zhang , Oguz Umut Salman , Gang Liu , Lev Truskinovsky

We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a growing collective show the emergence of concentric-ring…

Biological Physics · Physics 2024-05-17 Scott Weady , Bryce Palmer , Adam Lamson , Taeyoon Kim , Reza Farhadifar , Michael J. Shelley

Mathematical modelling of the evolution of the size-spectrum dynamics in aquatic ecosystems was discovered to be a powerful tool to have a deeper insight into impacts of human- and environmental driven changes on the marine ecosystem. In…

Analysis of PDEs · Mathematics 2024-01-02 Laura Kanzler , Benoit Perthame , Benoit Sarels

The prevailing theory for metabolic scaling is based on area-preserved, space-filling fractal vascular networks. However, it's known both theoretically and experimentally that animals' vascular systems obey Murray's cubic branching law.…

Quantitative Methods · Quantitative Biology 2022-05-31 Jinkui Zhao

Self-organisation is the spontaneous emergence of spatio-temporal structures and patterns from the interaction of smaller individual units. Examples are found across many scales in very different systems and scientific disciplines, from…

The growth of several biological tissues is known to be controlled in part by local geometrical features, such as the curvature of the tissue interface. This control leads to changes in tissue shape that in turn can affect the tissue's…

Tissues and Organs · Quantitative Biology 2016-12-01 Almie Alias , Pascal R Buenzli

Interconnected ensembles of biological entities are perhaps some of the most complex systems that modern science has encountered so far. In particular, scientists have concentrated on understanding how the complexity of the interacting…

Pattern Formation and Solitons · Physics 2020-11-18 Bram A. Siebert , Cameron L. Hall , James P. Gleeson , Malbor Asllani

There is an abundance of literature on complex networks describing a variety of relationships among units in social, biological, and technological systems. Such networks, consisting of interconnected nodes, are often self-organized,…

Adaptation and Self-Organizing Systems · Physics 2011-08-18 Paul J. Laurienti , Karen E. Joyce , Qawi K. Telesford , Jonathan H. Burdette , Satoru Hayasaka

Spider silk is a remarkable biomaterial with exceptional stiffness, strength, and toughness stemming from a unique microstructure. While recent studies show that silk fibers exhibit plasticity, hysteresis, and recovery under cyclic loading,…

Soft Condensed Matter · Physics 2026-05-11 Renata Olivé , José Pérez-Riguero , Noy Cohen

At the heart of many contemporary theories of life is the concept of biological self-organisation: organisms have to continuously produce and maintain the conditions of their own existence in order to stay alive. The way in which these…

Quantitative Methods · Quantitative Biology 2025-03-17 Emmy Brown , Sean T. Vittadello

Dormancy is an essential strategy for microorganisms to cope with environmental stress. However, global ecosystem models typically ignore microbial dormancy, resulting in major model uncertainties. To facilitate the consideration of…

Quantitative Methods · Quantitative Biology 2014-02-20 Gangsheng Wang , Melanie A. Mayes , Lianhong Gu , Christopher W. Schadt

Metabolic allometry, a common pattern in nature, is a close-to-3/4-power scaling law between metabolic rate and body mass in organisms, across and within species. An analogous relationship between metabolic rate and water volume in river…

Optimization and Control · Mathematics 2014-03-05 Lily Briggs , Mukkai Krishnamoorthy

Shape is one of the important characteristics for the structures observed in living organisms. Whereas biologists have proposed models where the shape is controlled on a molecular level [1], physicists, following Turing [2] and d'Arcy…

Tissues and Organs · Quantitative Biology 2010-10-11 Etienne Couturier , Sylvain Courrech du Pont , Stephane Douady

This work is motivated by the mostly unsolved task of parsing biological images with multiple overlapping articulated model organisms (such as worms or larvae). We present a general approach that separates the two main challenges associated…

Computer Vision and Pattern Recognition · Computer Science 2016-12-20 Victor Yurchenko , Victor Lempitsky

Shape-programmed sheets morph from one surface into another upon activation by stimuli such as illumination, and have attracted much interest for their potential engineering applications, especially in soft robotics. Complex shape changes…

Soft Condensed Matter · Physics 2024-10-17 Daniel Duffy , Itay Griniasty , John Biggins , Cyrus Mostajeran

In this thesis, we have studied the large scale structure and system level dynamics of certain biological networks using tools from graph theory, computational biology and dynamical systems. We study the structure and dynamics of large…

Molecular Networks · Quantitative Biology 2008-12-31 Areejit Samal

It has recently been discovered that many biological systems, when represented as graphs, exhibit a scale-free topology. One such system is the set of structural relationships among protein domains. The scale-free nature of this and other…

Populations and Evolution · Quantitative Biology 2009-11-10 Eric J. Deeds , Eugene I. Shakhnovich